Effectiveness and safety of ravulizumab for Japanese patients with atypical hemolytic uremic syndrome switched from eculizumab: an analysis of a post-marketing surveillance [0.03%]
艾库西姆单抗治疗的日本补体介导的非典型溶血尿毒综合征患者的拉奴珠单抗转换为 ravulizumab 的有效性和安全性:上市后监测分析
Shuichi Ito,Hiroshi Hataya,Masanori Matsumoto et al.
Shuichi Ito et al.
Background: Ravulizumab, a long-acting anti-C5 antibody, was approved for atypical hemolytic uremic syndrome (aHUS) in September 2020 in Japan. Post-marketing surveillance was mandated by local regulatory authorities to e...
Machine learning using serial changes in proteinuria during initial steroid therapy to predict treatment response and immunosuppressant use in pediatric idiopathic nephrotic syndrome [0.03%]
基于初始糖皮质激素治疗期间蛋白尿的连续变化利用机器学习预测儿童原发性肾病综合征患者的治疗反应及免疫抑制剂的应用
Takaya Iida,Kenichiro Miura,Takayuki Okamoto et al.
Takaya Iida et al.
Background: Epidemiological studies on idiopathic nephrotic syndrome (INS) in children have identified no definitive factors predicting steroid-resistant nephrotic syndrome (SRNS) or frequent relapsing nephrotic syndrome....
The epidemiology of encapsulating peritoneal sclerosis in an era of biocompatible neutral peritoneal dialysis solution in Japan [0.03%]
日本生物相容性中性腹膜透析液时代包裹性腹膜硬化症的流行病学特征
Yukio Maruyama,Nanae Matsuo,Yudo Tanno et al.
Yukio Maruyama et al.
Background: Encapsulating peritoneal sclerosis (EPS) is one of the most serious complications of peritoneal dialysis (PD). Although the incidence and severity of EPS are said to have decreased with the widespread adoption...
Pathophysiology and causes of hyperkalemia: unraveling causes beyond kidney dysfunction [0.03%]
高钾血症的发病机制及病因:揭开肾脏功能障碍之外的原因
Takuya Fujimaru,Kazuhito Hirose,Masahiko Yazawa et al.
Takuya Fujimaru et al.
This review article series on water and electrolyte disorders is based on the "Electrolyte Winter Seminar" that is held annually for young nephrologists in Japan. This seminar includes lively discussions based on cases, which have been part...
Potential involvement of abnormal splicing in severe WT1-related disorders [0.03%]
WT1相关严重疾病中异常剪接的潜在作用
China Nagano,Masafumi Matuso,Yuta Inoki et al.
China Nagano et al.
Introduction: WT1-related disorders are associated with WT1 gene variants. Recent advances in genetic medicine have led to a better understanding of the genotype-phenotype correlation in WT1-related diseases, particularly...
Whole slide imaging for rapid treatment decision-making and education in renal pathology [0.03%]
基于肾脏病理的全切片数字化快速诊疗和教学实践
Emiko Otsuka,Mineaki Kitamura,Kiyokazu Tsuji et al.
Emiko Otsuka et al.
Background: Whole slide imaging (WSI) is digital imaging technique that involves scanning glass slides. Although WSI is widely used in pathological diagnosis and education, its impact on nephrology education remains unkno...
Long-term prognosis of pure membranous lupus nephritis: a comparison with proliferative lupus nephritis in Japan [0.03%]
日本原发性膜性狼疮肾炎的长期预后与增生型狼疮肾炎的比较
Hidekazu Ikeuchi,Yoichi Imai,Shoichi Maruyama et al.
Hidekazu Ikeuchi et al.
Background: Membranous lupus nephritis (MLN), a distinct subtype of lupus nephritis (LN), is generally associated with more favorable outcomes than proliferative LN (PLN). However, clinical data regarding pure MLN are lim...
Evaluation of an educational program for community pharmacists involved in pharmacotherapy for patients with impaired renal function: a preliminary study [0.03%]
社区药房药师参与肾功能不全患者药物治疗教育项目效果评价:一项初步研究
Akio Inoue,Yuki Kondo,Tomoko Kondo et al.
Akio Inoue et al.
Background: Inquiries by community pharmacists to physicians regarding prescriptions for patients with impaired renal function are an important part of pharmaceutical care. However, such inquiries remain infrequent in Jap...
Internal iliac artery calcification score predicts cardiovascular disease and mortality following living-donor kidney transplantation [0.03%]
髂内动脉钙化积分可预测活体供肾移植术后的冠心病和死亡风险
Mitsuru Tomizawa,Shunta Hori,Kuniaki Inoue et al.
Mitsuru Tomizawa et al.
Background: Cardiovascular disease remains a significant cause of death in kidney transplant recipients. While several studies have demonstrated the association of aortoiliac calcification with cardiovascular disease and ...