Cortical bone analysis in a predialysis population: a comparison with a dialysis population [0.03%]
透析前受试者皮质骨分析与透析患者比较研究
Catarina Carvalho,J Magalhães,R Neto et al.
Catarina Carvalho et al.
This study was designed to characterize cortical bone by histomorphometry in a predialysis population, to correlate turnover, mineralization, and volume between cortical and trabecular bone, and to compare the findings with those in patient...
Local delivery of recombinant human FGF7 enhances bone formation in rat mandible defects [0.03%]
rhFGF7局部给药能促进大鼠下颌骨缺损的骨再生
Sher Bahadur Poudel,Govinda Bhattarai,Jae-Hwan Kim et al.
Sher Bahadur Poudel et al.
Fibroblast growth factor 7 (FGF7) plays an important role in regulating the proliferation, migration, and differentiation of cells. However, the role of FGF7 in bone formation is not yet fully understood. We examined the effect of FGF7 on b...
Vitamin K homologs as potential biomarkers for disease activity in patients with rheumatoid arthritis [0.03%]
维生素K类似物可作为类风湿性关节炎患者疾病活动性的潜在生物标志物
Hani M Khojah,Sameh Ahmed,Mahran S Abdel-Rahman et al.
Hani M Khojah et al.
The aim of this study was to evaluate the possible role of vitamin K homologs as potential biomarkers for disease activity in patients with rheumatoid arthritis (RA). In this study, 42 patients with RA and 40 healthy controls were enrolled....
Lithium chloride enhances bone regeneration and implant osseointegration in osteoporotic conditions [0.03%]
氯化锂能增强骨质疏松条件下的骨再生和种植体骨结合
Yifan Jin,Lihua Xu,Xiaohui Hu et al.
Yifan Jin et al.
Osteoporotic patients have a high risk of dental and orthopedic implant failure. Lithium chloride (LiCl) has been reported to enhance bone formation. However, the role of LiCl in the success rate of dental and orthopedic implants in osteopo...
The safety and effectiveness profile of eldecalcitol in a prospective, post-marketing observational study in Japanese patients with osteoporosis: interim report [0.03%]
依降钙素治疗骨质疏松症的日本患者前瞻性上市后观察性研究的安全性和有效性：中期报告
Hitoshi Saito,Hiroyuki Kakihata,Yosuke Nishida et al.
Hitoshi Saito et al.
This large-scale post-marketing surveillance study was conducted to assess the safety and effectiveness of eldecalcitol treatment in patients with osteoporosis in a Japanese clinical setting. A total of 3567 patients with osteoporosis were ...
Observational Study
Journal of bone and mineral metabolism. 2017 Jul;35(4):456-463. DOI:10.1007/s00774-016-0779-2 2017
Young-Kyun Lee,Jae-Suk Chang,Yong-Ki Min et al.
Young-Kyun Lee et al.
Inadequate calcium and vitamin D intake is a possible risk factor of osteoporosis. Our purposes were to estimate calcium and vitamin D intake in Korean women, and to determine associated risk factors for low calcium and vitamin D intake. Th...
4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress [0.03%]
苯甲酸预防糖皮质激素诱导的骨髓基质细胞向成骨细胞分化过程中的内质网应激和成骨细胞凋亡
Jianhui Yang,Qiong Wu,Jianguo Lv et al.
Jianhui Yang et al.
Apoptosis of osteoblasts triggered by high-dose glucocorticoids (GCs) has been identified as a major cause of osteoporosis. However, the molecular mechanisms underlying GC-induced osteoporosis remain elusive. This study was conducted to mak...
Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral density and body composition in Chinese male nuclear families [0.03%]
METTL21C基因的SNPs和单倍型与中国男性核家庭骨峰值密度及体质成分的关系
Fei Zhao,Li-Hong Gao,Shan-Shan Li et al.
Fei Zhao et al.
The methyltransferase-like 21C gene (METTL21C), which is mainly expressed in muscle, can promote the differentiation of myoblasts to myotubes and reduce glucocorticoid-induced apoptosis of osteocytes. The purpose of this study was to explor...
Platelet-derived growth factor BB enhances osteoclast formation and osteoclast precursor cell chemotaxis [0.03%]
血小板源性生长因子BB促进破骨细胞形成及前体细胞的趋化作用
Dian-Qi Li,Qi-Long Wan,Janak L Pathak et al.
Dian-Qi Li et al.
Enhanced osteoclast formation increases bone resorption, which triggers bone remodeling. Platelet-derived growth factor BB (PDGF-BB) enhances precursor cell homing, angiogenesis, and bone healing, and thereby could also treat osteoporosis. ...