The effects of switching daily teriparatide to oral bisphosphonates or denosumab in patients with primary osteoporosis [0.03%]
特立帕肽换用阿仑膦酸钠或地诺单抗治疗绝经后妇女骨质疏松症患者的疗效及安全性研究
Kosuke Ebina,Jun Hashimoto,Masafumi Kashii et al.
Kosuke Ebina et al.
The aim of this 12-month, observational study was to compare the effects of switching daily teriparatide (TPTD) to oral bisphosphonates (BP) therapy or denosumab (DMAb) therapy in patients with primary osteoporosis. Patients [n = 78; 71 pos...
Preventive effects of raloxifene treatment on agerelated weight loss in postmenopausal women [0.03%]
雷洛昔芬治疗对绝经后妇女年龄相关性体重下降的预防作用
Tomohiko Urano,Masataka Shiraki,Tatsuhiko Kuroda et al.
Tomohiko Urano et al.
Decline of body weight and body mass index (BMI) with aging is a major risk factor for osteoporosis and fracture, suggesting that treatment for osteoporosis may affect body composition. However, the effects of treatment for osteoporosis on ...
Jinqiao Li,Hongyu Zhang,Chao Yang et al.
Jinqiao Li et al.
An increasing amount of data indicate that osteocalcin is an endocrine hormone which regulates energy metabolism, male fertility and brain development. However, the detailed functions and mechanism of osteocalcin are not well understood and...
Bone mineral density and its determinants in men with opioid dependence [0.03%]
阿片类药物依赖男性患者的骨密度及其影响因素
Frank Gotthardt,Christine Huber,Clara Thierfelder et al.
Frank Gotthardt et al.
Data on the influence of opioid substitution therapy (OST) on skeletal health in men is limited. This cross-sectional study aimed to determine the prevalence of low bone mass in male drug users and to evaluate the relationship between endog...
Characterization and comparison of osteoblasts derived from mouse embryonic stem cells and induced pluripotent stem cells [0.03%]
来源于小鼠胚胎干细胞和诱导多能干细胞的成骨细胞的特征及比较分析
Ming-San Ma,Vishnu Kannan,Anneriek E de Vries et al.
Ming-San Ma et al.
New developments in stem cell biology offer alternatives for the reconstruction of critical-sized bone defects. One of these developments is the use of induced pluripotent stem (iPS) cells. These stem cells are similar to embryonic stem (ES...
Comparative Study
Journal of bone and mineral metabolism. 2017 Jan;35(1):21-30. DOI:10.1007/s00774-015-0730-y 2017
Serum pentosidine concentration is associated with radiographic severity of lumbar spondylosis in a general Japanese population [0.03%]
血清戊糖啶浓度与日本一般人群腰椎骨关节病的放射学严重程度有关
Daisuke Chiba,Kanichiro Wada,Toshihiro Tanaka et al.
Daisuke Chiba et al.
The aim of this study was to investigate the relationship between the radiographic severity of lumbar spondylosis (LS) and serum bone metabolic markers. A total of 681 individuals volunteered for this study (269 men, 412 women; age: 54.9 ±...
Visfatin is a positive predictor of bone mineral density in young survivors of acute lymphocytic leukemia [0.03%]
visfatin是急性淋巴细胞白血病年轻幸存者骨矿密度的阳性预测因素
Adriana Aparecida Siviero-Miachon,Angela Maria Spinola-Castro,Maria Lucia de Martino Lee et al.
Adriana Aparecida Siviero-Miachon et al.
Bone mass acquisition may be compromised in survivors of childhood acute lymphocytic leukemia due to various factors, including adiposity. Fat accumulation can affect bone through the direct effect of adipokines or indirectly through the st...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2017 Jan;35(1):73-82. DOI:10.1007/s00774-015-0728-5 2017
The role of serum total and free 25-hydroxyvitamin D and PTH values in defining vitamin D status at the end of winter: a representative survey [0.03%]
冬季结束时定义维生素D状态的血清总25-羟基维生素D、游离25-羟基维生素D和PTH值的作用:一项代表性的调查研究
Boglárka Szabó,Ádám G Tabák,Erzsébet Toldy et al.
Boglárka Szabó et al.
We sought the lowest serum total 25-hydroxyvitamin D (t-25OHD) values in geographic areas with four seasons and investigated whether the calculation of serum free 25-hydroxyvitamin D (f-25OHD) could provide additional information on vitamin...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2017 Jan;35(1):83-90. DOI:10.1007/s00774-015-0729-4 2017
Real-world clinical and economic outcomes for daily teriparatide patients in Japan [0.03%]
特立帕肽治疗日本患者的临床及经济结果分析
Russel Burge,Masayo Sato,Tomoko Sugihara
Russel Burge
A large medical and pharmacy claims database was used to evaluate outcomes in daily teriparatide (D-TPD) patients in Japan. 445 patients were identified (April 2008-July 2013) with 6+ months' pre- and 18+ months' post-index observation. D-T...
Effect of monthly intravenous ibandronate injections on vertebral or non-vertebral fracture risk in Japanese patients with high-risk osteoporosis in the MOVER study [0.03%]
日本MOVER研究中高强度骨松患者静脉注射伊班磷酸钠对椎体和非椎体骨折风险的影响
Masako Ito,Masato Tobinai,Seitaro Yoshida et al.
Masako Ito et al.
We examined the efficacy of intravenous (IV) ibandronate 1 mg/month in patient subgroups in the phase III MOVER study. Here we present results of analyses on the incidence of fractures in patients with prevalent vertebral fractures (1 or ≥...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2017 Jan;35(1):58-64. DOI:10.1007/s00774-015-0723-x 2017