KLF14 restrained NLRP3-mediated pyroptosis in sepsis-induced acute lung injury by activating DTX3L [0.03%]
KLF14通过激活DTX3L抑制NLRP3介导的焦亡在脓毒症急性肺损伤中的作用
Xiuying Fan,Libin Tang,Jiawei Xia et al.
Xiuying Fan et al.
Introduction: Acute lung injury (ALI) is characterized by inflammation of the lungs, leading to impaired gas exchange and respiratory distress. This study aimed to investigate the mechanisms underlying the role of Krüppe...
LncSLED1 inhibits monosodium urate-induced macrophage inflammation by promoting Cosmc methylation to upregulate CA72-4 [0.03%]
LncSLED1通过促进Cosmc甲基化来上调CA72-4以抑制单钠尿酸诱导的巨噬细胞炎症
Ning Ren,Xiaojie Qu,Zhenzhen Wang et al.
Ning Ren et al.
Introduction: The core event of gout is intensified macrophage inflammation. Our preliminary research found that carbohydrate antigen 72-4 (CA72-4) secreted by monosodium urate (MSU)-induced human synovial cells (HFLS) co...
Jacek Tabarkiewicz,Paulina Niedźwiedzka-Rystwej,Marlena Tynecka et al.
Jacek Tabarkiewicz et al.
RAB40C regulates SNX9 stability via the ubiquitin-proteasome system and modulates the Hippo signaling pathway of prostate adenocarcinoma [0.03%]
RAB40C通过泛素-蛋白酶体系统调节SNX9稳定性并调控前列腺腺癌中的Hippo信号通路
Liang Qin,Ning Yang,Fan Yang et al.
Liang Qin et al.
Introduction: Aim of the study was to investigate the roles and interaction mechanisms of RAB40C and SNX9 in prostate adenocarcinoma (PRAD) progression and their impact on the Hippo signaling pathway. PRAD is a significan...
N6-methyladenosine modification of CBLB affects LPS-induced endoplasmic reticulum stress in alveolar epithelial cells [0.03%]
CBLB的N6-甲基腺苷修饰影响LPS诱导的肺泡上皮细胞内质网应激反应
Bing Huang,Fangwei Chen,Guochao He et al.
Bing Huang et al.
Introduction: Acute lung injury (ALI) is defined as an acute hypoxic respiratory insufficiency that arises from injury to alveolar epithelial cells. The suppression of endoplasmic reticulum stress (ERS) was reported to pr...
Lactylated chitinase-3-like protein 1 promotes the development of sepsis [0.03%]
乙酰化半乳糖基化溶菌酶3型类似蛋白1促进脓毒症的发展
Shiliang Wei,Xin Wang,Hailong Yan et al.
Shiliang Wei et al.
Chitinase-3-like protein 1 (CHI3L1) is overexpressed in various types of diseases, particularly in sepsis, and contributes to disease progression. However, the role of CHI3L1 and the pathways involved in the progression of sepsis are not ye...
Interleukin 33 regulates the autophagy of oxygen-glucose-deprivation/reoxygenation microglia via macrophage polarization [0.03%]
白细胞介素33通过巨噬细胞极化调节氧-葡萄糖剥夺/复氧诱导的小胶质细胞自噬
Fan Yong,Lin Lili,Huang Kailiang et al.
Fan Yong et al.
Introduction: Interleukin (IL)-33 is a pleiotropic cytokine in the immune system and inflammatory responses, which is involved in cerebral ischemia/reperfusion (I/R) injury. Evidence indicates that IL-33 plays an essentia...
A rare case of sporotrichosis in a patient with late latent syphilis and diabetes mellitus: immunological aspects of sporotrichosis [0.03%]
一期梅毒和糖尿病患者身患孢子丝菌病的罕见病例报告：孢子丝菌病的免疫学特征
Natalia A Welc,Aleksandra Anioła,Sandra Ważniewicz et al.
Natalia A Welc et al.
Sporotrichosis, caused by Sporothrix schenckii, typically infects humans through skin trauma, leading to nodules or ulcers that complicate diagnosis. Rare forms, such as disseminated cutaneous sporotrichosis, occur more often in immunosuppr...
Mingwei Lv,Yirui Wang,Juan Du et al.
Mingwei Lv et al.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease influenced by environmental factors. Double-stranded DNA (dsDNA) serves as an antigen in various autoimmune diseases and is affected by meteorologica...
Lymphocyte variant hypereosinophilic syndrome with severe eosinophilic pneumonia treated with mepolizumab: a case report [0.03%]
利姆病变高嗜酸性综合症伴严重嗜酸细胞性肺炎采用美泊利单抗治疗的病例报告
Yubin Wang,Yuhan Tao,Hui Mao
Yubin Wang
Lymphocyte variant hypereosinophilic syndrome (L-HES) is a rare disorder characterized by immunophenotypically abnormal T lymphocytes that produce excessive eosinophilopoietic cytokines, such as interleukin 5 (IL-5). Clinically, patients wi...