Cardiac Consequences Associated with Psychedelic Use: A Systematic Review of Lysergic Acid Diethylamide, 3,4-Methylenedioxymethamphetamine, and 5-Hydroxytryptamine 2B-Mediated Valvular Heart Disease [0.03%]
与迷幻剂使用相关的的严重心脏后果：针对麦角酸二乙胺、摇头丸和血清素2B介导的心瓣膜病的系统性回顾研究
Tianyi Xu,Sabrina Wong,Gia Han Le et al.
Tianyi Xu et al.
Serotonergic psychedelics, such as lysergic acid diethylamide, and psilocybin, and the entactogen 3,4-methylenedioxymethamphetamine exhibit agonist activity at the 5-hydroxytryptamine 2B receptor, a signalling pathway known to mechanistical...
Be Aware of AI Limitations [0.03%]
谨防人工智能的局限性
Scott Monteith,Tasha Glenn,John Richard Geddes et al.
Scott Monteith et al.
The Effect of Kidney Function and Cardiovascular and Anti-Inflammatory Comedications on the Serum Concentration of Risperidone under Naturalistic Conditions [0.03%]
肾脏功能和心血管及抗炎药物对自然状态下利培酮血药浓度的影响
Meike Kohler,Jürgen Deckert,Sebastian Walther et al.
Meike Kohler et al.
Polypharmacy has an important role in psychiatry, as the kidney function can be affected by medication. Risperidone is metabolized hepatically to 9-hydroxyrisperidone and excreted renally. Here, we study how serum concentrations of risperid...
Can Red Blood Cell Membrane Fatty Acids Predict Intracellular Lithium Concentration in Bipolar Disorder? A Cross-Sectional Study [0.03%]
红细胞膜脂肪酸能预测双相情感障碍患者的锂离子 intracellular浓度吗？一项横断面研究
Monika Heng,Thomas Diot,Bruno Millet et al.
Monika Heng et al.
Bipolar disorder is a chronic psychiatric condition that requires long-term treatment. Lithium remains the gold standard for mood stabilization; yet, its therapeutic response is highly variable and unpredictable due to the lack of reliable ...
Utilizing Machine Learning to Forecast 3-Month Remission Outcomes in Bipolar Disorder Patients Treated with Lithium [0.03%]
利用机器学习预测锂治疗的双相情感障碍患者3个月缓解结局
Alessandro Cuomo,Despoina Koukouna,Simone Pardossi et al.
Alessandro Cuomo et al.
Lithium remains a first-line mood stabilizer for bipolar disorder; yet, only a subset of patients achieves symptomatic remission. Early prediction of treatment response could guide personalized management. In this study, we leveraged machin...
Therapeutic Reference Ranges for ADHD Drugs in Blood of Children and Adolescents: A Systematic Review by the AGNP TDM-Task Force [0.03%]
儿童和青少年ADHD药物治疗的血药浓度参考范围系统评价：AGNP TDM工作组报告
Sarah S Hagenkötter,Karin Egberts,Stefanie Fekete et al.
Sarah S Hagenkötter et al.
Attention deficit-/hyperactivity disorder (ADHD) medications are commonly prescribed to children and adolescents, but therapeutic reference ranges have not been systematically evaluated yet. This study aimed to establish preliminary therape...
Antipsychotic Polypharmacy and Epigenetic Age Acceleration in Schizophrenia [0.03%]
抗精神病药物多药治疗与精神分裂症表观遗传年龄加速的关系
George Nader,Adrian Yung,Yuyang Liang et al.
George Nader et al.
Schizophrenia spectrum disorders (SSD) are debilitating psychiatric illnesses that require extensive pharmacologic, cognitive, and functional management. SSD patients are often prescribed different medications, most commonly antipsychotics,...
The Endocannabinoid System in PTSD: Molecular Targets for Modulating Fear and Anxiety [0.03%]
PTSD中的内源大麻素系统：调节恐惧和焦虑的分子靶点
Stanley Lyndon
Stanley Lyndon
Fear and anxiety perform essential protective roles, yet when they become dysregulated, they can trap trauma survivors in persistent hypervigilance and distress. Post-traumatic stress disorder (PTSD) manifests as intrusive memories, avoidan...
Are Intravenous Subnarcotic Ketamine Infusions as an Adjunct Treatment for Treatment-Resistant Depression Ready to be Recommended in European Guidelines? [0.03%]
亚硝酸盐静脉注射氯胺酮作为难治性抑郁障碍的辅助治疗，是否可以被推荐为欧洲指南中的标准疗法？
Udo Bonnet,Norbert Scherbaum,Georg Juckel et al.
Udo Bonnet et al.
Association of Physical Activity and Bone Mineral Density in Adults with Depressive Symptoms [0.03%]
抑郁症成年人中身体活动与骨密度的关系
Shakila Meshkat,Qiaowei Lin,Vanessa K Tassone et al.
Shakila Meshkat et al.
Depression affects a significant proportion of adults in the United States. Studies exploring the association between depression and bone mineral density (BMD) have shown mixed results. Moreover, the relationship between BMD and physical ac...