Early warning of drug-induced cardiotoxicity: quantitative determination of Mfn2 biomarker via electrochemical immunosensing technology [0.03%]
基于电化学生物传感技术的线粒体融合蛋白-2标志物定量检测及其在药物心脏毒性早期预警中的应用研究
Zixia Wang,Mian Chen,Diaoguo Li et al.
Zixia Wang et al.
Drug-induced cardiotoxicity (DIC) poses a significant challenge in both drug development and clinical practice, Making early and accurate assessment crucial. Existing studies have shown that mitochondrial fusion mediated by mitochondrial fu...
Si@D(AuPt) nanozyme-driven point-of-care testing technology for real-time monitoring of clinical urinary-related indicators [0.03%]
用于临床实时监测尿液相关指标的Si@D(AuPt)纳米酶驱动型POCT技术
Guangmin Cheng,Wenlong Bai,Xuanming Zhang et al.
Guangmin Cheng et al.
To address the challenges of poor system compatibility, low sensitivity, and narrow detection range in traditional colorimetric lateral flow immunochromatographic assay (LFA) for dynamic monitoring of urinary tract infection (UTI) pathogens...
Current advances in multi-strategy collaborative sensitization for self-powered electrochemical biosensors and their applications in disease biomarker detection [0.03%]
自供电电化学生物传感器多策略协同敏化的最新进展及在疾病标志物检测中的应用研究
Yong-Ping Gao,Meng Zeng,Ke-Jing Huang et al.
Yong-Ping Gao et al.
Self-powered electrochemical biosensors have emerged as a cutting-edge direction in disease biomarker detection due to their miniaturization potential and external power-free characteristics. Enzymatic biofuel cell-based self-powered biosen...
A smartphone-integrated portable colorimetric sensing platform for ascorbic acid based on a PtAu@Rh nanozyme with high specific activity [0.03%]
一种基于高活性PtAu@Rh纳米酶的便携式智能手机集成色度传感平台用于检测维生素C
Jian Hao,Xiaojie Dong,Zeyang Yu et al.
Jian Hao et al.
A PtAu@Rh nanozyme with strong peroxidase (POD)-like activity was synthesized via the template method, and a colorimetric sensing platform for ascorbic acid (AA) detection based on UV‒vis or smartphone assistance was established. The resul...
Label-free HCR-facilitated nanozyme catalysis and fluorescence simultaneous amplification for ultrasensitive dual-signal sensing of foodborne Salmonella typhimurium [0.03%]
一种新颖的无标记信号增强策略用于沙门氏菌的超灵敏双重信号传感检测技术
Fengxia Zhao,Shiyu Jia,Hangli Yan et al.
Fengxia Zhao et al.
A label-free hybridization chain reaction (HCR)-facilitated nanozyme catalysis and fluorescence simultaneous amplification strategy is proposed for the ultrasensitive fluorescence-colorimetric dual-mode detection of S. typhimurium in comple...
Advancing green chemistry for the sensitive and selective detection of N-nitrosodiethylamine (NDEA) monitoring: the role of nanomaterial-embedded electropolymerized molecularly imprinted polymer-based sensors [0.03%]
用于监测亚硝基二乙胺(NDEA)的敏感和选择性检测的绿色化学研究：纳米材料嵌入式电聚合分子印迹聚合物传感器的作用
Nimisha Jadon,Ahmet Cetinkaya,Sena Piskin et al.
Nimisha Jadon et al.
N-Nitrosodiethylamine (NDEA), a potent carcinogen with an acceptable intake (AI) of 26.5 ng/day, poses a significant health risk, necessitating accurate detection and quantification. Here, we introduce the first-ever molecularly imprinted p...
ZIF-8-derived double-shelled hollow ZnS nanocages: a new signal transducer for photoelectrochemical immunoassay of neuron-specific antigen-based neuroblastoma biomarker [0.03%]
用于神经母细胞瘤生物标志物的神经元特异性抗原的光电化学免疫测定的新信号转换器：ZIF-8衍生的双壳空心ZnS纳米笼
Zhaobin Zeng,Haibin Wang,Chongming Cai et al.
Zhaobin Zeng et al.
Methods based on photoelectrochemical immunoassay have been utilized for the quantitative monitoring of neuron-specific antigen (NSE) with neuroblastoma patients, but most provide only low sensitivity. In this contribution, a simple and fea...
Development of a water-soluble polarity/reactive nitrogen species dual-responsive fluorescence probe with enhanced specificity/sensitivity for early-stage non-alcoholic fatty liver disease diagnosis [0.03%]
一种用于早期诊断非酒精性脂肪肝病的水溶性极性和反应性氮物种双响应荧光探针的发展
Haiping Wang,Li Luo,Feifei Han et al.
Haiping Wang et al.
Non-alcoholic fatty liver disease (NAFLD) is a global health concern, but early diagnosis remains challenging due to the limitations of current methods, which are often invasive or lack sensitivity. To address this, we developed UIO-YB, a d...
An all-in-one assay for bacteria-related detections through gold nanoparticles-amplified electrical conductivity [0.03%]
基于金纳米粒子电导放大作用的一滴血细菌检测法
Shicheng Su,Jing Hu,Yichun Zhu et al.
Shicheng Su et al.
An all-in-one assay based on the electrical conductivity (EC) has been developed that enables the viability test and the specific detection of pathogenic bacteria, including the differentiation of (1) live/dead bacteria, (2) drug-sensitive/...
Disposable paper-based electrochemical sensor for hydroquinone detection in environmental samples using a MXene-CNT hybrid composite [0.03%]
一种基于MXene和CNT混合材料的纸基电化学生物传感器用于环境样本中对苯二酚的检测
Pramod K Kalambate,Sharad S Upadhyay,Shambhavi Singh et al.
Pramod K Kalambate et al.
This study investigates the electrochemical performance of MXene/multi-walled carbon nanotubes (MWCNT) composite-based sensor and its comparison with MWCNT for the sensitive detection of hydroquinone (HQ) in undiluted water samples. The sen...