Laboratory and genetic characteristic associated with gallbladder-related outcomes in sickle cell disease in Brazil: results from the REDS-III multicenter cohort study [0.03%]
巴西镰状细胞病患者胆囊相关结局的实验室和基因特征:来自REDs-III多中心队列研究的结果
André Rolim Belisário,Mina Cintho Ozahata,Isabel Cristina Gomes Moura et al.
André Rolim Belisário et al.
Sickle cell disease (SCD) is a hereditary disorder characterized by HBB variants, leading to chronic hemolytic anemia and vaso-occlusion. Hepatobiliary complications, including cholelithiasis, are common but underreported. This study invest...
Comprehensive geriatric assessment (CGA) scale does not effectively identify elderly AML patients suitable for intensive induction chemotherapy - a multicenter study from Polish Adult Leukemia Group [0.03%]
全面的姑息治疗评估量表无法有效识别适合强化诱导化疗的老年急性髓系白血病患者-来自波兰成人急性 leukemia 组的研究
Bożena Katarzyna Budziszewska,Michał Łomiak,Joanna Barankiewicz et al.
Bożena Katarzyna Budziszewska et al.
Standard scales, such as ECOG Performance Status, Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI), and Activities of Daily Living (ADL), are commonly used to stratify patients with acute myeloid leukemia (AML) for intensive ch...
Short-course high-dose cytarabine consolidation therapy before allogeneic hematopoietic stem cell transplantation improves 2-year relapse-free survival but not overall survival in patients with acute myeloid leukemia: a single-center retrospective study [0.03%]
异基因造血干细胞移植前短程大剂量阿糖胞苷巩固治疗可改善急性髓系白血病患者两年无复发生存率但不能提高总体生存率:单中心回顾性研究
Yu Ma,Yanyan Cheng,Yuting Sun et al.
Yu Ma et al.
The role of consolidation therapy and the optimal number of consolidation cycles prior to allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients with acute myeloid leukemia (AML) remains controversial. We retrospectively...
Machine learning and AI-Assisted red blood cell morphology analysis for effective thalassemia screening [0.03%]
基于机器学习和人工智能辅助的红细胞形态学分析在地中海贫血筛查中的应用研究
Ying Gui,Weiwei Chen,Yuangang Su et al.
Ying Gui et al.
Background: Thalassemia is an inherited autosomal recessive hematologic disorder characterized by chronic hemolytic anemia due to impaired synthesis of globin chains. A three-level prevention system has effectively reduced the birth rate of...
Beyond medical costs: a call for integrating psychosocial support into lymphoma care policy [0.03%]
超越医疗费用:构建政策以整合心理社会支持淋巴瘤患者发声
Jianren Wen,Jingxuan Hu,Guohui Zou
Jianren Wen
Intermediate doses cytarabine after induction with CPX-351 for patients with secondary AML: safety and efficacy [0.03%]
CPX-351诱导后采用 intermediate剂量的阿糖胞苷治疗继发性急性髓系白血病患者的疗效和安全性
Salvatore Perrone,Andrea Corbingi,Calogero Vetro et al.
Salvatore Perrone et al.
Acute myeloid leukemia (AML), especially therapy-related (t-AML) or secondary AML (s-AML), presents complex therapeutic challenges. CPX-351, a liposomal formulation of cytarabine and daunorubicin, has demonstrated superior outcomes compared...
Venetoclax and Blinatumomab for adult patients with relapsed/refractory or MRD positive Ph-negative B-cell precursor ALL: phase I part of the GMALL-BLIVEN trial [0.03%]
成人复发/难治性或MRD阳性Ph阴性B细胞急性淋巴细胞白血病患者的Venetoclax和Blinatumomab治疗:GMALL-BLIVEN试验的一期临床研究
Lars Fransecky,Walter Fiedler,Christoph Röllig et al.
Lars Fransecky et al.
Prognosis of adult patients with relapsed/refractory (r/r) or measurable residual disease (MRD)–positive B-precursor acute lymphoblastic leukemia (B-ALL) remains poor. Blinatumomab induces complete remissions (CR) and MRD negativity in a s...
Correction to: Long-term follow-up of predominantly Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukemia in the phase 3 COMMODORE trial [0.03%]
COMMODORE III期临床研究的校正:亚洲复发/难治FLT3突变阳性急性髓系白血病患者的长期随访结果
Bin Jiang,Jian Li,Ligen Liu et al.
Bin Jiang et al.
Published Erratum
Annals of hematology. 2026 Feb 12;105(3):108. DOI:10.1007/s00277-026-06880-x 2026
Corilagin induces pyroptosis in AML cells by activating the TXNIP-caspase-3-GSDME pathway [0.03%]
CORILAGIN通过激活TXNIP-半胱天冬酶3-GSDME途径诱导急性髓系白血病细胞焦亡
Ganlu Feng,Yizhen Li,Ying Wang et al.
Ganlu Feng et al.
Acute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion of myeloid progenitors in the bone marrow, resulting in impaired hematopoiesis. AML remains challenging due to frequent disease recurrence and limi...
Chronic lymphocytic leukemia with IGH/BCL2 fusion and clonal heterogeneity: phenotypic and molecular profiling analysis of a rare case [0.03%]
IGH/BCL2融合及克隆异质性慢性淋巴细胞性白血病罕见病例的表型和分子特征分析
Ting Zhang,Dan Liu,Fanggang Ren et al.
Ting Zhang et al.
Clonal heterogeneity within chronic lymphocytic leukemia (CLL) has been increasingly recognized as a factor that may influence disease progression, treatment response, and prognosis. Here, we report a rare case of CLL with two distinct B-ce...