Comparison of the effects of 12 months of monthly minodronate monotherapy and monthly minodronate combination therapy with vitamin K2 or eldecalcitol in patients with primary osteoporosis [0.03%]
利塞膦酸单药与联合维生素K2或艾地骨化醇治疗绝经后女性及老年男性1年的疗效比较：一项多中心、前瞻性研究
Kosuke Ebina,Takaaki Noguchi,Makoto Hirao et al.
Kosuke Ebina et al.
The aim of this observational, nonrandomized study was to compare the effects of 12 months of monthly minodronate (MIN; 50 mg/month) monotherapy and MIN combination therapy with vitamin K2 (VK; 45 mg/day) or eldecalcitol (ELD; 0.75 μg/day)...
Intermittent PTH treatment can delay the transformation of mature osteoblasts into lining cells on the periosteal surfaces [0.03%]
间歇性PTH治疗可延缓成熟骨形成细胞向骨内膜盖细胞的转化
Mi-Gyeong Jang,Ji Yeon Lee,Jae-Yeon Yang et al.
Mi-Gyeong Jang et al.
Mature osteoblasts have three fates: as osteocytes, quiescent lining cells, or osteoblasts that undergo apoptosis. However, whether intermittent parathyroid hormone (PTH) can modulate the fate of mature osteoblasts in vivo is uncertain. We ...
Important abnormalities of bone mineral metabolism are present in patients with coronary artery disease with a mild decrease of the estimated glomerular filtration rate [0.03%]
冠状动脉疾病患者肾小球滤过率轻度下降时骨矿物质代谢异常增多
Emilio González-Parra,Álvaro Aceña,Óscar Lorenzo et al.
Emilio González-Parra et al.
Chronic kidney disease (CKD)-mineral and bone disorder (MBD) is characterized by increased circulating levels of parathormone (PTH) and fibroblast growth factor 23 (FGF23), bone disease, and vascular calcification, and is associated with ad...
Regulation of renal phosphate handling: inter-organ communication in health and disease [0.03%]
肾脏磷酸盐处理的调节：健康与疾病的器官间通讯
Sawako Tatsumi,Atsumi Miyagawa,Ichiro Kaneko et al.
Sawako Tatsumi et al.
In this review, we focus on the interconnection of inorganic phosphate (Pi) homeostasis in the network of the bone-kidney, parathyroid-kidney, intestine-kidney, and liver-kidney axes. Such a network of organ communication is important for b...
Association between bone indices assessed by DXA, HR-pQCT and QCT scans in post-menopausal women [0.03%]
绝经后女性DXA、HR-pQCT和QCT骨指标间的相关性分析
Anne Kristine Amstrup,Niels Frederik Breum Jakobsen,Emil Moser et al.
Anne Kristine Amstrup et al.
Quantitative computed tomography (QCT), high-resolution peripheral QCT (HR-pQCT) and dual X-ray absorptiometry (DXA) scans are commonly used when assessing bone mass and structure in patients with osteoporosis. Depending on the imaging tech...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2016 Nov;34(6):638-645. DOI:10.1007/s00774-015-0708-9 2016
Association between Helicobacter pylori infection and osteoporosis: a systematic review and meta-analysis [0.03%]
幽门螺杆菌感染与骨质疏松症的相关性：系统评价和meta分析
Sikarin Upala,Anawin Sanguankeo,Karn Wijarnpreecha et al.
Sikarin Upala et al.
Characterization of an acromesomelic dysplasia, Grebe type case: novel mutation affecting the recognition motif at the processing site of GDF5 [0.03%]
一种新型GDF5处理位点识别基序变异导致的Grebe型肢端骨骼发育不全症病例分析
Monica Martinez-Garcia,Eva Garcia-Canto,Maria Fenollar-Cortes et al.
Monica Martinez-Garcia et al.
Acromesomelic dysplasia, Grebe type is a very rare skeletal dysplasia characterized by severe dwarfism with marked micromelia and deformation of the upper and lower limbs, with a proximodistal gradient of severity. CDMP1 gene mutations have...
Association between vitamin D status and serum parathyroid hormone concentration and calcaneal stiffness in Japanese adolescents: sex differences in susceptibility to vitamin D deficiency [0.03%]
日本青少年维生素D缺乏的性别差异易感性：与血清甲状旁腺激素浓度和跟骨僵硬性的关联性研究
Naoko Tsugawa,Kazuhiro Uenishi,Hiromi Ishida et al.
Naoko Tsugawa et al.
There is currently insufficient information on serum 25-hydroxyvitamin D (25OHD) and parathyroid hormone (PTH) concentrations, and bone mineral status in healthy adolescents to allow reference values to be set. This study aimed to provide c...
The association between vitamin D and parathyroid hormone and bone mineral density: the Dong-gu Study [0.03%]
维生素D和甲状旁腺激素与骨密度的关系：东区研究
Seong-Woo Choi,Sun-Seog Kweon,Jin-Su Choi et al.
Seong-Woo Choi et al.
The primary objective of the present study was to investigate the relationship between 25-hydroxyvitamin D (25[OH]D) and areal bone mineral density (aBMD) in Korean subjects from the general population aged ≥50 years. This study included 8...
Collagen production of osteoblasts revealed by ultra-high voltage electron microscopy [0.03%]
超高压电子显微镜观察成骨细胞的胶原合成
Rumiko Hosaki-Takamiya,Mana Hashimoto,Yuichi Imai et al.
Rumiko Hosaki-Takamiya et al.
In the bone, collagen fibrils form a lamellar structure called the "twisted plywood-like model." Because of this unique structure, bone can withstand various mechanical stresses. However, the formation of this structure has not been elucida...