Localized bone deterioration predicts declining failure load and increased fracture risk [0.03%]
局部骨质量恶化预示着承力下降和骨折风险增加
Annabel R Bugbird,Lauren A Burt,Danielle E Whittier et al.
Annabel R Bugbird et al.
Localized bone loss, known as void spaces, has not been previously assessed longitudinally. This study investigated age- and sex-related changes in void spaces over time and explored their relationship with fracture risk and bone strength. ...
Beyond the initial impact: a systematic review of post-traumatic bone loss and its mechanisms [0.03%]
初始影响之外：创伤后骨丢失及其机制的系统评价
Adibeh Rahmani,Ulrike Weichelt,Denise Jahn et al.
Adibeh Rahmani et al.
Post-traumatic bone loss occurs after major injuries like traumatic brain injury (TBI), spinal cord injury (SCI), burns, and fractures, yet its systemic effects remain underexplored. This review summarizes clinical and preclinical evidence,...
Explainable opportunistic osteoporosis screening from chest X-rays: a retrospective comparison of foundation models [0.03%]
基于胸部X光片的可解释机会性骨质疏松筛查：基础模型的回顾性比较研究
Jaewon Kim,Sangmin Kwak,Hyeokjong Lee et al.
Jaewon Kim et al.
We evaluated foundation models for opportunistic osteoporosis screening from chest X-rays using a novel explainability framework. DINOv2 with low-rank adaptation achieved the best performance (AUC 0.93) while demonstrating clear clinical re...
Clarifying the interpretation of metapgs and cumulative incidence in fracture risk prediction [0.03%]
阐明骨折风险预测中metapgs和累积发病率的解释
Marjan Hosseinpour
Marjan Hosseinpour
Author's response to letter to editor "Comment on: Effectiveness of treatment initiation for secondary fracture prevention in the older population: Japanese Bone-fracture Osteoporosis in Late-stage population Database study (J-BOLD)-emulation of a randomized target trial" (OSIN-D-25-01923) [0.03%]
作者对“关于：老年人二次骨折预防治疗启动效果的日本骨折骨质疏松晚期人口数据库研究(J-BOLD)——随机对照试验仿真”信件的回复(OSIN-D-25-01923)
Manabu Tsukamoto,Takahiko Hamasaki,Nobukazu Okimoto et al.
Manabu Tsukamoto et al.
Follow-on osteoporosis therapy after denosumab discontinuation among Medicare beneficiaries [0.03%]
医疗保险受益人在停用地诺单抗后的骨质疏松治疗状况
Selvam R Sendhil,Suzanne M Cadarette,Sulbh Aggarwal et al.
Selvam R Sendhil et al.
Denosumab is an effective osteoporosis therapy, but discontinuing treatment can result in rebound-associated fractures. Guidelines recommend starting follow-on osteoporosis therapy within 6 months of the last dose, but real-world practice i...
Ankle fractures: a pragmatic opportunity for osteoporosis case finding [0.03%]
踝关节骨折：诊断骨质疏松症的 pragmatics 机会
Chao-Chun Huang
Chao-Chun Huang
The association of bone density and hip fracture risk among Asian women [0.03%]
亚洲女性骨密度与髋部骨折风险的相关性研究
Joan C Lo,Malini Chandra,Wei Yang et al.
Joan C Lo et al.
Asian women have lower bone density than White women, but their hip fracture risk similarly increased two-fold or more for each unit decline in bone density T-score. Adjusting for age, T-score, and treatment, hip fracture risk remained lowe...
Misstated prevalence in fragility-fracture consensus: need for peer-reviewed national data [0.03%]
脆性骨折共识中的误报患病率问题：亟需经过同行评议的国家数据
Audai Abudayeh,Iakiv Fishchenko
Audai Abudayeh