rs2032582 polymorphism of ATP binding cassette subfamily B member 1 affect the susceptibility of inflammatory bowel disease: a systematical meta-analysis based on 14,876 subjects [0.03%]
ABCB1基因 rs2032582多态性与炎症性肠病易感性的关联：基于14876例受试者的系统评价和meta分析
Hongwei Chen,Hesong Zhang,Guixiang Tao
Hongwei Chen
Background: Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing global incidence. This meta-an...
Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials [0.03%]
IL-23抑制剂治疗中重度溃疡性结肠炎患者的安全性和有效性：随机对照试验的系统评价和meta分析
Hamza Muhammad Amin,Sundas Hasan,Reem Abukhater et al.
Hamza Muhammad Amin et al.
Background and objective: Targeting the interleukin-23 (IL-23) pathway is an emerging therapeutic strategy for moderate to severe ulcerative colitis (UC). This systematic review and meta-analysis evaluated the efficacy an...
Risk factors for bacterial translocation after loop ileostomy closure in patients with colorectal cancer [0.03%]
结肠癌患者回肠袢式造口关闭术后细菌易位的风险因素分析
Toshiyuki Adachi,Yusuke Inoue,Satomi Okada et al.
Toshiyuki Adachi et al.
Purpose: Although rare, septic shock can develop following the closure of an ileostomy created during colorectal cancer surgery. In such cases, bacterial translocation (BT) is considered the primary diagnosis, and appropr...
Impact of age on short-term outcomes and oncologic prognosis after radical surgery for colorectal cancer over 60 [0.03%]
年龄对老年结直肠癌根治术后近期疗效和肿瘤预后影响的临床分析（60岁以上）
Jian-Jun Chen,Zhu-Lin Li,Yong Yang et al.
Jian-Jun Chen et al.
Purpose: Colorectal cancer (CRC) is becoming increasingly common in adults ≥ 60 years old, yet postoperative prognosis of curative-intent surgery for the advanced elderly (≥ 80 years) remains controversial. ...
Histological assessment of radiotherapy-induced injury in the anal canal: an exploratory study [0.03%]
放射治疗引起的肛管损伤的组织学评估：一项探索性研究
Aikaterini Leventi,Paul Sibbons,Alexia Tsigka et al.
Aikaterini Leventi et al.
Purpose: Faecal incontinence (FI) is a common and debilitating late effect of chemoradiotherapy in patients with anal cancer. While its clinical relevance is well recognized, the underlying histopathological mechanisms re...
Development and application of an artificial intelligence-assisted endoscopic system for automatic and accurate diagnosis of colorectal ulcers [0.03%]
一种人工智能辅助内镜系统在结肠溃疡自动准确诊断中的研发和应用
Zhihang Yu,Xinyuan Liu,Xinkun Yu et al.
Zhihang Yu et al.
Objectives: Crohn's disease (CD), ulcerative colitis (UC), intestinal Behçet's disease (BD), intestinal tuberculosis (ITB), and primary intestinal lymphoma (PIL) are major intestinal disorders that frequently present wit...
TNF antagonists withdrawal is not advised in patients with inflammatory bowel disease in remission: a systematic review and meta-analysis of randomized controlled trials [0.03%]
维持缓解状态的炎症性肠病患者无需终止肿瘤坏死因子拮抗剂治疗：随机对照试验的系统评价和meta分析
Ahmed Adekunle Owolabi,Iqra Qazi,Nadia Ahmed et al.
Ahmed Adekunle Owolabi et al.
Background: Tumor necrosis factor (TNF) antagonists are central to the management of inflammatory bowel disease (IBD), but concerns regarding long-term safety, infection risk, and costs have prompted interest in treatment...
MRI-defined high-risk rectal cancer patients: comparison of treatment response and survival outcomes between total neoadjuvant therapy and neoadjuvant chemoradiotherapy-a propensity score matched analysis [0.03%]
基于MRI的高危直肠癌患者的治疗反应和生存结局：全新辅助治疗与新辅助放化疗的倾向性匹配分析
Ruiting Li,Meng Zhao,Qiong Ma et al.
Ruiting Li et al.
Purpose: This study evaluated whether total neoadjuvant therapy (TNT), compared to neoadjuvant chemoradiotherapy (nCRT), improves response and prognosis in magnetic resonance imaging (MRI)-defined high-risk patients with ...
Longitudinal assessment of quality of life and symptom burden in locally advanced rectal cancer patients receiving IMRT-based preoperative radiotherapy: A prospective cohort study [0.03%]
基于术前放射治疗的局部晚期直肠癌患者的生活质量和症状负担纵向评估：前瞻性队列研究
Christina G Truelsen,Camilla S Kronborg,Anne Ramlov et al.
Christina G Truelsen et al.
Purpose: Preoperative radiotherapy (pRT) for rectal cancer (RC) reduces local recurrence rates. However, treatment-induced side effects may compromise patient-reported quality of life (QoL). This study aimed to report lon...
Defining key interventions for rectal cancer surgery: a literature review and expert panel consensus [0.03%]
结肠癌手术关键操作定义：文献回顾与专家共识达成
Cédric Schraepen,Gabriele Bislenghi,Kris Vanhaecht et al.
Cédric Schraepen et al.
Background: Despite advances in minimally invasive techniques and widespread adoption of Enhanced Recovery Programs (ERPs), rectal cancer surgery continues to pose significant challenges due to anatomical limitations, ris...