Identification of ZNF331 as a Biomarker for Obstructive Sleep Apnea in Idiopathic Pulmonary Fibrosis Through Integrated Bioinformatics Analysis and Clinical Validation [0.03%]
通过整合生物信息学分析和临床验证鉴定ZNF331作为特发性肺纤维化患者阻塞性睡眠呼吸暂停的生物标志物
Shuo Wang,Yanwen Zhang,Jihong Feng et al.
Shuo Wang et al.
Background: Obstructive sleep apnea (OSA) is highly prevalent in patients with idiopathic pulmonary fibrosis (IPF), yet symptom-based screening frequently lacks reliability in this population. We aimed to identify a blood...
Identification of ZNF331 as a Biomarker for Obstructive Sleep Apnea in Idiopathic Pulmonary Fibrosis Through Integrated Bioinformatics Analysis and Clinical Validation [0.03%]
通过综合生物信息学分析和临床验证将ZNF331鉴定为特发性肺纤维化阻塞性睡眠呼吸暂停的生物标志物
Shuo Wang,Yanwen Zhang,Jihong Feng et al.
Shuo Wang et al.
Background: Obstructive sleep apnea (OSA) is highly prevalent in patients with idiopathic pulmonary fibrosis (IPF), yet symptom-based screening frequently lacks reliability in this population. We aimed to identify a blood...
Comparison Between EGFR-TKI Efficacy in Early-Stage Non-small Cell Lung Cancer and Advanced Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis [0.03%]
表早期非小细胞肺癌与晚期非小细胞肺癌患者EGFR-TKI疗效的系统评价和meta分析
Bingxue Wang,Yang Yao,Zhangxuan Chen et al.
Bingxue Wang et al.
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are the standard of care for advanced non-small cell lung cancer (NSCLC). However, their comparative efficacy and safety profile in early...
Mario Cazzola,Daiana Stolz,Don D Sin et al.
Mario Cazzola et al.
The U.S. Food and Drug Administration's proposal to adopt a single randomized controlled trial (RCT) as the default evidentiary standard for drug approval marks a substantial change in regulatory philosophy. Although advances in mechanistic...
One Trial to Rule them all, One Trial to Bind them: But will it Work for COPD? [0.03%]
一场试验来主导他们,一场试验来束缚他们——但对慢性阻塞性肺疾病有效吗?
Peter Calverley
Peter Calverley
Editorial
Lung. 2026 Jul 31;204(1):53. DOI:10.1007/s00408-026-00919-6 2026
Impact of Epigenetic Modifications in Airway Diseases. Role of Inflammation, Environmental Factors and Aging [0.03%]
表观遗传修饰在气道疾病中的影响:炎症、环境因素和衰老的作用
Claudia DAnna,Caterina Di Sano,Angela Marina Montalbano et al.
Claudia DAnna et al.
Background: Airway diseases, including asthma and chronic obstructive pulmonary disease (COPD) are global public health burden due to their high prevalence, morbidity, and mortality. Although these conditions are clinical...
Patient-Anchored Cough Visual Analogue Scale and Leicester Cough Questionnaire Thresholds for Cough Control Classification in Chronic Cough [0.03%]
基于患者的慢性咳嗽咳声视觉模拟评分及 Leicester 咳嗽问卷的咳嗽控制分类阈值研究
Minkyo Suh,Ji-Yoon Oh,Ha-Kyeong Won et al.
Minkyo Suh et al.
Purpose: The cough severity visual analogue scale (VAS) and the Leicester Cough Questionnaire (LCQ) are commonly used in chronic cough. While continuous scores are useful for tracking change, categorization is needed to d...
Association of Diaphragmatic Crus Thickness Assessed by Computed Tomography with Diaphragmatic Excursion and Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease [0.03%]
慢性阻塞性肺疾病患者膈肌厚度与膈肌活动度及运动能力的关系:一项体层摄影研究
Masashi Shiraishi,Yuji Higashimoto,Hiroki Mizusawa et al.
Masashi Shiraishi et al.
Purpose: Diaphragmatic dysfunction contributes to exercise intolerance in chronic obstructive pulmonary disease (COPD). Although diaphragmatic excursion during deep breathing (DEmax) is associated with exercise capacity, ...
Persistent Urinary Incontinence in Female Patients with Chronic Cough: A 6-month Longitudinal Analysis [0.03%]
慢性咳嗽女性患者的持续性尿失禁:一项为期6个月的纵向分析
Hwa Young Lee,Seung-Eun Lee,Noeul Kang et al.
Hwa Young Lee et al.
Introduction: Urinary incontinence (UI) is common among female patients with chronic cough; however, factors associated with persistent UI and related clinical outcomes remain insufficiently defined. ...
FeNO as a Treatable Trait in Chronic Cough: Insights from the PROCOUGH Study [0.03%]
来自PROCOUGH研究的呼出气一氧化氮(FeNO)作为慢性咳嗽可治疗特征的新见解
Mustafaa Wahab,Elena Kum,Nermin Diab et al.
Mustafaa Wahab et al.
Purpose: Type 2 (T2) inflammatory biomarkers are established therapeutic targets in asthma and non-asthmatic eosinophilic bronchitis (NAEB), but their relevance in chronic cough remains unclear. Therefore, the objective o...