Preparation and Application of an Antibody Specifically Targeting Tyrosine-Phosphorylated PI3K p85 at Position 452 [0.03%]
特异性靶向452位酪氨酸磷酸化PI3K p85抗体的制备及应用
Dongliang Zhang,Shulong Wang,Yinxiu Chi
Dongliang Zhang
Background: The current invention pertains to the development and utilization of an antibody that specifically recognizes tyrosine-phosphorylated PI3K p85 at position 452. The process encompasses antigen preparation, immu...
A Predictive Framework for Acute Liver Failure Outcomes: Insights from Nonbiological Artificial Liver Treatment [0.03%]
急性肝衰竭预后预测框架的构建及人工肝脏治疗的临床获益研究
Shuang Sun,Shu-Xian Wang,De-Shu Dai et al.
Shuang Sun et al.
Background: The aim of this study was to evaluate the efficacy of nonbiological artificial liver (NBAL) in the treatment of acute liver failure (ALF) and to screen prognostic predictors. ...
Observational Study
Clinical laboratory. 2026 Jul 1;72(7). DOI:10.7754/Clin.Lab.2025.250801 2026
Toxicological Effects of Benzene on Blood and Biochemical Profiles Among Fuel Station Workers in Southern Saudi Arabia [0.03%]
沙特南方加油站工作人员的苯毒性对血液和生化指标的影响
Ayed A Dera,Mesfer Al Shahrani,Khaled Gawa et al.
Ayed A Dera et al.
Background: Benzene is a widely-used industrial solvent recognized for its toxic effects on multiple organ systems. Occupational exposure, particularly among gasoline station attendants, has been associated with hematolog...
Epidemiological and Biological Profiles of Constitutional Coagulation Deficiencies at CHU Ibn Rochd Hematology Laboratory [0.03%]
慢性凝血功能障碍的流行病学及生物学特征——CHU Ibn Rochd血液科实验室研究
H Tourbih,A Harrach,H Bencharef et al.
H Tourbih et al.
Background: Rare coagulation factor deficiencies are uncommon inherited bleeding disorders that remain poorly understood in many parts of the world, including Morocco. They primarily involve factors I, II, V, VII, X, XI, ...
Identification of Biomarkers and Construction of Predictive Models for Sepsis and Septic Shock [0.03%]
脓毒症和脓毒性休克生物标志物的识别及预测模型构建
Fan Yu,Shuang Lou,Wei Wei et al.
Fan Yu et al.
Background: Sepsis is a serious condition resulting from an uncontrolled immune response to infection, often leading to organ dysfunction and septic shock. Current biomarkers have limitations in reflecting disease severit...
Associations between Immune Cell Traits and Tonsil and Adenoid Hypertrophy in Children: a Bidirectional Two-Sample Mendelian Randomization Study [0.03%]
免疫细胞特征与儿童扁桃体和腺样体肥大的关联：双向两样本孟德尔随机化研究
Xiaoyu Wen,Jiarou Zhong,Yunyun Luo et al.
Xiaoyu Wen et al.
Background: Mounting evidence indicates associations between immune cells and chronic diseases of the tonsils and adenoids (CDTA). Whether these observational links reflect underlying causality has yet to be determined. T...
The Application of Machine Learning in the Formation Mechanism of Eosinophilic Pleural Effusion [0.03%]
机器学习在嗜酸性胸腔积液发病机制中的应用研究
Xu Yuan,Ming Huang,Hui Zhang et al.
Xu Yuan et al.
Background: The aim of this study was to establish a critical point model for the transudation of eosinophils through the pleura using machine learning techniques. This model treats the presence or absence of eosinophils ...
Retrospective Review of Specimen Rejections in 2024: Insights from a Regional Hospital Laboratory [0.03%]
2024年标本拒收回顾性分析：某地区医院实验室的见解
Yun-Jin Yang,Yi-Lin Yang,Tze-Kiong Er
Yun-Jin Yang
Background: Specimen rejection is a critical quality indicator in clinical laboratories, often resulting from pre-analytical errors that compromise diagnostic accuracy and patient care. This retrospective study analyzed r...
METTL3-Driven Maturation of miR-103 Promotes the Progression of Non-Small Cell Lung Cancer [0.03%]
METTL3介导的miR-103成熟促进非小细胞肺癌进展
Yi Luo,Yang Liu,Junwei Ma et al.
Yi Luo et al.
Background: This study aimed to elucidate the molecular mechanism underlying the m6A modification of miR-103 and its role in promoting proliferation and epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI...
Saliva-Based Triple-Primed PCR as a Non-Invasive Tool for Detecting NOTCH2NLC GGC Repeat Expansions in NIID [0.03%]
基于唾液的三重引物PCR技术作为非侵入性检测NIID中NOTCH2NLC GGC重复扩增的工具
Yangye Lian,Shaoping Zhong,Jingzhen Liang et al.
Yangye Lian et al.
Background: NOTCH2NLC-related neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by abnormal expansions of GGC repeats in the NOTCH2NLC gene. Traditional genetic testing relies on blood ...