Vitamin D-mediated hypercalcemia in multicentric Castleman's disease [0.03%]
多中心Castleman病的维生素D介导的高钙血症
Ken-Ichiro Tanaka,Ippei Kanazawa,Hitomi Miyake et al.
Ken-Ichiro Tanaka et al.
Multicentric Castleman's disease (MCD) is a rare lymphoproliferative disorder, which represents various symptoms caused by the hyperproduction of interleukin-6 (IL-6). However, case studies of MCD accompanied by hypercalcemia have rarely be...
Expected lifetime numbers, risks, and burden of osteoporotic fractures for 50-year old Chinese women: a discrete event simulation incorporating FRAX [0.03%]
基于FRAX的中国女性50岁人群一生中发生骨质疏松性骨折的风险及疾病负担的预测：离散事件模拟研究
Yawen Jiang,Weiyi Ni
Yawen Jiang
This work was undertaken to provide an estimation of expected lifetime numbers, risks, and burden of fractures for 50-year-old Chinese women. A discrete event simulation model was developed to simulate the lifetime fractures of 50-year-old ...
Relationships between the lean mass index and bone mass and reference values of muscular status in healthy Chinese children and adolescents [0.03%]
中国健康儿童和青少年体脂指数与骨量的关系及肌肉状况的参考值
Bin Guo,Qiulian Wu,Jian Gong et al.
Bin Guo et al.
This study aimed to analyze the relationships between the lean mass index (LMI) and bone outcomes in Chinese children and adolescents using dual-energy X-ray absorptiometry (DXA) and to establish sex-specific reference percentile curves for...
Alkaline phosphatase determines polyphosphate-induced mineralization in a cell-type independent manner [0.03%]
无细胞类型的碱性磷酸酶决定多聚磷酸诱导的矿化作用
Yoshikazu Mikami,Hiromasa Tsuda,Yuko Akiyama et al.
Yoshikazu Mikami et al.
Polyphosphate [Poly(P)] has positive effects on osteoblast mineralization; however, the underlying mechanism remains unclear. In addition, it is unknown whether Poly(P) promotes mineralization in soft tissues. We investigated this by using ...
Alendronate does not prevent long bone fragility in an inactive rat model [0.03%]
阿仑膦酸不能预防活动减少大鼠长骨脆性增加
K Naruse,K Uchida,M Suto et al.
K Naruse et al.
The lack of estrogen and inactivity are both important in the pathogenesis of osteoporosis in elderly women, and there have been no appropriate rodent studies to examine the effects of common bisphosphonates on these two components separate...
Higher response with bone mineral density increase with monthly injectable ibandronate 1 mg compared with oral risedronate in the MOVER study [0.03%]
一项比较每月注射依班膦酸钠与口服利塞磷酸盐对骨密度影响的临床研究（MOVER研究）
Tetsuo Nakano,Masao Yamamoto,Junko Hashimoto et al.
Tetsuo Nakano et al.
We examined response to bone mineral density (BMD) gains in the MOVER study following treatment with intravenous (IV) ibandronate 1 mg/month, and investigated the characteristics of a non-responder group. At 1 year, responder rates for pati...
Randomized Controlled Trial
Journal of bone and mineral metabolism. 2016 Nov;34(6):678-684. DOI:10.1007/s00774-015-0717-8 2016
Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males [0.03%]
基于924例日本男性尸体解剖的股骨骨折终生患病率的遗传风险评分
Heying Zhou,Seijiro Mori,Tatsuro Ishizaki et al.
Heying Zhou et al.
A genetic risk score (GRS) was developed for predicting fracture risk based on lifetime prevalence of femoral fractures in 924 consecutive autopsies of Japanese males. A total of 922 non-synonymous single nucleotide polymorphisms (SNPs) loc...
Z-score discordance and contributing factors in healthy premenopausal women with low bone mineral density: the Korean National Health and Nutrition Examination Survey 2008-9 [0.03%]
韩国2008至2009年国民健康与营养调查中的低骨密度健康育龄妇女的Z评分差异及其影响因素
Kyeong Hye Park,Jung Soo Lim,Kyoung Min Kim et al.
Kyeong Hye Park et al.
The premenopausal period is important for bone health and prevention of future fractures, but measuring bone mineral density (BMD) at only one site may not be sufficient to determine therapeutic strategies for low BMD in premenopausal women...
The role of serum osteoprotegerin and receptor-activator of nuclear factor-κB ligand in metabolic bone disease of women after obesity surgery [0.03%]
肥胖手术后女性代谢性骨病患者血清osteoprotegerin和核因子κB受体活化剂配基的作用
José A Balsa,Christian Lafuente,Jesús M Gómez-Martín et al.
José A Balsa et al.
Metabolic bone disease may appear as a complication of obesity surgery. Because an imbalance in the osteoprotegerin and receptor-activator of nuclear factor-κB ligand system may underlie osteoporosis, we aimed to study this system in human...
Identification and functional analysis of a novel CaSR mutation in a family with familial hypocalciuric hypercalcemia [0.03%]
家族性低钙尿高钙血症家系中新型CaSR突变的鉴定及功能分析
Eun Sook Kim,Su Yeon Kim,Ji Young Lee et al.
Eun Sook Kim et al.
The calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that plays an essential role in maintaining calcium homeostasis. In the present study, we analyzed the CaSR gene in a Korean family with familial hypocalciuric hypercalcemi...