Banu Guzel Nur,Hakan Nur,Ercan Mihci
Banu Guzel Nur
Mucopolysaccharidosis type III (MPS III) is a neurodegenerative disorder. In MPS III patients, heparan sulfate accumulates in many tissues especially the central nervous system. There are limited data regarding bone involvement in MPS III c...
Decreased rate of hip fracture and consequent reduction in estimated medical costs in Japan [0.03%]
日本髋部骨折发生率下降及相应的医疗费用减少估算
Hiroaki Ohta,Mitsuko Mouri,Tatsuhiko Kuroda et al.
Hiroaki Ohta et al.
The frequency of hip fractures associated with aging of the population is declining in many countries. Even in Japan, where this frequency has been increasing continually, a shift to decreasing frequency has been noted in recent reports. Th...
The effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (HMG-CoA), on the prevention of osteoporosis in ovariectomized rabbits [0.03%]
阿托伐他汀预防卵巢切除兔骨质疏松的实验研究
Huan Zhou,Yunqiu Xie,Zulqarnain Baloch et al.
Huan Zhou et al.
Osteoporosis is a most frequent systemic skeletal disease characterized as low bone mineral density and microarchitectural deterioration of bone tissue, resulting in increased bone fragility and fracture risk. Although several drugs such as...
MiR-142-5p promotes bone repair by maintaining osteoblast activity [0.03%]
MiR-142-5p通过维持成骨细胞活性促进骨骼修复
Manli Tu,Juanjuan Tang,Hongbo He et al.
Manli Tu et al.
MicroRNAs play important roles in regulating bone regeneration and remodeling. However, the pathophysiological roles of microRNAs in bone repair remain unclear. Here we identify a significant upregulation of miR-142-5p correlated with activ...
Wei-Jia Yu,Jin-Wei He,Wen-Zhen Fu et al.
Wei-Jia Yu et al.
Tumor-induced osteomalacia (TIO) is a rare acquired form of hypophosphatemic osteomalacia, which is usually attributed to the overproduction of fibroblast growth factor 23 (FGF-23) by benign mesenchymal neoplasms. Localization and thereafte...
Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies [0.03%]
可用于表观遗传学研究的两个人类成骨细胞系的生成和鉴定
Flor M Pérez-Campo,Tobias May,Jeannette Zauers et al.
Flor M Pérez-Campo et al.
Different model systems using osteoblastic cell lines have been developed to help understand the process of bone formation. Here, we report the establishment of two human osteoblastic cell lines obtained from primary cultures upon transduct...
The association between osteoporotic hip fractures and actinic lesions as a biomarker for cumulative sun exposure in older people-a retrospective case-control study in Argentina [0.03%]
阿根廷老年人骨质疏松性髋部骨折与晒斑关联的病例对照研究
H A Perroud,M S Dagatti,B Amigot et al.
H A Perroud et al.
The aim of this study was to analyze the association between the presence of actinic lesions (solar keratosis and non-melanoma skin cancer) and osteoporotic hip fractures in older patients. Both pathologies are common conditions in this age...
The natural history and hip geometric changes of primary hyperparathyroidism without parathyroid surgery [0.03%]
未经甲状旁腺手术的一发性甲状旁腺功能亢进的自然病史及髋关节几何学变化
Kyong Yeun Jung,A Ram Hong,Dong Hwa Lee et al.
Kyong Yeun Jung et al.
There have been few reports on changes in bone geometry in asymptomatic patients with primary hyperparathyroidism (PHPT) not treated surgically. We reviewed the records concerning biochemical parameters, bone mineral density (BMD), and hip ...
Effects of losartan treatment on the physicochemical properties of diabetic rat bone [0.03%]
洛萨坦对糖尿病大鼠骨物理化学性质的影响
Baris Ozgur Donmez,Mustafa Unal,Semir Ozdemir et al.
Baris Ozgur Donmez et al.
Inhibitors of the renin-angiotensin system used to treat several diseases have also been shown to be effective on bone tissue, suggesting that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may reduce fracture ri...
Challenges to prevent secondary fractures in patients with hip fractures in Joetsu Myoko, Japan through the increased use of osteoporosis treatment and collaboration with family doctors [0.03%]
通过增加骨质疏松症治疗的使用和与家庭医生合作，防止日本上越苗 bo地区髋部骨折患者的二次骨折挑战
Nobuaki Suzuki,Katsumitsu Arai,Saizo Kon et al.
Nobuaki Suzuki et al.
The Niigata Prefectural Central Hospital (NPCH) is one of the main hospitals for the cities of Joetsu and Myoko, Niigata Prefecture, Japan, an area with a population of 240,141, of whom 26.7 % were aged ≥65 years in 2009. In the NPCH, pati...