Thrombotic thrombocytopenic purpura as a complication of pembrolizumab: a case report and literature Review [0.03%]
帕博利珠单抗引起的溶血性尿毒症综合征合并血栓性血小板减少性紫癜1例及相关文献复习
Gregory Palega,Ihab Ahmad Al-Rikabi,Malgorzata Kopaczek-Styczen et al.
Gregory Palega et al.
The success of immune checkpoint inhibitors (ICIs) has revolutionized oncology, with an increasing number of patients receiving treatment every year. However, this progress has been accompanied by a rise in immune-related adverse events (ir...
Diagnostic accuracy of the sickle SCAN® rapid test for neonatal screening of sickle cell disease in Lubumbashi, Democratic Republic of the Congo [0.03%]
刚果民主共和国卢布扎巴希市新生儿镰状细胞病筛查的SICKLE SCAN®快速检测诊断准确性评估
Tina Katamea,Olivier Mukuku,André Kabamba Mutombo et al.
Tina Katamea et al.
Sickle cell disease (SCD) is a common and potentially life-threatening haematological disorder. In high-income countries, universal newborn screening and timely interventions have markedly reduced infant mortality. In contrast, in low-resou...
Resolution of vanishing bile duct syndrome in a patient associated with refractory hodgkin lymphoma following Anti-PD-1 therapy: a case report and literature review [0.03%]
抗PD-1治疗难治性霍奇金淋巴瘤后胆管消失综合征消退1例报告及文献复习
Yi-Ching Lin,Wan-Chen Hsieh,Yu-Hsuan Tuan et al.
Yi-Ching Lin et al.
Vanishing bile duct syndrome (VBDS) is a rare, and often fatal complication of Hodgkin lymphoma (HL), characterized by progressive intrahepatic bile duct loss and severe cholestasis. Management remains ill-defined, particularly in patients ...
Hemostatic rescue with rFVIIa in Bernard-Soulier syndrome refractory to HLA-matched platelet transfusion [0.03%]
人源化七因子rFVIIa治疗匹配供体血小板无效的布- Soulier综合征患者出血急救研究
Yusuke Okamoto,Chisaki Mizumoto,Kouhei Yamashita et al.
Yusuke Okamoto et al.
We report the case of a man in his 50’s diagnosed with Bernard-Soulier syndrome (BSS) in childhood who developed refractory gluteal bleeding following a fall accident. The patient underwent four hematoma evacuation procedures and multiple ...
Treatment Outcomes and Factors Affecting Survival in Pediatric Acute Myeloid Leukemia [0.03%]
儿童急性髓系白血病的治疗结局及影响生存的因素分析
Yurday Öncül,Arzu Akyay,Bengü Macit et al.
Yurday Öncül et al.
This study examined the clinical, genetic, and treatment response characteristics of pediatric patients with acute myeloid leukemia (AML) treated according to the 2004 and 2012 AML-BFM protocols. This study aimed to determine survival outco...
Long-term efficacy and safety of low-dose rituximab in immune thrombocytopenia: a multicentre, prospective, open-label, randomised controlled trial [0.03%]
利妥昔单抗小剂量方案治疗免疫性血小板减少症的长期疗效和安全性：多中心、前瞻性、开放标签、随机对照试验
Yunfei Chen,Jiaying Liu,Jiawen Dai et al.
Yunfei Chen et al.
Around 60–80% of patients with immune thrombocytopenia (ITP) experience disease relapse after stopping corticosteroids. Rituximab (RTX) is an effective second-line treatment. Low-dose RTX has shown similar efficacy to standard dose, but th...
The impact of venetoclax treatment duration on efficacy and hematologic toxicity in acute myeloid leukemia: a systematic review and meta-analysis [0.03%]
维奈克拉治疗持续时间对急性髓系白血病疗效和血液学毒性的 影响：系统评价和 meta 分析
Ying Pan,Yuanyuan Shen,Sihan Miao et al.
Ying Pan et al.
Venetoclax (VEN) combined with hypomethylating agents (HMA) is a standard treatment for unfit acute myeloid leukemia (AML) patients, but the conventional 28-day cycle often leads to prolonged cytopenias and infection risks. Recent studies s...
Identification of the Philadelphia-like subgroup in Turkish pediatric patients with acute lymphoblastic leukemia [0.03%]
急性淋巴细胞白血病土耳其儿童患者的费城样亚组的鉴定
Ecem Efendi Erdem,Gulsah Cecener,Ufuk Unal et al.
Ecem Efendi Erdem et al.
Ph-like ALL, a high-risk subgroup of B-cell ALL, is associated with a poor prognosis. The genetic diversity observed across different ethnicities underscores the importance of population-specific studies to gain a deeper understanding of it...
Superiority of high-dose cytarabine-based mobilisation over cyclophosphamide or plerixafor in primary CNS lymphoma [0.03%]
高剂量阿糖胞苷动员优于环磷酰胺或普乐明用于原发中枢神经系统淋巴瘤
Qing Li,Lili Zhu,Yan Ma et al.
Qing Li et al.
High-dose chemotherapy with autologous stem cell transplantation (ASCT) is a key consolidative therapy for primary central nervous system lymphoma (PCNSL). However, the optimal regimen for mobilizing haematopoietic stem cells remains undefi...
Comparative Study
Annals of hematology. 2026 Feb 25;105(4):137. DOI:10.1007/s00277-026-06749-z 2026
Potential utility of PPARγ agonists in targeting chronic myeloid leukemia stem cells [0.03%]
PPARγ激动剂针对慢性髓性白血病干细胞的潜在作用机制研究
Basma Atef,Shaimaa El-Ashwah,Layla M Saleh et al.
Basma Atef et al.
Tyrosine kinase inhibitors (TKIs) have transformed the treatment of chronic myeloid leukemia (CML), yet persistent leukemia stem cells (LSCs) remain a barrier to cure. PPARγ agonists like pioglitazone have been proposed to enhance eradicat...