Asthma Reporting with Anti-TNFα Drugs used in Inflammatory Joint Diseases: A Vigibase® Study with Disproportionality Analysis [0.03%]
抗肿瘤坏死因子α药物治疗炎症性关节病患者的哮喘报告：一项关于数据库的 disproportionality 分析研究
Matthias Nocenti,François Montastruc,Yannick Degboe et al.
Matthias Nocenti et al.
Large studies investigating asthma as a potential adverse event of anti-TNFα drugs are lacking. In our study, asthma was more likely to be reported with anti-TNFα drugs compared to biologics and small molecules in RA but exclusively with ...
Admission Serum KL-6 Predicts Mechanical Ventilation Requirement and Mortality in Hospitalized Interstitial Lung Disease Patients: A Single-Center Prospective Study [0.03%]
入院血清KL-6可预测住院间质性肺病患者的机械通气需求和死亡率：一项单中心前瞻性研究
Xing He,Shijie Zhang,Jiao Wang et al.
Xing He et al.
Background: Hospitalized patients with interstitial lung disease (ILD) are at high risk of requiring mechanical ventilation (MV), which is associated with substantial mortality. This study investigated the predictive valu...
Observational Study
Lung. 2026 Mar 27;204(1):18. DOI:10.1007/s00408-026-00882-2 2026
The Effect of the Novel Macrolide Glasmacinal (EP395) on Allergen-Induced Eosinophil Infiltration into the Lung [0.03%]
新型大环内酯抗生素Glasmacinal对吸入变应原所致肺组织嗜酸性粒细胞浸润的影响研究
Jennifer A Kricker,Yanira Riffo-Vasquez,Virginia Norris et al.
Jennifer A Kricker et al.
Purpose: Patients with frequent exacerbations of COPD despite bronchodilator therapy may benefit from inhaled corticosteroids (ICS) if they have eosinophilic inflammation. For those who exacerbate despite bronchodilators ...
Elevated Driving Pressure in Pressure-Controlled Ventilation: An Independent Risk Factor for Adverse Outcomes in Mechanically Ventilated Neonates [0.03%]
压力控制通气中的过高驱动压是机械通气新生儿不良结局的独立风险因素
ShaoCong Zheng,Ya Sun,YuanYi Dai et al.
ShaoCong Zheng et al.
Background: Driving pressure (DP) has recently gained attention as a meaningful variable in lung-protective ventilation, particularly in studies of adult acute respiratory distress syndrome. Its role in neonates, particul...
Long-Term Prognosis of Adult Patients with Persistent Cough Post COVID-19 and Its Risk Factors: A Nationwide Prospective Study [0.03%]
新冠后成人持续咳嗽的长期预后及其危险因素：一项全国前瞻性研究
Wen He,Jianyong Zhang,Dejun Sun et al.
Wen He et al.
Background: There are few data regarding the duration, long-term prognosis of persistent cough post coronavirus disease 2019 (COVID-19). The break of COVID-19 Omicron mutant infection provides an opportunity to investigat...
Multicenter Study
Lung. 2026 Mar 18;204(1):15. DOI:10.1007/s00408-026-00879-x 2026
Róisín Cullen,Kirtana Jagadeesh Nayak,Dave Singh et al.
Róisín Cullen et al.
Background: Malnutrition is often overlooked as an extrapulmonary comorbidity in chronic obstructive pulmonary disease (COPD) and there is limited information regarding the nutritional status of younger individuals with m...
Lung Volumes in Tobacco-Exposed Individuals with Preserved Spirometry: An Overlooked Pointer of Respiratory Health? [0.03%]
吸烟者肺功能保存良好的个体的肺容量：被忽视的呼吸健康指标吗？
Charmaine J M Lim,Emiel F M Wouters,Tobias L Mraz et al.
Charmaine J M Lim et al.
Purpose: Spirometry, the standard for diagnosing chronic obstructive pulmonary disease, has limited sensitivity for early identification of tobacco-exposed individuals with preserved spirometry (TEPS) at risk for respirat...
Longitudinal Multimodal Assessment of Pulmonary Nodules in Fibrosing Interstitial Lung Diseases: A Retrospective Study [0.03%]
纤维化间质性肺疾病的肺结节的纵向多模态评估：回顾性研究
Tommaso Pianigiani,Paolo Cameli,Michele Di Lorenzo et al.
Tommaso Pianigiani et al.
Background: Pulmonary nodules are increasingly detected during high-resolution computed tomography (HRCT) surveillance in patients with fibrosing interstitial lung diseases (fILD). However, nodule risk stratification is c...
Observational Study
Lung. 2026 Mar 9;204(1):11. DOI:10.1007/s00408-026-00877-z 2026
Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness and Mucus Hypersecretion [0.03%]
抗氧化剂、N-乙酰半胱氨酸及艾拉明肽（SS-31）对臭氧所致气道高反应性和黏液高分泌的作用机制研究
Meiqin Xie,Jiali Weng,Chenfei Li et al.
Meiqin Xie et al.
Background: Ozone (O₃) exposure induces acute airway injury characterized by airway hyperresponsiveness (AHR) and airway mucus hypersecretion (AMH). Oxidative stress and mitochondria-derived reactive oxygen species (mtRO...
Clinical History, Spirometry, and CT Features Can Predict Dyspnea in Smokers with and without Spirometry-Defined COPD [0.03%]
临床病史、肺功能和CT特征可预测有无明确肺功能定义的COPD吸烟患者的呼吸困难症状
Joosun Shin,Mary E Cooley,Marilyn J Hammer et al.
Joosun Shin et al.
Rationale: Dyspnea is common in smokers with or without chronic obstructive pulmonary disease. Its multifactorial nature makes it challenging to identify specific factors causing dyspnea in smokers with and without chroni...