The pathogenesis and regulatory role of HIF-1 in rheumatoid arthritis [0.03%]
缺氧诱导因子-1在类风湿关节炎发病机制及调节作用中的研究进展
Han Li,Qi-Yang Wu,Xu-Heng Teng et al.
Han Li et al.
Rheumatoid arthritis (RA) is a prevalent autoimmune disease that involves the overgrowth and inflammation of synovial tissue, leading to the degeneration and impairment of joints. In recent years, numerous studies have shown a close relatio...
COVID-19 vaccination in healthcare workers: Long-term benefits and protection [0.03%]
医护人员的新冠疫苗接种：长期利益与获益保护效果分析
Joanna Szczepanek,Monika Skorupa,Joanna Jarkiewicz-Tretyn et al.
Joanna Szczepanek et al.
Introduction: This study aimed to evaluate the long-term effectiveness of COVID-19 vaccination in healthcare workers by analyzing the population's response to the vaccine after two years, based on anti-SARS-CoV-2 protein ...
Newly diagnosed seropositive rheumatoid arthritis in a 52-year-old man superimposed on long-standing ankylosing spondylitis during secukinumab treatment [0.03%]
一名长期患有银屑病性脊柱关节炎的52岁男性在使用司库奇尤单抗治疗期间出现类风湿关节炎
Jaroslaw Nowakowski,Anna Tomoń,Dorota Telesińska-Jasiówka et al.
Jaroslaw Nowakowski et al.
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are severe chronic inflammatory joint diseases with different immune-mediated mechanisms playing a role in their pathogenesis. Rheumatoid arthritis is an erosive arthritis of periphe...
The role of inflammatory and remodelling biomarkers in patients with non-small cell lung cancer [0.03%]
非小细胞肺癌患者的炎症和重塑生物标志物的作用
Hemn Abdalla Omer,Christer Janson,Kawa Amin
Hemn Abdalla Omer
Introduction: Biomarkers play a crucial role in evaluating the prognosis, diagnosis, and monitoring of non-small cell lung cancer (NSCLC). The aim of this study was to compare the levels of inflammatory and remodelling bi...
Interleukin-1 receptor-associated kinase 2 promotes inflammatory reactions by activating the nuclear factor kappa-B signaling pathway in diabetic nephropathy [0.03%]
白细胞介素-1受体相关激酶2通过激活核因子κB信号通路促进糖尿病肾病的炎症反应
Jingjing Liu,Yingying Xu,Shijie Cheng et al.
Jingjing Liu et al.
Diabetic nephropathy (DN) is a major complication of diabetes. Interleukin-1 receptor-associated kinase 2 (IRAK2) has been implicated in various diseases. This study aimed to investigate the role of IRAK2 in DN progression and its associati...
Notch signaling pathway-based classification of bladder cancer in relation to tumor immune infiltration [0.03%]
基于诺奖信号通路的膀胱癌免疫微环境相关分子分型研究
Yang Bin,Li Guikang,Huang Jin et al.
Yang Bin et al.
Introduction: The role of the Notch signaling pathway in the development of various tumors has received increasing attention, but the relationship between the Notch signaling pathway and the prognosis of bladder cancer ha...
Efficacy of IL-23 inhibitors and IL-12/23 inhibitors in the induction treatment of Crohn's disease: A meta-analysis based on randomized controlled trials [0.03%]
基于随机对照试验的IL-23抑制剂及IL-12/23抑制剂诱导治疗克罗恩病有效性的meta分析研究
Boyang Gao,Haojie Shentu,Suyong Sha et al.
Boyang Gao et al.
Introduction: A growing number of randomized controlled trials (RCTs) have demonstrated the effectiveness of interleukin (IL)-23 and IL-12/23 inhibitors in treating Crohn's disease (CD). This study evaluated the efficacy ...
Hematopoietic stem cell transplantation in a patient with activated phosphoinositide 3-kinase δ syndrome: A case report and literature review [0.03%]
活化磷脂酰肌醇-3-激酶δ综合征患者的造血干细胞移植1例并文献复习
Mateusz P Łyżwa,Karolina Kędziora,Natalia Kałamarz et al.
Mateusz P Łyżwa et al.
Activated phosphoinositide 3-kinase δ syndrome (APDS) is a recently described disease characterized by recurrent infections, lymphoproliferation with a high risk of malignancy, early-onset cytopenia, and a propensity for autoimmune disease...
Association of human leukocyte antigen class II alleles with epithelial cell apoptosis and extracellular matrix production in acute COVID-19 [0.03%]
人类白细胞抗原Ⅱ类等位基因与急性COVID-19患者上皮细胞凋亡和细胞外基质产生的相关性研究
Ieva Vanaga,Oksana Kolesova,Aleksandrs Kolesovs et al.
Ieva Vanaga et al.
Introduction: Pathogenic mechanisms and long-term consequences of COVID-19 require attention in studies on SARS-CoV-2. The association of the severity of COVID-19 with genetic factors, such as human leukocyte antigen (HLA...
Influence of blood sample storage and different types of anticoagulants on results of NK cytotoxicity tests [0.03%]
血液样本保存及不同类型抗凝剂对NK细胞毒试验结果的影响
Katarzyna Popko,Monika Paskudzka,Małgorzata Pieśniewska et al.
Katarzyna Popko et al.
Introduction: Natural killer (NK) cells are important players in the human immune response. Impaired NK function may lead to serious, life-threatening conditions. Defects may be consequences of genetic mutations or result...