Trolox, r-irisin and resveratrol cocktail to counteract osteoblast metabolism alterations in osteoarthritis and osteoporosis [0.03%]
用于对抗骨关节炎和骨质疏松症中成骨细胞代谢变化的托洛克斯、r-鸢燕醇和白藜芦醇鸡尾酒疗法
Roberto Bonanni,Angela Falvino,Amarildo Smakaj et al.
Roberto Bonanni et al.
Introduction: Osteoarthritis and osteoporosis are age-related musculoskeletal disorders characterized by increased oxidative stress and cellular senescence, which contribute to altered metabolism and disease progression. ...
Response to the Letter to the Editor: "Rheumatoid arthritis and subsequent fracture risk" [0.03%]
关于编辑部来信“类风湿性关节炎与骨折风险”的回应
Takefumi Furuya,Eisuke Inoue,Hisashi Yamanaka et al.
Takefumi Furuya et al.
Randomized crossover comparison of two teriparatide self-injection regimens for primary osteoporosis: final report of the Japanese Osteoporosis Intervention Trial 06 (JOINT-06) [0.03%]
特立帕肽两种自注射方案治疗绝经后骨质疏松症的交叉过床研究：日本骨质疏松症干预性临床试验（JOINT）最终报告
Sakae Tanaka,Yukari Uemura,Shiro Tanaka et al.
Sakae Tanaka et al.
Introduction: Although bone anabolic agents such as teriparatide are effective for osteoporosis, satisfaction and adherence may vary by regimen. This multicenter study assessed long-term satisfaction, persistence, efficac...
In memory of Dr. Hajime Orimo : January 11, 1935, to May 16, 2025 [0.03%]
悼念大熊早水博士：1935年1月11日至2025年5月16日
Sumito Ogawa
Sumito Ogawa
Osmotic stress inhibits osteoblast differentiation and mineralization by suppressing TRPV4-mediated calcium influx [0.03%]
渗透胁迫通过抑制TRPV4介导的钙离子内流来抑制成骨细胞分化和矿化作用
Takashi Miyano,Haruka Hasegawa,Toshihiro Sera
Takashi Miyano
Introduction: Hyperglycemia increases the risk of bone fragility by promoting reactive oxygen species and advanced glycation end products, which disrupt osteoblast activity. Mechanical stress, including osmotic stress fro...
Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity [0.03%]
不健康的生活方式加速衰老并导致骨骼肌肉系统疾病患病率上升
Hao-Long Zhou,Jiao-Jun Liang,Jonathan K L Mak et al.
Hao-Long Zhou et al.
Introduction: Few studies assessed comprehensive effects of composite unhealthy lifestyles on aging and musculoskeletal health. This study aimed to address such issues with the UK Biobank datasets. ...
Time-dependent improvement of quality of life with teriparatide or alendronate therapy: a JOINT-05 sub-analysis [0.03%]
甲状旁腺素和阿仑膦酸钠治疗对生命质量影响的时程变化——JOINT-05研究的事后分析
Satoshi Mori,Shiro Tanaka,Tatsuhiko Kuroda et al.
Satoshi Mori et al.
Introduction: The effects of teriparatide (TPTD) and alendronate (ALN) on health-related quality of life (HRQOL) were evaluated in osteoporotic patients with high fracture risk using data from the JOINT-05 trial. ...
Author's response to letter to the editor: Re: Randomized crossover comparison of two teriparatide self-injection regimens for primary osteoporosis: interim report of JOINT-06 [0.03%]
终稿回应信：随机交叉对比特立帕肽两种自注射方案治疗原发性骨质疏松症的JOINT-06研究中期结果
Satoshi Soen,Yukari Uemura,Shiro Tanaka et al.
Satoshi Soen et al.
Response to the letter regarding "Increased complications of proximal femur fractures during the COVID-19 pandemic" [0.03%]
关于“新冠大流行期间股骨近端骨折并发症增加”的来信回复
Hidetatsu Tanaka,Kunio Tarasawa,Yu Mori et al.
Hidetatsu Tanaka et al.
Independent risk factors and survival prediction in hip refractures patients: insights from a 10-year cohort [0.03%]
独立危险因素和髋部骨折患者的生存预测：一项为期十年的队列研究的见解
Ruilong Qi,Guohong Xu,Zhengtong Lin et al.
Ruilong Qi et al.
Introduction: Hip fracture (HF) is one of the leading causes of mortality and disability in older populations. Hip refracture (HRF) is more serious than HF. We examined the survival rates of patients with HRFs at the Affi...