Real-World Data to Document the Use of Herbal Medicinal Products in Children - Report of a Workshop in Krakow [0.03%]
关于儿童草药药品真实世界使用的数据记录研究报告（克拉科夫研讨会报告）
Nico Symma,Andreas Hensel,Bernd Roether et al.
Nico Symma et al.
The workshop "Real-world data to document the use of phytopharmaceuticals in children" was organized by the GA Foundation Plants for Health in collaboration with multiple international scientific societies on July 14, 2024, during the Inter...
Galactomannan and vicilin from fenugreek seeds (Trigonella foenum-graecum) impair pathogen-host interaction of Campylobacter jejuni with intestinal cells via JlpA [0.03%]
黄芪种子的半乳甘露聚糖和vicilin通过JlpA削弱Campylobacter jejuni与肠细胞的相互作用
Leon Kemper,Fabian Herrmann,Simone König et al.
Leon Kemper et al.
Campylobacter jejuni is the leading cause of severe enteritis worldwide. Identification of natural products against C. jejuni, inhibiting early-stage host-pathogen interactions is a promising strategy, particularly by blocking bacterial adh...
The Characteristics and Functions of Orally Absorbed Herbal Decoction-borne Plant MicroRNAs [0.03%]
口服汤剂递送的植物来源microRNA的特征及功能学研究
Yating Zhu,Yao Jia,Yicheng Yu et al.
Yating Zhu et al.
Herbal decoctions always contain numerous plant microRNAs (miRNAs), and some of these can be absorbed orally to exert cross-kingdom gene regulation. However, little is known about which specific types of herbal decoction-borne plant miRNAs ...
Eleutherococcus senticosus Alleviates Aristolochic-Acid-Induced Acute Kidney Damage by Inhibiting the NLRP3/IL-1β Signaling Pathway in Mice [0.03%]
辽术通过抑制NLRP3/IL-1β信号通路缓解马兜铃酸致小鼠急性肾损伤
Jian-Hui Zhang,Mei-Zhu Gao,Qian Chen et al.
Jian-Hui Zhang et al.
Eleutherococcus senticosus (ES) exerts various pharmacological effects, including renoprotection in a rat model of renal ischemia-reperfusion injury. However, the mechanisms of these effects remain unclear. Therefore, we investigated the ef...
Characterization of lipophilicity and blood partitioning of pyrrolizidine alkaloids and their N-oxides in vitro and in silico for toxicokinetic modeling [0.03%]
基于体外和计算机模拟的吡咯里西啶生物碱及其N氧化物的亲脂性和血液分配表征以建立毒代动力学模型
Anja Lehmann,Manuel Haas,Julian Taenzer et al.
Anja Lehmann et al.
Lipophilicity and blood partitioning are important determinants for predicting toxicokinetics using physiologically-based toxicokinetic (PBTK) modeling. In this study, the logarithm of the n-octanol:water partition coefficient (logP) and th...
Combating inflammation and oxidative stress: Exploring the cellular effects of Lonicera caerulea var. kamtschatica extract [0.03%]
抗炎和抗氧化：探讨越桔提取物的细胞效应
Katarzyna Zima,Laura Banaszkiewicz,Mateusz Kacper Woźniak et al.
Katarzyna Zima et al.
Lonicera caerulea var. kamtschatica (LCK), known as blue honeysuckle or haskap berry, is rich in bioactive compounds such as polyphenols, flavonoids, and anthocyanins, which are linked to various health benefits, including anti-inflammatory...
Application of Network Pharmacology in the Treatment of Neurodegenerative Diseases with Traditional Chinese Medicine [0.03%]
网络药理学在中医药治疗神经退行性疾病中应用研究
Qiang Chen,Guanghui Chen,Qianyan Wang
Qiang Chen
In recent years, the incidence of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis, has shown a steadily rising trend, which has posed a major challenge to...
Monotherapy or combination therapy of Oleanolic acid? From therapeutic significance and drug delivery to clinical studies: A comprehensive review [0.03%]
单用或联合用药？从药效和药物输送至临床研究的全面综述——橄榄酸的功效评估
Md Adil Shaharyar,Tanmoy Banerjee,Monalisha Sengupta et al.
Md Adil Shaharyar et al.
Oleanolic acid (OA) is a pentacyclic triterpenoid molecule widely distributed throughout medicinal plants. This naturally occurring OA has attracted considerable interest due to its wide range of pharmacological characteristics, notably its...
Curcumin: Epigenetic Modulation and Tumor Immunity in Antitumor Therapy [0.03%]
姜黄素通过表观遗传调控和肿瘤免疫的抗肿瘤机制研究进展
Xin Wan,Dong Wang
Xin Wan
Curcumin is the main ingredient of the Chinese herbal turmeric rhizome, used to treat tumors, diabetes, inflammation, neurodegenerative diseases, cardiovascular diseases, metabolic syndrome, and liver diseases. The antitumor effects of curc...
Comprehensive Biotechnological Strategies for Podophyllotoxin Production from Plant and Microbial Sources [0.03%]
来自植物和微生物来源的汉防己甲素综合生物技术策略
Anviksha Anviksha,M S Reddy
Anviksha Anviksha
Podophyllotoxin is derived from plant sources and exhibits strong anticancer activity. However, limited natural availability and environmental impacts from traditional extraction methods drive the search for alternative production approache...