Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians [0.03%]
双变量全基因组关联分析在高加索人中识别出骨密度和饮酒的遗传效应
Shan Lu,Lan-Juan Zhao,Xiang-Ding Chen et al.
Shan Lu et al.
Several studies indicated bone mineral density (BMD) and alcohol intake might share common genetic factors. The study aimed to explore potential SNPs/genes related to both phenotypes in US Caucasians at the genome-wide level. A bivariate ge...
Safety, pharmacokinetics, and changes in bone metabolism associated with zoledronic acid treatment in Japanese patients with primary osteoporosis [0.03%]
唑来磷酸治疗原发性骨质疏松症日本患者的疗效、药代动力学及骨代谢变化
Masataka Shiraki,Satoshi Tanaka,Hiroaki Suzuki et al.
Masataka Shiraki et al.
Although once-yearly intravenous administration of zoledronic acid has been reported to inhibit bone resorption and increase bone mineral density, no studies have evaluated its effectiveness in treating osteoporosis in Japanese patients. Th...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2017 Nov;35(6):675-684. DOI:10.1007/s00774-016-0806-3 2017
Use of dual-energy computed tomography to measure skeletal-wide marrow composition and cancellous bone mineral density [0.03%]
双能量CT在测量骨髓组成和松质骨矿物质密度中的应用研究
Luke Arentsen,Karen E Hansen,Masashi Yagi et al.
Luke Arentsen et al.
Temporal and spatial variations in bone marrow adipose tissue (MAT) can be indicative of several pathologies and confound current methods of assessing immediate changes in bone mineral remodeling. We present a novel dual-energy computed tom...
Dietary factors and fibroblast growth factor-23 levels in young adults with African ancestry [0.03%]
饮食因素与非洲血统青年人纤维母细胞生长因子-23水平的关系
Dominique Kosk,Holly Kramer,Amy Luke et al.
Dominique Kosk et al.
Fibroblast growth factor-23 (FGF23), a phosphaturic hormone secreted mainly by osteocytes, maintains serum phosphate levels within a tight range by promoting phosphaturia. Previous studies have mainly focused on the link between FGF23 level...
Nonalcoholic fatty liver disease and osteoporosis: a systematic review and meta-analysis [0.03%]
非酒精性脂肪肝与骨质疏松症：系统评价和荟萃分析
Sikarin Upala,Veeravich Jaruvongvanich,Karn Wijarnpreecha et al.
Sikarin Upala et al.
Several major risk factors for osteoporosis have been identified. One of these risk factors is chronic inflammation. Several recent studies have supported the association between low bone mineral density (BMD) and nonalcoholic fatty liver d...
Bone mineral density of extremities is associated with coronary calcification and biopsy-verified vascular calcification in living-donor renal transplant recipients [0.03%]
骨末端的骨矿密度与活体肾脏移植受者的冠脉钙化和组织学证实的血管钙化相关性研究
Zhimin Chen,Jia Sun,Mathias Haarhaus et al.
Zhimin Chen et al.
Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary arter...
Assessment criteria for vitamin D deficiency/insufficiency in Japan: proposal by an expert panel supported by the Research Program of Intractable Diseases, Ministry of Health, Labour and Welfare, Japan, the Japanese Society for Bone and Mineral Research and the Japan Endocrine Society [Opinion] [0.03%]
日本维生素D缺乏/不足评估标准专家工作组报告：依据厚生劳动省难病研究项目、日本骨与矿物质研究学会及日本内分泌学会制定的意见书
Ryo Okazaki,Keiichi Ozono,Seiji Fukumoto et al.
Ryo Okazaki et al.
Vitamin D is indispensable for the maintenance of bone and mineral health. Inadequate vitamin D action increases the risk for various musculoskeletal/mineral events including fracture, fall, secondary hyperparathyroidism, diminished respons...
Impaired osteogenic differentiation and enhanced cellular receptor of advanced glycation end products sensitivity in patients with type 2 diabetes [0.03%]
2型糖尿病患者的成骨分化受损和细胞受体AGEs敏感性增强
Mattabhorn Phimphilai,Peraphan Pothacharoen,Prachya Kongtawelert et al.
Mattabhorn Phimphilai et al.
Preclinical studies have demonstrated impaired osteoblast differentiation in type 2 diabetes (T2DM), which is related to skeletal accumulation of advanced glycation end products (AGEs). However, the role of AGE in osteoblast differentiation...
The association of testosterone, sex hormone-binding globulin, and insulin-like growth factor-1 with bone parameters in Korean men aged 50 years or older [0.03%]
韩国50岁以上男性睾酮、性激素结合球蛋白和胰岛素样生长因子-1与骨参数相关性的横断面研究
Hye-Jung Kim,Hyung Suk Koo,Young-Sang Kim et al.
Hye-Jung Kim et al.
Testosterone and insulin-like growth factor-1 (IGF-1) are essential factors for the maintenance of bone health in men. However, the results for the association of testosterone and IGF-1 with bone parameters were not consistent in prior stud...
Increased risk of hip fractures in Korean patients with type 2 diabetes: a 6-year nationwide population-based study [0.03%]
韩国2型糖尿病患者髋部骨折风险增加：一项为期六年的基于全国人口的调查研究
Se Hwa Kim,Yoo Mee Kim,Jeong Seon Yoo et al.
Se Hwa Kim et al.
We compared the incidence and risk of hip fractures in Korean patients with type 2 diabetes and non-diabetic subjects in a nationwide population-based study. The study included 17,110 patients diagnosed with type 2 diabetes in 2004 and 34,2...