Precision Psychiatry Approach to Treat Depression and Anxiety Targeting the Stress Hormone System - V1b-antagonists as a Case in Point [0.03%]
精准精神病学治疗抑郁症和焦虑症方法——以针对压力激素系统的V1b受体拮抗剂为例
Florian Holsboer,Marcus Ising
Florian Holsboer
The future of depression pharmacotherapy lies in a precision medicine approach that recognizes that depression is a disease where different causalities drive symptoms. That approach calls for a departure from current diagnostic categories, ...
SARS-CoV-2-Infection in People Addicted to Illegal Drugs - Is There a Protective Effect of Opioid Maintenance Treatment? [0.03%]
非法药物成瘾者感染SARS-CoV-2的情况——阿片类维持治疗有保护作用吗？
Simon Kurzhals,Martin Schäfer,Udo Bonnet et al.
Simon Kurzhals et al.
Introduction: People addicted to illegal drugs were discussed as a risk group for SARS-CoV-2 infections, with increased susceptibility and a severe course of infection. ...
Recreational Cannabis Legalization: No Contribution to Rising Prescription Stimulants in the USA [0.03%]
娱乐性大麻合法化不会导致美国处方兴奋剂使用增加
Garrett D Alexander,Luke R Cavanah,Jessica L Goldhirsh et al.
Garrett D Alexander et al.
Introduction: There have been substantial increases in the use of Schedule II stimulants in the United States. Schedule II stimulants are the gold standard treatment for attention-deficit hyperactivity disorder (ADHD), bu...
A Trajectory of Long-Term Antipsychotic Medication Dosage in Inpatients with Severe Behavioral and Psychological Symptoms of Dementia: A Retrospective Study [0.03%]
重症行为和心理症状痴呆住院患者长期抗精神病药物剂量轨迹：一项回顾性研究
Teruo Tada,Takefumi Suzuki,Yusuke Iwata et al.
Teruo Tada et al.
Introduction: While antipsychotics are often prescribed for behavioral and psychological symptoms of dementia (BPSD), typically on an off-label basis, these medications have serious adverse effects. This study investigate...
Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 Study [0.03%]
escitalopram和aripiprazole治疗抑郁症结局的整合遗传变异、DNA甲基化和基因表达分析：CAN-BIND-1研究
Farhana Islam,Amanda Lisoway,Edward S Oh et al.
Farhana Islam et al.
Introduction: Little is known about the interplay between genetics and epigenetics on antidepressant treatment (1) response and remission, (2) side effects, and (3) serum levels. This study explored the relationship among...
Management of Refractory Functional Gastrointestinal Disorders: What Role Should Psychiatrists Have? [0.03%]
难治性功能性胃肠病的管理：精神科医生应发挥什么作用？
Mohsen Khosravi,Abdullah A Alzahrani,Thikra M Muhammed et al.
Mohsen Khosravi et al.
Currently, it has been stated that psychiatric and psychological problems are equally paramount aspects of the clinical modulation and manifestation of both the central nervous and digestive systems, which could be used to restore balance. ...
Discontinuation Rate of Lurasidone and Quetiapine Extended Release in Bipolar Depression [0.03%]
鲁拉西 tone和喹硫平缓释片治疗双相抑郁的停药率
Taro Kishi,Kenji Sakuma,Shun Hamanaka et al.
Taro Kishi et al.
Introduction: Lurasidone (LUR) was compared with quetiapine extended release (QUE-ER) regarding 1-year discontinuation in patients with bipolar depression (n=317). ...
Kirsten R Müller-Vahl,Georg Juckel
Kirsten R Müller-Vahl
Advancements in Non-Dopaminergic Treatments for Schizophrenia: A Systematic Review of Pipeline Developments [0.03%]
精神分裂症非多巴胺能治疗的进展：系统评价管道发展的趋势
Yuki Komatsu,Moe Takehara,Xenia Hart et al.
Yuki Komatsu et al.
Introduction: Conventional antipsychotic drugs that attenuate dopaminergic neural transmission are ineffective in approximately one-third of patients with schizophrenia. This necessitates the development of non-dopaminerg...
Viktória Meszár,Gabriella Magyar,Gabriella Mészárosné Pásztor et al.
Viktória Meszár et al.
Introduction: Cariprazine is an atypical dopamine receptor partial agonist antipsychotic available in the form of capsules. Although capsules are one of the most desirable routes of administration, there are certain situa...
Clinical Trial
Pharmacopsychiatry. 2024 Jul;57(4):180-185. DOI:10.1055/a-2291-7130 2024