Mutations and polymorphisms in genes affecting haemostasis components in children with thromboembolic events [0.03%]
与儿童血栓事件相关的止血成分基因的突变和多态性分析
A Komitopoulou,H Platokouki,Z Kapsimali et al.
A Komitopoulou et al.
The distribution of mutations/polymorphisms in genes affecting haemostasis [factor V Leiden (FVL), FV H1298R (FVR(2)), FII 20210A, b-Fib 455G-->A, FXIII V34L, PAI-1 4G, HPA-1b] among 141 children with thrombosis at various sites and 103 con...
Relationship between hemostatic factors and the platelet index in patients with ischemic heart disease [0.03%]
缺血性心脏病患者出血因素与血小板指数关系分析
Akihiro Ihara,Toshiharu Kawamoto,Kengo Matsumoto et al.
Akihiro Ihara et al.
To understand the heterogeneity of platelets, we investigated the correlation between hemostatic factors and the platelet index [platelet count, mean platelet volume (MPV), platelet-large cell ratio (P-LCR) and platelet distribution width (...
Mechanism of the antithrombotic effect of dietary diacylglycerol in atherogenic mice [0.03%]
饮食二酰基甘油抗血栓作用的机制研究(动脉粥样化小鼠模型)
Yoshinobu Ijiri,Aki Naemura,Tsutomu Yamashita et al.
Yoshinobu Ijiri et al.
Introduction: We have shown earlier that diacylglycerol (DAG) but not triacylglycerol (TAG) inhibited thrombus formation. The aim of the present study was to investigate the mechanism of this antithrombotic effect of DAG....
Relationship between platelet indexes and coronary angiographic findings in patients with ischemic heart disease [0.03%]
血小板指标与缺血性心脏病冠脉造影结果的关系研究
Akihiro Ihara,Toshiharu Kawamoto,Kengo Matsumoto et al.
Akihiro Ihara et al.
To understand the mechanisms linking platelets to the risk of coronary artery disease, we investigated the relation between coronary angiographic morphology and platelet indexes--platelet count, mean platelet volume (MPV), platelet-large ce...
Functional analysis of the factor IX epidermal growth factor-like domain mutation Ile66Thr associated with mild hemophilia B [0.03%]
因子IX表皮生长因子样结构域突变Ile66Thr与轻型乙型血友病的关系及其功能分析
Karin E Knobe,Kristina E M Persson,Elsy Sjörin et al.
Karin E Knobe et al.
The present study focused on the functional role of the mutation Ile66Thr located in the N-terminal epidermal growth factor-like domain of coagulation factor IX (FIX). This mutation causes mild hemophilia B with approximately 25% FIX coagul...
Effects of external electrical stimulation on laser-beam-induced experimental thrombosis [0.03%]
外部电刺激对激光束诱导实验性血栓形成的影响
O Aguejouf,F Doutremepuich,C Doutremepuich
O Aguejouf
External electrical stimulation (EES) has demonstrated venous antithrombotic properties. The aim of this investigation was to study its antithrombotic properties using unfractionated heparin (UFH) as a reference in arterial and venous mesen...
Modifications produced by indomethacin and L-NAME in the effect of ultralow-dose aspirin on platelet activity in portal hypertension [0.03%]
吲哚美辛和L-NAME对小剂量阿司匹林抑制门脉高压症血小板活化的影响及其机制研究
Francisco X Eizayaga,Omar Aguejouf,Vanessa Desplat et al.
Francisco X Eizayaga et al.
In our previous study, we demonstrated the effect of ultralow-dose aspirin (ULDA) on platelet activity and bleeding in rats with portal hypertension (PHT) produced by portal vein ligation (PVL). This paper reports modifications in this effe...
Patrizia Ferroni,Stefania Basili,Francesca Santilli et al.
Patrizia Ferroni et al.
Elevated low-density lipoprotein (LDL) cholesterol (LDL-C) levels represent one of the most important risk factors for atherosclerosis and therefore cardiovascular morbidity and mortality. LDL-C operates at different levels and through vari...
Modified low-density lipoproteins and high-density lipoproteins. From investigation tools to real in vivo players [0.03%]
改良的低密度脂蛋白和高密度脂蛋白。从研究工具到真正的体内参与者
Elisabeth Koller,Ivo Volf,Aner Gurvitz et al.
Elisabeth Koller et al.
It has long been known that the oxidative state of the various plasma lipoproteins modulates platelet aggregability, thereby contributing to atherogenesis. Low-density lipoprotein (LDL), occurring in vivo both in the native and oxidised for...