Vitamin K homologs as potential biomarkers for disease activity in patients with rheumatoid arthritis [0.03%]
维生素K类似物可作为类风湿性关节炎患者疾病活动性的潜在生物标志物
Hani M Khojah,Sameh Ahmed,Mahran S Abdel-Rahman et al.
Hani M Khojah et al.
The aim of this study was to evaluate the possible role of vitamin K homologs as potential biomarkers for disease activity in patients with rheumatoid arthritis (RA). In this study, 42 patients with RA and 40 healthy controls were enrolled....
Lithium chloride enhances bone regeneration and implant osseointegration in osteoporotic conditions [0.03%]
氯化锂能增强骨质疏松条件下的骨再生和种植体骨结合
Yifan Jin,Lihua Xu,Xiaohui Hu et al.
Yifan Jin et al.
Osteoporotic patients have a high risk of dental and orthopedic implant failure. Lithium chloride (LiCl) has been reported to enhance bone formation. However, the role of LiCl in the success rate of dental and orthopedic implants in osteopo...
The safety and effectiveness profile of eldecalcitol in a prospective, post-marketing observational study in Japanese patients with osteoporosis: interim report [0.03%]
依降钙素治疗骨质疏松症的日本患者前瞻性上市后观察性研究的安全性和有效性：中期报告
Hitoshi Saito,Hiroyuki Kakihata,Yosuke Nishida et al.
Hitoshi Saito et al.
This large-scale post-marketing surveillance study was conducted to assess the safety and effectiveness of eldecalcitol treatment in patients with osteoporosis in a Japanese clinical setting. A total of 3567 patients with osteoporosis were ...
Observational Study
Journal of bone and mineral metabolism. 2017 Jul;35(4):456-463. DOI:10.1007/s00774-016-0779-2 2017
Young-Kyun Lee,Jae-Suk Chang,Yong-Ki Min et al.
Young-Kyun Lee et al.
Inadequate calcium and vitamin D intake is a possible risk factor of osteoporosis. Our purposes were to estimate calcium and vitamin D intake in Korean women, and to determine associated risk factors for low calcium and vitamin D intake. Th...
4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress [0.03%]
苯甲酸预防糖皮质激素诱导的骨髓基质细胞向成骨细胞分化过程中的内质网应激和成骨细胞凋亡
Jianhui Yang,Qiong Wu,Jianguo Lv et al.
Jianhui Yang et al.
Apoptosis of osteoblasts triggered by high-dose glucocorticoids (GCs) has been identified as a major cause of osteoporosis. However, the molecular mechanisms underlying GC-induced osteoporosis remain elusive. This study was conducted to mak...
Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral density and body composition in Chinese male nuclear families [0.03%]
METTL21C基因的SNPs和单倍型与中国男性核家庭骨峰值密度及体质成分的关系
Fei Zhao,Li-Hong Gao,Shan-Shan Li et al.
Fei Zhao et al.
The methyltransferase-like 21C gene (METTL21C), which is mainly expressed in muscle, can promote the differentiation of myoblasts to myotubes and reduce glucocorticoid-induced apoptosis of osteocytes. The purpose of this study was to explor...
Platelet-derived growth factor BB enhances osteoclast formation and osteoclast precursor cell chemotaxis [0.03%]
血小板源性生长因子BB促进破骨细胞形成及前体细胞的趋化作用
Dian-Qi Li,Qi-Long Wan,Janak L Pathak et al.
Dian-Qi Li et al.
Enhanced osteoclast formation increases bone resorption, which triggers bone remodeling. Platelet-derived growth factor BB (PDGF-BB) enhances precursor cell homing, angiogenesis, and bone healing, and thereby could also treat osteoporosis. ...
Maternal vitamin D supplementation in pregnancy and offspring outcomes: a double-blind randomized placebo-controlled trial [0.03%]
孕期维生素D补充对子代结局的影响：双盲随机对照试验
Saroj Kumar Sahoo,Kishore Kumar Katam,Vinita Das et al.
Saroj Kumar Sahoo et al.
We studied bone mineral content (BMC), bone mineral density (BMD), and body composition in offspring of women supplemented with vitamin D during pregnancy. Pregnant women were randomized to receive oral cholecalciferol 60,000 units 4 weekly...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2017 Jul;35(4):464-471. DOI:10.1007/s00774-016-0777-4 2017
Genetic admixture and body composition in Puerto Rican adults from the Boston Puerto Rican Osteoporosis Study [0.03%]
波士顿波多黎各人骨质疏松症研究中波多黎各成年人的基因混血及体型构成
Sabrina E Noel,Sandra Arevalo,Caren E Smith et al.
Sabrina E Noel et al.
Population admixture plays a role in the risk of chronic conditions that are related to body composition; however, our understanding of these associations in Puerto Ricans, a population characterized by multiple ancestries, is limited. This...
The influence of the sensory neurotransmitter calcitonin gene-related peptide on bone marrow mesenchymal stem cells from ovariectomized rats [0.03%]
降钙素基因相关肽对卵巢切除大鼠骨髓间充质干细胞的影响
Jie Chen,Ge Ma,Wei Liu et al.
Jie Chen et al.
In order to explore the effects of calcitonin gene-related peptide (CGRP) on bone mesenchymal stem cells (BMSCs) from ovariectomized (OVX) rats, an OVX rat model was used. An ELISA was performed to examine the changes in CGRP level in the p...