Long-term outcome of children with acute lymphoblastic leukemia after hematopoietic stem cell transplantation based on ex-vivo alpha-beta T cell depletion [0.03%]
体外αβT细胞去除后造血干细胞移植治疗急性淋巴细胞白血病的远期疗效分析
Larisa Shelikhova,Maria Ilyushina,Rimma Khismatullina et al.
Larisa Shelikhova et al.
Hematopoietic stem cell transplantation (HSCT) is a curative option for children with high-risk acute lymphoblastic leukemia (ALL). This retrospective single-center study analyzed 236 pediatric ALL patients in complete remission who underwe...
Successful treatment of relapsed FLT3-mutated donor cell-derived MDS/AML with FLT3 inhibitor gilteritinib [0.03%]
FLT3抑制剂吉瑞替尼治疗复发的FLT3突变供体细胞衍生MDS/AML患者取得成功
Mana Kawano,Hiroyoshi Kunimoto,Akihiko Izumi et al.
Mana Kawano et al.
Donor cell-derived myelodysplastic syndrome/acute myeloid leukemia is a rare but serious complication of allogeneic hematopoietic stem cell transplantation, and its optimal treatment has not been established. Here, we report a case of a 44-...
Overall survival with momelotinib vs. best available therapy in patients with ruxolitinib-experienced myelofibrosis: a matching-adjusted indirect comparison [0.03%]
莫莫替尼与最佳可用疗法在鲁索利替尼治疗后疾病进展的骨髓纤维化患者中的总生存期：事后匹配调整的间接比较分析
Francesca Palandri,Venediktos Kapetanakis,Balázs Dobi et al.
Francesca Palandri et al.
The Janus kinase (JAK) inhibitor ruxolitinib is a standard first-line therapy for patients with symptomatic and/or intermediate- to high-risk myelofibrosis (MF). However, the majority of patients discontinue ruxolitinib within 5 years of in...
Mechanisms of resistance to bruton's tyrosine kinase inhibitors: synergistic effects of tumor microenvironment regulation and signaling pathways [0.03%]
Bruton酪氨酸激酶抑制剂耐药机制：肿瘤微环境调节和信号转导通路的协同作用
Xinyu Dong,Shujun Tang,Miaohong Chen et al.
Xinyu Dong et al.
It is widely acknowledged that B-cell lymphoma represent a significant threat to human health, and Bruton Tyrosine Kinase inhibitors (BTKi) have been shown to exhibit superior clinical efficacy and safety in comparison to conventional chemo...
Machine learning based on clinical and gene expression data assists in survival prediction and treatment optimization for diffuse large B-Cell lymphoma patients [0.03%]
基于临床和基因表达数据的机器学习有助于弥漫性大B细胞淋巴瘤患者的生存预测和治疗优化
Junwei Lin,Weifeng Lv,Huixing Cai et al.
Junwei Lin et al.
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and common subtype of non-Hodgkin lymphoma (NHL). Despite the availability of several risk stratification tools, substantial room for improvement in personalized prognostic prediction s...
Pomalidomide re-exposure after drug-related severe hypothyroidism: a case report [0.03%]
类固醇相关重度甲状腺功能减退症患者的帕默利多重复治疗：一例报告
Francesca Bartolomei,Tommaso Za,Francesca Di Landro et al.
Francesca Bartolomei et al.
Pomalidomide, an analogue of lenalidomide and thalidomide, has shown significant activity in treating relapsed refractory multiple myeloma (MM). Due to its oral formulation and favorable safety profile, pomalidomide is generally well tolera...
Assessment of characteristics and treatment patterns of adult patients with acquired aplastic anemia in Turkiye (PLANE-TR) [0.03%]
土耳其成人获得性再生障碍性贫血患者的特征和治疗模式评估（PLANE-TR）研究
Eren Gunduz,Turgay Ulas,Fahir Ozkalemkas et al.
Eren Gunduz et al.
Acquired aplastic anemia (AA) is a rare blood disorder causing hypocellular bone marrow due to immune damage to hematopoietic stem cells, leading to low blood cell counts. This study investigates the demographics, treatment patterns, and cl...
Multicenter Study
Annals of hematology. 2026 Feb 20;105(4):130. DOI:10.1007/s00277-026-06871-y 2026
A novel frameshift deletion in SLC25A38 and its role in mitochondrial dysfunction: A case study of sideroblastic anemia in a child from Iran [0.03%]
SLC25A38 框移缺失及其在铁粒幼细胞性贫血患儿线粒体功能障碍中的作用：一例研究
Elaheh Hasani,Maryam Naghinejad,Moein Kohkalani et al.
Elaheh Hasani et al.
Sideroblastic anemia (SA) is a rare hematological condition characterized by the accumulation of iron in the mitochondria of erythroid precursor cells, resulting in the formation of sideroblastic rings. It occurs in both inherited and acqui...
The optimal conditioning intensity of stem cell transplantation for acute myeloid leukemia in complete remission [0.03%]
完全缓解的急性髓系白血病患者进行干细胞移植的最佳预处理强度
Yoshimitsu Shimomura,Sho Komukai,Tetsuhisa Kitamura et al.
Yoshimitsu Shimomura et al.
This study aimed to identify patient groups in which myeloablative conditioning (MAC) or reduced-intensity conditioning (RIC) regimens induced superior progression-free survival (PFS) in patients with acute myeloid leukemia (AML) in complet...
Risk of vaso-occlusive crisis requiring hospitalization in sickle cell disease patients in brazil: retrospective cohort study of real-world data [0.03%]
巴西镰状细胞病患者需要住院的血管闭塞危象风险：真实世界数据的回顾性队列研究
Vanessa Maia de Almeida Barros,Ana Cristina Silva-Pinto,Patricia Gomes Moura et al.
Vanessa Maia de Almeida Barros et al.
Sickle cell disease (SCD) is associated with several complications, high health-care-related costs and reduced life expectancy. This study addresses the high incidence of vaso-occlusive crises (VOC) in patients with SCD in Brazil, a conditi...