Current evidence and strategies for bridging therapy in CD19-directed chimeric antigen receptor T-cell therapy for relapsed/refractory large B-cell lymphomas [0.03%]
Jie Lv,Yan Xie,Chen Zhang et al.
Jie Lv et al.
CD19-directed chimeric antigen receptor T-cell (CAR T-cell) therapy has markedly improved the prognosis of patients with relapsed or refractory large B-cell lymphoma (R/R LBCL). However, disease progression during the manufacturing period r...
2g/m2 Ara-c induced more favorable outcome than 1g/m2 Ara-c in CLAG treatment for refractory or relapsed acute myeloid leukemia without increase toxicity: a multicenter propensity score matching analysis [0.03%]
Na Liu,Yan-Ru Ma,Jia-Nan Pang et al.
Na Liu et al.
This study compared the efficacy and toxicity of two cytarabine doses (1 g/m² vs. 2 g/m²) within the CLAG regimen for relapsed/refractory acute myeloid leukemia (R/R AML) patients. In this multicenter retrospective analysis, 183 R/R AML p...
Real-world effectiveness of bortezomib maintenance following VMP induction in transplant-ineligible multiple myeloma: a target trial emulation study [0.03%]
Jung Yeon Lee,Suein Choi,Seungpil Jung et al.
Jung Yeon Lee et al.
Bortezomib-melphalan-prednisone (VMP) is an established induction regimen for transplant-ineligible newly diagnosed multiple myeloma (NDMM), yet optimal post-induction strategies remain unclear. This study evaluated the effectiveness of bor...
Development and validation of the ultrasound-based radiomics and deep learning prognostic models for diffuse large B-cell lymphoma [0.03%]
Yue Yu,Siqin Liao,Hongda Su et al.
Yue Yu et al.
Lymphoma includes fatal hematological malignancies, with diffuse large B-cell lymphoma (DLBCL) as the most common aggressive non-Hodgkin lymphoma subtype. Accurate early identification of high-risk DLBCL patients is key for individualized t...
Elevated tricuspid regurgitation velocity in adults with sickle cell disease and HbAA controls in Kinshasa, Democratic Republic of the Congo: a comparative cross-sectional study [0.03%]
Yannick Mompango Engole,Brady Makanzu,Tresor Swambulu Mvunzi et al.
Yannick Mompango Engole et al.
Pulmonary hypertension is a severe complication of sickle cell disease (SCD) and is associated with increased morbidity and mortality. Elevated tricuspid regurgitation velocity (TRV) assessed by echocardiography is commonly used as a screen...
Lalitphan Nimmankiatkul,Supika Kritsaneepaiboon,Natee Ina et al.
Lalitphan Nimmankiatkul et al.
Sarcopenia and sarcopenic obesity are increasingly recognized sequelae of anticancer therapy in children, yet a consensus definition remains elusive. Diminished skeletal muscle area (SMA) and increased adiposity have been associated with po...
Treatment of Burkitt lymphoma in real-world setting: findings on 104 consecutive cases diagnosed and treated in Kazakhstan over the last decade [0.03%]
Akmaral Jazyltayeva,Nazarii Shokun,Ayazhan Umutbayeva et al.
Akmaral Jazyltayeva et al.
We investigated treatment outcomes, relapse risk, and survival in 104 consecutive patients with non-endemic Burkitt lymphoma (BL) diagnosed and treated in Kazakhstan between 2013 and 2024 in a real-world setting. This was a retrospective, c...
Restless legs syndrome in chronic myeloid leukemia: an overlooked condition with a significant impact on health-related quality of life [0.03%]
Turgut Gürer,Ulgar Boran Günay,Berkay Kılıç et al.
Turgut Gürer et al.
Restless legs syndrome (RLS) is a common but often overlooked cause of sleep disturbance and discomfort during rest. The prevalence of RLS remains unknown in chronic myeloid leukemia (CML). This study explores its frequency, clinical releva...
Lipegfilgrastim for primary prophylaxis of febrile neutropenia in patients treated for advanced-stage classical hodgkin lymphoma: successful outcomes from a multicenter cohort study [0.03%]
Claudia Giordano,M Picardi,F Esposito et al.
Claudia Giordano et al.
In patients with classical Hodgkin lymphoma (c-HL) undergoing ABVD chemotherapy for advanced disease, the optimal strategy to prevent febrile neutropenia (FN)—defined as fever ≥ 38 °C with absolute neutrophil count (ANC) < 1000/mm³—rem...
Burden of disease for multiple myeloma in China and the Asia-Pacific region, 1990-2021: a systematic analysis of the Global Burden of Disease (GBD) 2021 study [0.03%]
中国和亚太地区1990年至2021年多发性骨髓瘤疾病负担：《全球疾病负担（GBD）2021》研究报告的系统分析
Sen-Xin Wang,Tao Luo,Ni Yang et al.
Sen-Xin Wang et al.
This project tracks Asia-Pacific multiple myeloma (MM) disease burden from 1990 to 2021. This research predicts incidence and death trends due to aging populations, healthcare resource disparities, gender, regional differences, and health i...