Autonomous and non-autonomous phenotypic expression of Notch mutant cells in Drosophila embryogenesis [0.03%]
果蝇胚胎发育中Notch突变细胞的自主性和非自主性表型表达
Isabella Stüttem,José A Campos-Ortega
Isabella Stüttem
Transplantation of single homozygous Notch - cells into the ventral neuroectoderm of Drosophila wild-type embryos reveals a non-autonomous behaviour of these cells. However, mitotic recombination events induced in heterozygous cells in imag...
Cyrus Papan,José A Campos-Ortega
Cyrus Papan
We describe the results of a clonal analysis of spinal cord development in the zebrafish. The data were obtained from embryos in which fluorescent lineage tracer was injected into single cells in the neural plate at the two-somite stage. In...
Fast and efficient egg collection and antibody staining from large numbers of Drosophila strains [0.03%]
快速高效地从大量果蝇品系中收集胚胎和染色抗体
T Hummel,K Schimmelpfeng,C Klämbt
T Hummel
The genetic dissection of any developmental processes requires mutagenesis protocols and the subsequent phenotypic screen of the established mutant strains. Whereas external structures such as the Drosophila cuticle are relatively easy to s...
Expression of the PI4P 5-kinase Drosophila homologue skittles in the germline suggests a role in spermatogenesis and oogenesis [0.03%]
斑马鱼同源Pi4p 5-激酶Skittles在生殖细胞中的表达表明其可能参与精子发生和卵子发生
Stefan Knirr,Ansgar Santel,R Renkawitz-Pohl
Stefan Knirr
We have isolated the Drosophila gene skittles (sktl) which shows homology to members of a novel family of phosphatidylinositol-4-phosphate 5-kinases, including the gene product encoded by the human STM-7.I gene which has been assigned to th...
Spatial-temporal characteristics of intercellular junctions in early zebrafish and loach embryos before and during gastrulation [0.03%]
早期斑马鱼和鲤鱼胚胎闭合前后细胞间连接的时空特性
V Bozhkova,Dmitrii Voronov
V Bozhkova
Injections of lucifer yellow and fluorescein dyes into loach (Misgurnus fossilis) and zebrafish (Danio rerio) embryos were used to analyse the intercellular communication via gap junctions (GJs) and their role in morphogenetic processes dur...
Bone morphogenetic protein-4 expression characterizes inductive boundaries in organs of developing zebrafish [0.03%]
骨形态生成蛋白-4的表达表征了斑马鱼器官发生过程中感应边界的特征
A J Chin,Jau-Nian Chen,Eric S Weinberg
A J Chin
We have cloned and examined the expression pattern of zebrafish bone morphogenetic protein-4 (BMP4) as a start to evaluating signals which might participate in the fashioning of organ systems in this genetically tractable species. The predi...
Yongmei Chen,S T Bissen
Yongmei Chen
Leech embryos undergo invariant patterns of cleavage to yield identifiable cells that have characteristic timings of cell division. To elucidate how these cell-specific differences in cell-cycle timing are regulated, we have isolated a leec...
Tissue-specific expression of an hsc90 gene and nuclear translocation of the HSC90-related protein during amphibian embryogenesis [0.03%]
两栖类胚胎发育过程中组织特异性表达的hsc90基因及与HSC90相关蛋白的核定位
Pascal Coumailleau,Marie-Louise Bonnanfant-Jaïs,Marie-Christine Lainé et al.
Pascal Coumailleau et al.
Expression and distribution of a constitutive member of the 90 kDa heat-shock protein family, named HSC90, was investigated during amphibian embryonic development. By Northern blot analysis, two hsp90 transcripts (2.5 and 3 kb) which displa...
Localized axis determinant in the early cleavage embryo of the goldfish, Carassius auratus [0.03%]
金鱼(Carassius auratus)早期裂胚过程中轴的局部化决定因子
T Mizuno,Etsuro Yamaha,Fumio Yamazaki
T Mizuno
The teleost dorsoventral axis cannot be distinguished morphologically before gastrulation. In order to examine whether the yolk cell affects axis determination, we bisect early cleavage embryos of the goldfish, Carassius auratus. When the v...
K S Sturm,Christoph N Berger,Sheila X Zhou et al.
K S Sturm et al.
The developmental potential of parthenogenetic embryonic stem (P-ES) cells was studied in teratomas and mouse chimaeras. Teratomas derived from P-ES cells contained a mixture of tissue types with variable proportions of specific tissues. Th...