Memantine versus Ginkgo biloba Extract: A Comparative Study on Cognitive Dysfunction Treatment in a Novel Rat Model [0.03%]
美金刚与银杏叶提取物的对比研究:在新型大鼠模型中对认知障碍进行治疗
Essmat A H Allam,Abdel-Azim Assi,Dalia M Badary et al.
Essmat A H Allam et al.
Extracellular senile plaques and intraneuronal neurofibrillary tangles are two devastating brain proteinopathies that are indicative of Alzheimer's disease, the most prevalent type of dementia. Currently, no effective medications are availa...
Vasorelaxant effects of ellagitannins isolated from Cuphea carthagenensis [0.03%]
从Cuphea carthagenensis中分离的五倍子单宁的血管舒张作用
Kaori Katiuska Yamaguchi Isla,Mirtes Midori Tanae,Maria Teresa Riggio de Lima-Landman et al.
Kaori Katiuska Yamaguchi Isla et al.
Cuphea carthagenensis (Jacq.) J. F. Macbr. is a popular plant in Brazilian folk medicine owing to its hypotensive and central nervous system depressant effects. This study aimed to validate the hypotensive effect of the plant's aqueous extr...
Antiproliferative and Antitelomerase Effects of Silymarin on Human Colorectal and Hepatocellular Carcinoma Cells [0.03%]
奶蓟素对人结肠直肠癌和肝细胞 carcinoma 细胞的抗增殖及抗端粒酶作用效果
Daruosh Rahimi,Roya Sharifi,Hajar Jaberie et al.
Daruosh Rahimi et al.
Silymarin, a widely-used hepatoprotective agent, has shown antitumor properties in both in vitro and animal studies. Currently, there is limited knowledge regarding silymarin's antitelomerase effects on human colorectal cancer and hepatocyt...
Purification, Molecular Docking and Cytotoxicity Evaluation of Bioactive Pentacyclic Polyhydroxylated Triterpenoids from Salvia urmiensis [0.03%]
萨尔维亚乌米叶尼种五环三萜类化合物的纯化,分子对接和细胞毒性评价
Mahdi Moridi Farimani,Mahdi Abbas-Mohammadi,Samira Ghorbannia-Dellavar et al.
Mahdi Moridi Farimani et al.
Triterpenoids, as one of the largest classes of naturally occurring secondary metabolites in higher plants, are of interest due to their high structural diversity and wide range of biological activities. In addition to several promising pha...
Affinin, Isolated from Heliopsis longipes, Induces an Antihypertensive Effect That Involves CB1 Cannabinoid Receptors and TRPA1 and TRPV1 Channel Activation [0.03%]
来自长脚紫松果菊的Affinin通过CB1大麻素受体和TRPA1及TRPV1通道活化诱导抗高血压作用
Beatriz A Luz-Martínez,Dailenys Marrero-Morfa,Francisco J Luna-Vázquez et al.
Beatriz A Luz-Martínez et al.
In previous studies, we demonstrated that the ethanolic extract of Heliopsis longipes roots and its main alkamide, affinin, elicit a vasorelaxant effect through a mechanism involving activation of the gasotransmitter pathways and stimulatio...
Toxins in Botanical Drugs and Plant-derived Food and Feed - from Science to Regulation: A Workshop Review [0.03%]
植物药物和植物来源的食品及饲料中的毒素-从科学研究到法规制定:一次研讨会报告
Dieter Schrenk,Ashley Allemang,Jörg Fahrer et al.
Dieter Schrenk et al.
In September 2022, the 3rd International Workshop on pyrrolizidine alkaloids (PAs) and related phytotoxins was held on-line, entitled 'Toxins in botanical drugs and plant-derived food and feed - from science to regulation'. The workshop foc...
A New Blend of Litsea cubeba, Pinus mugo, and Cymbopogon winterianus Essential Oil Active as an Anti-tyrosinase Ingredient in Topical Formulations [0.03%]
一种新的月桂叶、欧洲赤松和细籽香茅混合精油,具有 topical formulations中的抗酪氨酸酶成分活性
Francesca Capetti,Cecilia Cagliero,Monica Argenziano et al.
Francesca Capetti et al.
Tyrosinase is a target enzyme to be inhibited in order to reduce excessive melanin production and prevent typical age-related skin disorders. Essential oils are complex mixtures of volatile compounds, belonging mainly to monoterpenoids and ...
Dendropanoxide Attenuates High Glucose-induced Oxidative Damage in NRK-52E Cells via AKT/mTOR Signaling Pathway [0.03%]
毛钩藤碱通过AKT/mTOR信号通路对抗高糖引起的肾元细胞氧化损伤作用研究
Song Hee Lee,Ju Ri Kim,Joo Kyung Shin et al.
Song Hee Lee et al.
Hyperglycemia is a potent risk factor for the development and progression of diabetes-induced nephropathy. Dendropanoxide (DPx) is a natural compound isolated from Dendropanax morbifera (Araliaceae) that exerts various biological effects. H...
Janice Sue Wen Chan,Xin Yi Lim,Norfarahana Japri et al.
Janice Sue Wen Chan et al.
Zingiber zerumbet, a plant native to tropical and subtropical Asia, has a vast range of traditional uses and has been continuously studied for its medicinal properties. However, a systematic methodological approach in evidence synthesis on ...
Polyphenols, Antioxidants, and Wound Healing of Lecythis pisonis Seed Coats [0.03%]
聚酚、抗氧化剂和Lecythis pisonis种子皮的伤口愈合效应
Elisângela Flávia Pimentel,Bruno Gomes de Oliveira,Ana Claudia Hertel Pereira et al.
Elisângela Flávia Pimentel et al.
To better use the Lecythis pisonis Cambess. biomass, this study investigates whether Sapucaia seed coats present wound healing properties. We analyzed the antibacterial, antioxidant, and wound healing-promoting potentials, plus cytotoxicity...