Abnormally short activated partial thromboplastin times are related to elevated plasma levels of TAT, F1+2, D-dimer and FVIII:C [0.03%]
APTT缩短与血浆中TAT、F1+2、D-二聚体和FVIII:C水平升高有关
Edwin Ten Boekel,Piet Bartels
Edwin Ten Boekel
Abnormally short activated partial thromboplastin times (APTTs) are associated with an increased risk of thrombotic disorders. We have examined the status of coagulation activity in subjects with short APTTs. In addition, the presence of th...
Low molecular weight heparin for the prevention of deep venous thrombosis: a suitable monitoring in elderly patients? [0.03%]
低分子肝素预防深静脉血栓形成:老年人群是否适合监测?
Isabelle Mahé,Ludovic Drouet,Oliver Chassany et al.
Isabelle Mahé et al.
Monitoring of anti-Xa activity (aXa) levels is not routinely required in patients receiving enoxaparine at prophylactic dosages, since aXa is supposed to stay below the manufacturer's recommended range in patients treated for venous thrombo...
Prospective assessment of a nomogram for the initiation of oral anticoagulation therapy for outpatient treatment of venous thromboembolism [0.03%]
前瞻性评估启动口服抗凝治疗的列线图对门诊静脉血栓栓塞患者的疗效
M J Kovacs,D A Anderson,P S Wells
M J Kovacs
Venous thromboembolism is a common medical problem. Recently, the emphasis has been on a switch to outpatient low molecular weight heparin therapy. Previous warfarin nomograms have been developed only for inpatients. We prospectively assess...
Hemostasis and fibrinolysis factors in first-degree relatives of patients with Type 2 diabetes without hypertension [0.03%]
无高血压的2型糖尿病患者一级亲属血凝与纤维蛋白溶解因子的研究
A Trifiletti,A Lasco,R Scamardi et al.
A Trifiletti et al.
First-degree relatives of type 2 diabetic patients with or without a family history of hypertension are at increased risk for cardiovascular diseases. The aim of this study was to verify some possible hemostatic alterations in first-degree ...
Effect of an ionic compared to a non-ionic X-ray contrast agent on platelets and coagulation during diagnostic cardiac catheterisation [0.03%]
一种离子与非离子X线对比剂对诊断性心脏导管插入术中血小板及凝血的作用比较
F Jung,S G Spitzer,G Pindur
F Jung
The aim of the present study was to evaluate the effects of ionic (ioxaglate) and non-ionic (iopromide) contrast media on haemostatic parameters ex vivo. In 40 patients undergoing coronary angiography, platelet function (platelet reactivity...
Thromboplastin Bilbao: reproducibility and sensitivity of a Spanish thromboplastin [0.03%]
毕尔包凝血酶原激酶:西班牙产的敏感性和再现性
M Vacas,M J Aguirrebeitia,P J Lafuente et al.
M Vacas et al.
Prothrombin time (PT) is the control test for oral anticoagulant therapy as well as the screening test for defects of the extrinsic pathway of coagulation. Its responsiveness to decreased extrinsic clotting factors depends on the source and...
Treatment with vitamin K antagonists: frequency of indications and appropriateness of continuation [0.03%]
维生素K拮抗剂的治疗:指征使用频率及继续用药的适宜性分析
J F van Der Heijden,M G H Remkes,H R Büller et al.
J F van Der Heijden et al.
To prevent venous and arterial thrombosis vitamin K antagonists (VKA) are the treatment of choice for many indications. It is important to balance the benefits and the potential hazards of this treatment. An effective way to prevent unneces...
Majdi M Abdel-Raheem,Anil Potti,Sherine Tadros et al.
Majdi M Abdel-Raheem et al.
Background: Low-molecular-weight heparins (LMWHs) are being preferred to unfractionated heparin (UFH) because of their superior convenience and a comparable or slightly better toxicity profile. Whether LMWH has an inhibit...
Self-management of oral anticoagulants with a whole blood prothrombin-time monitor in elderly patients with atrial fibrillation [0.03%]
利用PT测定的自我管理口服抗凝剂在老年房颤患者中的应用
Amiram Eldor,Joseph Schwartz
Amiram Eldor
The efficacy of oral anticoagulants (OAC) in reducing the incidence of stroke in elderly patients with atrial fibrillation (AF) has been well documented. The intensity of OAC therapy and deviations in the prothrombin time (PT) are the stron...
Isolation of endogenous anticoagulant N-sulfated glycosaminoglycans in human plasma from healthy subjects [0.03%]
人血浆内源性抗凝糖胺聚糖的分离纯化
Marco Ruggiero,Michele Melli,Bruna Parma et al.
Marco Ruggiero et al.
Endogenous N-sulfated glycosaminoglycans (GAGs) comigrating with standard heparin and sensitive to nitrous acid treatment were isolated from plasma of healthy donors. The amount of these compounds was 7-10 microg/ml, and activated partial t...