Glutathione dysregulation and the etiology and progression of human diseases [0.03%]
谷胱甘肽调节异常与人类疾病的发生和进展之间的关系
Nazzareno Ballatori,Suzanne M Krance,Sylvia Notenboom et al.
Nazzareno Ballatori et al.
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH homeostasis are implicated in the etiology and/or progression...
The assembly and activation of kinin-forming systems on the surface of human U-937 macrophage-like cells [0.03%]
人U-937巨噬细胞样细胞表面激肽形成系统的装配和激活
Anna Barbasz,Andrzej Kozik
Anna Barbasz
A complex of three plasma proteins, including the high molecular mass kininogen (HK), prekallikrein (PK), and factor XII (FXII), is known to assemble on cell surfaces to release bradykinin-related proinflammatory peptides (kinins). Only rec...
Expression and localization of atypical PKC isoforms in liver parenchymal cells [0.03%]
非典型PKC同种型在肝实质细胞中的表达与定位
Claudia Stross,Verena Keitel,Elisabeth Winands et al.
Claudia Stross et al.
Members of all three classes of the protein kinase C (PKC) family including atypical PKCzeta (PKCzeta) are involved in central functions of liver parenchymal cells. However, expression and localization of PKCiota (PKCiota), the highly homol...
Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid [0.03%]
人CYP4Z1催化月桂酸和肉豆蔻酸的链中羟基化反应
Andy Zöllner,Calin-Aurel Dragan,Dominik Pistorius et al.
Andy Zöllner et al.
Overexpression of human CYP4Z1, a cytochrome P450 enzyme, has been correlated with poor prognosis in human cancer. However, its catalytic properties are not yet known. We expressed this P450 in Schizosaccharomyces pombe and demonstrate by w...
Regulation of phosphoenolpyruvate carboxylase in PVY(NTN)-infected tobacco plants [0.03%]
PVY(NTN)感染烟草植物中磷酸烯醇式丙酮酸羧化酶的调节作用
Karel Müller,Veronika Doubnerová,Helena Synková et al.
Karel Müller et al.
The effect of viral infection on the regulation of phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1.31) in Nicotiana tabacum L. leaves was studied. PEPC activity was 3 times higher in infected plant leaves compared to healthy plants. Activit...
Interaction of the porcine reproductive and respiratory syndrome virus nucleocapsid protein with the inhibitor of MyoD family-a domain-containing protein [0.03%]
猪繁殖与呼吸综合征病毒核衣壳蛋白与MyoD家族抑制剂-a结构域含蛋白质的相互作用
Cheng Song,Ray Lu,Dorothee Bienzle et al.
Cheng Song et al.
Porcine reproductive and respiratory syndrome (PRRS) virus is an RNA virus that replicates in the cytoplasm, but the viral nucleocapsid (N) protein localizes specifically in the nucleus and nucleolus of virus-infected cells. Nuclear localiz...
Determination of three amino acids causing alteration of proteolytic activities of staphylococcal glutamyl endopeptidases [0.03%]
测定三种引起金黄色葡萄球菌谷氨酸内肽酶蛋白水解活性改变的氨基酸
Takayuki K Nemoto,Toshio Ono,Yu Shimoyama et al.
Takayuki K Nemoto et al.
Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus warneri secrete glutamyl endopeptidases, designated GluV8, GluSE, and GluSW, respectively. The order of their protease activities is GluSE < GluSW
A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15 [0.03%]
完整的KLK活化组学谱分析：KLK9、10和15的激活谱研究
Hyesook Yoon,Sachiko I Blaber,Mekdes Debela et al.
Hyesook Yoon et al.
We previously reported the activation profiles of the human kallikrein-related peptidases (KLKs) as determined from a KLK pro-peptide fusion-protein system. That report described the activity profiles of 12 of the 15 mature KLKs versus the ...
Role of catalytic and non-catalytic subsite residues in ribonuclease activity of human eosinophil-derived neurotoxin [0.03%]
人嗜酸性粒细胞源神经毒素的核糖核酸酶活性中催化和非催化解离位点残基的作用关系研究
Deepa Sikriwal,Divya Seth,Janendra K Batra
Deepa Sikriwal
Human eosinophil-derived neurotoxin (EDN), a secretory protein from eosinophils, is a member of the RNase A superfamily. The ribonucleolytic activity of EDN is central to its biological activities. EDN binds RNA in a cationic cleft, and the...
The influence of linoleic and linolenic acid on the activity and intracellular localisation of phospholipase D in COS-1 cells [0.03%]
月桂酸和亚油酸对COS-1细胞磷脂酶D活性及亚细胞定位的影响
Anja Gemeinhardt,Marwan Alfalah,Thomas Gück et al.
Anja Gemeinhardt et al.
Phospholipase D (PLD) is a receptor-regulated signalling enzyme involved in biological functions, such as exocytosis, phagocytosis, actin dynamics, membrane trafficking, and is considered to be essential for stimulated degranulation of cell...