Hiroyuki Nakanishi,Yoshimi Takai
Hiroyuki Nakanishi
Nectins are Ca2+-independent immunoglobulin (Ig)-like cell-cell adhesion molecules, which comprise a family consisting of four members. Nectins have five activities: (1) they show Ca2+-independent cell-cell adhesion activity by homo- and he...
Oliver Einsle,Peter M H Kroneck
Oliver Einsle
Denitrification represents an important part of the biogeochemical cycle of the essential element nitrogen. It constitutes the predominant pathway of the reductive dissimilation of nitrate in the environment. Via four enzymatic reactions, n...
Hans Fritz
Hans Fritz
Wolfgang Baumeister
Wolfgang Baumeister
Cryoelectron tomography opens a window into the inner space of cells. It combines the potential of three-dimensional imaging with a close-to-life preservation of biological samples. Tomograms with molecular resolution are essentially images...
Franz-Ulrich Hartl
Franz-Ulrich Hartl
Comprehensive analysis of metabolites in Corynebacterium glutamicum by gas chromatography/mass spectrometry [0.03%]
气相色谱-质谱联用法全面分析谷氨酸棒杆菌代谢物
Sergey Strelkov,Mirko von Elstermann,Dietmar Schomburg
Sergey Strelkov
An analytical method based on gas chromatography/mass spectrometry was developed for metabolome investigation of Corynebacterium glutamicum. For the first time a fast method for metabolic screening that can be automated is described for thi...
Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice [0.03%]
短期化学敲除GIP受体对小鼠胰岛素分泌、胰岛结构和葡萄糖稳态的影响
Nigel Irwin,Victor A Gault,Brian D Green et al.
Nigel Irwin et al.
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted by endocrine K-cells in response to nutrient absorption. In this study we have utilized a specific and enzymatically stable GIP receptor antagonist, (Pro3)GI...
Comparative Study
Biological chemistry. 2004 Sep;385(9):845-52. DOI:10.1515/BC.2004.110 2004
Inhibition of sequestration of human B2 bradykinin receptor by phenylarsine oxide or sucrose allows determination of a receptor affinity shift and ligand dissociation in intact cells [0.03%]
苯砷酸或蔗糖对人B2缓激肽受体隔离的抑制作用使能够测定完整细胞中结合位点亲合力的变化及配基的解离
Alexander Faussner,Steffen Schuessler,Cornelia Seidl et al.
Alexander Faussner et al.
Depending on their interaction with intracellular proteins, G protein-coupled receptors (GPCR) often display different affinities for agonists at 37 degrees C. Determining the affinity at that temperature is often difficult in intact cells ...
Comparative Study
Biological chemistry. 2004 Sep;385(9):835-43. DOI:10.1515/BC.2004.109 2004
Inhibition of inducible TNF-alpha expression by oxaspirodion, a novel spiro-compound from the ascomycete Chaetomium subspirale [0.03%]
源自半旋孢刺盘孢菌的新Spiro化合物Oxaspirodion抑制诱导型TNF-α表达
Jan Rether,Gerhard Erkel,Timm Anke et al.
Jan Rether et al.
In a search for compounds inhibiting the inducible TNF-alpha promoter activity in T cells, a new spiro-compound, designated oxaspirodion, was isolated from fermentations of the ascomycete Chaetomium subspirale. Oxaspirodion inhibited TNF-al...
Comparative Study
Biological chemistry. 2004 Sep;385(9):829-34. DOI:10.1515/BC.2004.108 2004
An apoptotic inducer, aralin, is a novel type II ribosome-inactivating protein from Aralia elata [0.03%]
刺麻叶萼子蛋白是一种新型的II型核糖体失活蛋白
Makoto Tomatsu,Toshiya Kondo,Takafumi Yoshikawa et al.
Makoto Tomatsu et al.
We recently found that aralin, a novel cytotoxic protein consisting of two subunits, from Aralia elata selectively induces apoptosis in transformed cells as compared to normal cells. Here we report that aralin is a lectin specific for galac...
Comparative Study
Biological chemistry. 2004 Sep;385(9):819-27. DOI:10.1515/BC.2004.107 2004