Functional Status Trends for Adults and Children on Extracorporeal Membrane Oxygenation at Time of Lung Transplantation [0.03%]
体外膜氧合支气管肺移植患者的预后分析
Wonshill Koh,JangDong Seo,Nicholas J Ollberding et al.
Wonshill Koh et al.
Poor or worsening functional status of lung transplant (LTx) candidates is a key risk factor for waitlist and post-transplant mortality. As more critically ill adults and children are listed for LTx, the use of extracorporeal membrane oxyge...
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far? [0.03%]
果糖-2,6-二磷酸酶在肺部疾病中的作用：我们目前了解多少？
Diandian Li,Lian Liu,Jiangyue Qin et al.
Diandian Li et al.
Pyruvate kinase M2 (PKM2) is a critical enzyme regulating cell metabolism and growth under different physiological conditions. In its metabolic role, PKM2 catalyzes the final and also a rate-limiting reaction in the glycolytic pathway, conv...
Impact of Asthma and Obstructive Sleep Apnea on Central Airways Resistance During Pregnancy [0.03%]
哮喘和阻塞性睡眠呼吸暂停对孕妇中央气道阻力的影响
Christopher Theroux,Christina Raker,Melissa Guillen et al.
Christopher Theroux et al.
Purpose: Pregnancy is a risk factor for the development of obstructive sleep apnea (OSA) and for worsening of asthma; the interaction between the two disorders is not well described. We aimed to examine airway mechanics i...
Yan Lin,Jiaqi Chen,Jiale Tan et al.
Yan Lin et al.
Pericytes, specialized mural cells residing within the basement membrane of pulmonary microvessels, participate in various biological processes, including vascular homeostasis, immunomodulation, and tissue repair. However, these beneficial ...
Jeffrey D Ritzenthaler,Edilson Torres-Gonzalez,Yvonne Janssen-Heininger et al.
Jeffrey D Ritzenthaler et al.
Oxidative stress has been implicated in lung injury and repair. We seek to understand how alterations in the plasma redox potential (Eh) of the thiol disulfide couple cysteine (Cys) and cystine (CySS) (Eh Cys/CySS) affect this process. Prev...
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials [0.03%]
影响慢性阻塞性肺疾病单克隆抗体生物药疗效和安全性的因素：随机对照试验的 meta 分析
Yuxin Wang,Jinmei Luo,Rong Huang et al.
Yuxin Wang et al.
Background: Monoclonal antibody therapies targeting specific inflammatory pathways have shown potential in treating chronic obstructive pulmonary disease (COPD). However, the efficacy and safety of these treatments across...
Efficacy and Safety of Superior Laryngeal Nerve Block in the Management of Neuropathic Cough: A Systematic Review [0.03%]
喉上神经阻滞治疗神经性咳嗽的有效性和安全性系统评价
Andrea Campagnolo,Vinícius Nickel,Michael S Benninger
Andrea Campagnolo
Objectives: To systematically review the efficacy and safety, both short and long-term, of superior laryngeal nerve block (SLNB) for managing neuropathic cough. ...
Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment [0.03%]
慢性咳嗽中的卡塔和缪类阿片受体：现有证据及未来治疗方向
Surinder S Birring,Peter V Dicpinigaitis,Toby M Maher et al.
Surinder S Birring et al.
Chronic cough is a significant burden on patient quality of life and is associated with poor health outcomes. Chronic cough may be a result of neural hypersensitivity due to changes in both the peripheral and the central nervous systems, al...
Efficacy and Safety of Fexuprazan Versus Esomeprazole for Gastroesophageal Reflux Disease-Related Chronic Cough: A Randomized, Double-Blind, Active-Controlled Exploratory Trial [0.03%]
富马酸非洛扎胺治疗胃食管反流病相关性慢性咳嗽的疗效和安全性：一项随机、双盲、阳性药对照性的探索性试验
Noeul Kang,Min-Gyu Kang,Seung Eun Lee et al.
Noeul Kang et al.
Purpose: Potassium-competitive acid blockers (P-CABs) are a newer class of acid suppressants with convenient dosing and a rapid onset of action, while showing efficacy comparable to proton pump inhibitors (PPIs) in treati...
Randomized Controlled Trial
Lung. 2025 Apr 29;203(1):59. DOI:10.1007/s00408-025-00815-5 2025
Genome-Wide Differential Airway Gene Expression Analysis Identifies Genes Associated with COPD Comorbidities [0.03%]
全基因组差异气道基因表达分析确定与COPD合并症相关的基因
Alen Faiz,Else A M D Ter Haar,Jorine E Hartman et al.
Alen Faiz et al.
Chronic obstructive pulmonary disease (COPD) is often associated with the co-occurrence of extra-pulmonary diseases, yet the underlying pathophysiology of comorbidities is poorly understood. In COPD patients, the bronchial epithelium often ...