Rapid Antidepressant and Antisuicidal Effects of Low-Dose Ketamine Infusion in Patients With Treatment-Resistant Depression With or Without Low-Grade Inflammation [0.03%]
低剂量氯胺酮快速抗抑郁和抗自杀效应：一项针对难治性抑郁症患者（伴或不伴轻度炎症）的研究
Mu-Hong Chen,Tung-Ping Su,Wei-Chen Lin et al.
Mu-Hong Chen et al.
Low-grade inflammation (LGI) contributes to resistance against traditional antidepressants. However, whether the antidepressant and antisuicidal effects of ketamine on patients with treatment-resistant depression (TRD) differ between those ...
Exposure to Psychotropic Drugs and Colorectal Cancer Risk in Patients with Affective Disorder: A Nested Case-Control Study [0.03%]
情感障碍患者的抗精神病药物暴露与结直肠癌风险：一项病例对照研究
Tien-Wei Hsu,Shih-Jen Tsai,Tzeng-Ji Chen et al.
Tien-Wei Hsu et al.
Background: This study aimed to assess the association between the risk of colorectal cancer (CRC) and exposure to mood stabilizers, antidepressants, and antipsychotics in patients with affective disorders. ...
How to Improve Methodological Issues in Clinical Trials to Confirm that Pentoxifylline is Useful as an Add-on Therapy for Major Depressive Disorder [0.03%]
如何改进临床试验中的方法学问题以确认氨茶碱可作为重度抑郁症的辅助治疗药物
Tainá C Ferreira,Arthur H de Alencar Quirino,Samuel C Aguiar Alves et al.
Tainá C Ferreira et al.
Impact of Parkinson Medication on Neuropsychiatric and Neurocognitive Symptoms in Patients with Advanced Parkinson Disease Prior to Deep Brain Stimulation [0.03%]
帕金森病晚期接受深部脑刺激患者使用抗帕金森药物对神经精神和神经认知症状影响的研究
Jan Haeckert,Astrid Roeh,Susanne Karch et al.
Jan Haeckert et al.
Introduction: This study evaluates the impact of Parkinson disease (PD) medication in advanced PD on neuropsychological performance, psychiatric symptoms, impulsivity and the quality of life. In the 4-year period 27 patie...
Impact of Antipsychotic Medications on Weight Gain and Eating Disorder-Related Psychopathology in Adult Inpatients with Anorexia Nervosa [0.03%]
抗精神病药物对厌食症住院成人患者体重增加和饮食障碍相关心理病理的影响
Tabea Bauman,David R Kolar,Christoph U Correll et al.
Tabea Bauman et al.
Introduction: The impact of antipsychotic use on weight gain and eating disorder-related psychopathology in adult inpatients with anorexia nervosa (AN) is unclear. ...
Activation of Hippocampal Neuronal NADPH Oxidase NOX2 Promotes Depressive-Like Behaviour and Cognition Deficits in Chronic Restraint Stress Mouse Model [0.03%]
慢性束缚应激小鼠模型中海马神经元NADPH氧化酶NOX2的激活促进抑郁样行为和认知缺陷
Zejie Zuo,Hongyang Zhang,Zhihui Li et al.
Zejie Zuo et al.
Background: Nicotinamide adenosine dinucleotide phosphate oxidases (NOX) play important roles in mediating stress-induced depression. Three NOX isotypes are expressed mainly in the brain: NOX2, NOX3 and NOX4. In this stud...
Piyumi Fernando,Johanna Strauss,Elias Wagner et al.
Piyumi Fernando et al.
Introduction: Approximately 30% of individuals with schizophrenia experience treatment resistance (TR), with 70% exhibiting it from the onset. Most research fails to distinguish between acquired and innate resistance, wit...
ABC Family Gene Polymorphisms and Cognitive Functions Interact to Influence Antidepressant Efficacy [0.03%]
五羟色胺系统基因多态性与认知功能在抗抑郁药疗效中的交互作用
Meijiang Jin,Lei Ji,Maojia Ran et al.
Meijiang Jin et al.
Introduction: The importance of identifying relevant indicators of antidepressant efficacy is highlighted by the low response rates to antidepressant treatment for depression. The ABC gene family, encoding ATP-dependent t...