Modified Tracheobronchoplasty for Chronic Cough Due to Excessive Dynamic Airway Collapse: A Case Series [0.03%]
改良气管支气管成形术治疗重度动态气道塌陷慢性咳嗽(病例系列)
Alessandro Gonfiotti,Alessandra Sorano,Massimo O Jaus et al.
Alessandro Gonfiotti et al.
Serum Cytokeratin 18 and Fragment as Biomarkers for Severity and Prognosis in Acute Exacerbation of Chronic Obstructive Pulmonary Disease [0.03%]
细胞角蛋白18及其片段在慢性阻塞性肺疾病急性加重期中的生物标志价值研究
Ming-Yan Liu,Kai-Xin Qu,Kai-Shu Ma et al.
Ming-Yan Liu et al.
Background: Cytokeratin (CK)18 is present in the bronchi and alveolar epithelium of the lung, and its cleavage product, CK-18M30, serves as a biological marker of apoptosis. However, the specific roles of CK-18 and CK-18M...
Unnerving Cough in CANVAS: Cough Hypersensitivity Despite Airway Nerve Depletion [0.03%]
CANVAS研究中的令人不安的咳嗽：气道神经耗竭下的咳嗽高敏状态
Barnaby Hirons,Katherine Rhatigan,William McNulty et al.
Barnaby Hirons et al.
Introduction: Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a genetic neurodegenerative condition associated with chronic cough and cough hypersensitivity. The neuropathic mechanisms unde...
Case Reports
Lung. 2025 Aug 8;203(1):86. DOI:10.1007/s00408-025-00838-y 2025
Stratifying GAP Stages by MUC5B rs35705950 T-Allele Carriage Refines Survival Prediction in IPF [0.03%]
MUC5B rs35705950 T等位基因携带情况可将GAP分期进一步分层以优化IPF患者的生存预测
Joanne J van der Vis,Antje Prasse,Elisabetta A Renzoni et al.
Joanne J van der Vis et al.
The genetic contribution to idiopathic pulmonary fibrosis (IPF) has become increasingly evident, enabling its translation into clinical practice. MUC5B rs35705950 has emerged as a promising prognostic biomarker. The gender-age-physiology (G...
Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma [0.03%]
肺组织顺应性与平滑肌相互作用并驱动实验性哮喘小鼠的高反应性
Sébastien Hecht,Andrés Rojas-Ruiz,Magali Boucher et al.
Sébastien Hecht et al.
Introduction: A recent study on BALB/c and C57BL/6 mice demonstrated a clear lack of association between the in vivo response to nebulized methacholine and the degree of airway narrowing ex vivo in a model of asthma induc...
Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study [0.03%]
慢性咳嗽患者气道黏液栓的观察研究
Kyongmin Sarah Beck,Dae Hee Han,Hyun-Seob Jeon et al.
Kyongmin Sarah Beck et al.
Background: This study investigated the prevalence of mucus plugs and their clinical associations in patients with chronic cough. Methods: ...
Observational Study
Lung. 2025 Jul 24;203(1):83. DOI:10.1007/s00408-025-00839-x 2025
Evidence that Mast Cells Regulate the Cough Hypersensitivity Associated with Eosinophilic Bronchitis [0.03%]
嗜酸细胞性支气管炎相关咳嗽敏感性增加与肥大细胞调控有关的证据
Li Yu,Qi Liu,Brendan J Canning
Li Yu
Purpose: Eosinophils have been implicated as key effectors in the emergence of chronic cough. But causality has not been firmly established, and many patients with cough secondary to eosinophilic bronchitis (EB) are likel...
ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry [0.03%]
韩国慢性咳嗽登记处的难治性慢性咳嗽的ICD-10诊断编码模式及临床相关因素分析
Min-Hye Shin,Young-Jae Lee,Kyung Eun Park et al.
Min-Hye Shin et al.
The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lacks a specific code for refractory chronic cough (RCC). This study analyzed ICD-10 coding patterns among 331 RCC patien...
From Glucotoxicity to Lung Injury: Emerging Perspectives on Diabetes-Associated Respiratory Complications [0.03%]
从高血糖毒性到肺损伤：糖尿病相关呼吸并发症的新视角
Hongmei Yu,Jie Liu,Xiaojuan He
Hongmei Yu
Emerging evidence highlights glucose toxicity as a pivotal driver of diabetic respiratory complications, characterized by hyperglycemia-induced metabolic dysregulation and multi-organ damage. The lung, a metabolically active organ, exhibits...
Soluble Transferrin Receptor-1 in Pulmonary Hypertension Associated with COPD [0.03%]
慢性阻塞性肺疾病相关性肺动脉高压患者可溶转铁蛋白受体-1水平测定
Oleh Myronenko,Pero Curcic,Philipp Douschan et al.
Oleh Myronenko et al.
Purpose: The pulmonary vascular involvement of COPD ranges from severe airway obstruction without pulmonary hypertension (PH) to mild airway obstruction with severe PH. Iron-dependent molecular regulators like hypoxia-ind...