Marc Jacobsen,Jens Mattow,Dirk Repsilber et al.
Marc Jacobsen et al.
The more we learn about the immune response against tuberculosis (TB) and particularly about the features which distinguish protective immunity, disease susceptibility and pathology, the better we can define biomarkers which correlate with ...
Dendritic cell subtypes as primary targets of vaccines: the emerging role and cross-talk of pattern recognition receptors [0.03%]
树突状细胞亚型作为疫苗的主要靶点：模式识别受体的新兴作用及其相互交流
Szilvia Benko,Zoltán Magyarics,Attila Szabó et al.
Szilvia Benko et al.
Preventive vaccination is the most successful approach against infectious diseases and has a great impact on world health. Vaccines operate through the activation of innate immunity that helps to stimulate antigen-specific T- and B-lymphocy...
Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine [0.03%]
适应性免疫反应与丙型肝炎病毒：从病毒免疫生物学角度到疫苗研发的角度分析
Robert Thimme,Christoph Neumann-Haefelin,Tobias Boettler et al.
Robert Thimme et al.
Hepatitis C virus (HCV) causes chronic infection in approximately two-thirds of cases, leading to chronic hepatitis, liver cirrhosis, liver disease, liver failure, and hepatocellular carcinoma in a substantial proportion of the 170 million ...
Biochemical characterization of the catalytic domains of three different Clostridial collagenases [0.03%]
三种不同产气荚膜梭菌胶原酶催化结构域的生化特性分析
Ulrich Eckhard,Esther Schönauer,Paulina Ducka et al.
Ulrich Eckhard et al.
Clostridial collagenases are used for a broad spectrum of biotechnological applications and represent prime target candidates for both therapy and diagnosis of clostridial infections. In this study, we biochemically characterized the cataly...
Glycosphingolipids from bovine milk and milk fat globule membranes: a comparative study. Adhesion to enterotoxigenic Escherichia coli strains [0.03%]
牛乳和牛奶脂肪球膜中的糖脂：与产肠毒素大肠杆菌的粘附作用比较研究
Fernando Sánchez-Juanes,Josefa M Alonso,Lorena Zancada et al.
Fernando Sánchez-Juanes et al.
Several components of milk fat globule membranes (MFGMs) have been reported to display beneficial health properties and some of them have been implicated in the defense of newborns against pathogens. These observations prompted us to determ...
Comparative Study
Biological chemistry. 2009 Jan;390(1):31-40. DOI:10.1515/BC.2009.003 2009
Active immunisation against gastric inhibitory polypeptide (GIP) improves blood glucose control in an animal model of obesity-diabetes [0.03%]
胃抑制多肽(GIP)的主动免疫改善肥胖糖尿病动物模型血糖控制力
Nigel Irwin,Paula L McClean,Steven Patterson et al.
Nigel Irwin et al.
Recent research suggests that long-term ablation of gastric inhibitory polypeptide (GIP) receptor signalling can reverse or prevent many of the metabolic abnormalities associated with dietary and genetically induced obesity-diabetes. The pr...
Relevance and potential of sphingosine-1-phosphate in vascular inflammatory disease [0.03%]
鞘氨醇-1-磷酸在血管炎性疾病中的作用和潜在机制
Markus van der Giet,Markus Tölle,Burkhard Kleuser
Markus van der Giet
The typical pathological feature of atherosclerosis is inflammation. In the last years, it has become evident that inhibition of inflammation is one important therapeutic option in atherosclerosis. Recently, sphingolipid sphingosine-1-phosp...
Stephan Ludwig
Stephan Ludwig
Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades? [0.03%]
组织丝氨酸蛋白酶家族kallikrein和kallikrein相关肽酶：从鼠到人——过去二十年我们学到了什么？
Judith A Clements
Judith A Clements
The genes encoding the kininogenase, glandular tissue kallikrein, in rodents and man were first described in the mid-1980s. Remarkably, they appeared to be part of a much larger highly conserved family of genes (GK) in rodents, but only had...
Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene BCL2L12 in colon cancer [0.03%]
结肠癌中新的凋亡相关基因BCL2L12的定量表达分析及其预后意义
Christos K Kontos,Iordanis N Papadopoulos,Andreas Scorilas
Christos K Kontos
Apoptosis is a tightly regulated process that plays a critical role in many biological events. Members of the BCL2 (Bcl-2) family of apoptosis-related genes have been found to be differentially expressed in various malignancies and have bee...