Mucosal fungal dysbiosis is associated with early postoperative endoscopic recurrence after bowel resection for Crohn's disease [0.03%]
肠切除术后黏膜真菌微生态失衡与克罗恩病患者早期内镜复发相关性研究
Liangdong Zheng,Lei Zhao,Jie Zhang et al.
Liangdong Zheng et al.
Purpose: Anastomotic recurrence after ileocolectomy for Crohn's disease may be related to the gut microbiota, but the role of mycobiota remains unclear. This study aimed to investigate associations between mucosal mycobio...
Comparison and analysis of the immune landscape at the tumour invasion front in patients with pMMR/MSI-H and pMMR/MSS colorectal cancer [0.03%]
pMMR/MSI-H和pMMR/MSS结直肠癌患者肿瘤浸润边缘免疫图谱的比较分析
Miao Shen,Guoqun Chen,Fengli Cai et al.
Miao Shen et al.
Objectives: This study aims to compare and analyse the immune landscape at the tumour invasion front in patients with colorectal cancer (CRC) with proficient mismatch repair (pMMR) and deficient mismatch repair (dMMR). ...
Long-term outcomes of stapled haemorrhoidopexy versus conventional haemorrhoidectomy: An updated systematic review, meta-analysis and trial-sequential analysis of randomized controlled trials [0.03%]
吻合器痔上黏膜环切钉合术与传统外剥内扎术治疗痔疮的长期疗效：系统评价、meta 分析及试验序列分析
Sara Lauricella,Francesco Brucchi,Gianluca Mascianà et al.
Sara Lauricella et al.
Purpose: Stapled haemorrhoidopexy (SH) offers well-established short-term advantages over conventional haemorrhoidectomy (CH), but its long-term effectiveness remains controversial. This systematic review and meta-analysi...
Improving dietary fiber intake is associated with a declining burden of early-onset colorectal cancer: a three-decade comparative analysis in China and globally [0.03%]
改善膳食纤维摄入与早发性结直肠癌负担下降有关：中国和全球三十年来的比较分析
Guanmin Cui,Kai Jing,Yunxia Li et al.
Guanmin Cui et al.
Background: The global incidence of early-onset colorectal cancer (EOCRC) is rising. We compared trends in dietary fiber intake, a key modifiable risk factor, and its attributable EOCRC burden among young adults in China ...
Machine learning-based integration of tumor deposit molecular signatures improves prognostic stratification in colon adenocarcinoma [0.03%]
基于机器学习整合肿瘤附属物分子标志物改善结肠腺癌预后分层
Jiaying Wu,Jiaming Wu,Zhen Zheng et al.
Jiaying Wu et al.
Background: Colon adenocarcinoma (COAD) remains a leading cause of cancer-related mortality worldwide. Although tumor deposits (TDs) are established prognostic indicators, their molecular characteristics and potential for...
Change in faecal incontinence pattern after gastric bypass surgery: related to change in anal sphincter thickness? [0.03%]
胃旁路手术后粪失禁模式的变化与肛门括约肌厚度变化有关吗？
Jeff Wennerlund,David Thalén,Anton Östevind et al.
Jeff Wennerlund et al.
Purpose: Faecal incontinence is common in persons with severe obesity. Little is known about how the thicknesses of the internal anal sphincter (IAS) and the external anal sphincter (EAS) change in relation to weight loss...
Endoscopic submucosal dissection versus endoscopic mucosal resection for the treatment of rectal tumors extending to the dentate line: a systematic review and meta-analysis [0.03%]
内镜下黏膜切除和内镜粘膜下挖除治疗肿瘤累及齿线的直肠肿物的系统评价和meta分析
Cong Ding,Jianfeng Yang,Jing Yang et al.
Cong Ding et al.
Purpose: We performed a systematic review and meta-analysis to compare the efficacy and safety of endoscopic submucosal dissection (ESD) with those of endoscopic mucosal resection (EMR) for rectal tumors extending to the ...
An interpretable machine learning model based on MRI radiomics and GAME score for predicting early recurrence after thermal ablation in colorectal liver metastases [0.03%]
基于MRI影像组学和GAME评分的预测结直肠癌肝转移微波消融后早期复发的可解释机器学习模型
Yaqing Kong,Lijuan Wan,Xiaoning Yue et al.
Yaqing Kong et al.
Objective: To develop and validate machine learning models based on preoperative magnetic resonance imaging(MRI) and baseline clinical characteristics for predicting early recurrence(ER) in patients with colorectal liver ...
The Levator Hiatus Area detected by 3D-TPUS as an indicator of rectal prolapse severity [0.03%]
三维经直肠超声测量的闭孔区域高度对直肠脱垂严重程度的预测价值研究
Danqi Shao,Jianping Qiu,Junli Yu et al.
Danqi Shao et al.
Purpose: Rectal prolapse (RP) is a clinically significant condition with vaginal delivery as a major risk factor, especially in elderly females, needs precise evaluation for guiding treatment. Given the limitations of cur...
The subtype identification of colorectal cancer and construction of the risk model based on cholesterol synthesis-related genes to predict prognosis and guide immunotherapy [0.03%]
基于胆固醇合成相关基因的结直肠癌亚型鉴定及预后风险模型构建以预测预后和指导免疫治疗
Qing Sun,Ruolin Sun,Bokun He et al.
Qing Sun et al.
Background: Colorectal cancer (CRC) is a common malignant tumor worldwide. The cholesterol synthesis (CS) pathway is crucial in the occurrence and development of cancer. This study aims to predict the prognosis of CRC pat...