Pharmacogenomics with red cells: a model to study protein variants of drug transporter genes [0.03%]
使用红细胞进行药物基因组学研究：一种用于研究药物转运蛋白基因变异的模型
Willy Albert Flegel,Kshitij Srivastava,Tristan Michael Sissung et al.
Willy Albert Flegel et al.
The PharmacoScan pharmacogenomics platform screens for variation in genes that affect drug absorption, distribution, metabolism, elimination, immune adverse reactions and targets. Among the 1,191 genes tested on the platform, 12 genes are e...
10-year analysis of human immunodeficiency virus incidence in first-time and repeat donors in Brazil [0.03%]
巴西初次和重复献血者人类免疫缺陷病毒发病率的十年分析
Sheila de Oliveira Garcia Mateos,Liliana Preiss,Thelma T Gonçalez et al.
Sheila de Oliveira Garcia Mateos et al.
Background and objectives: Incidence in first-time and repeat blood donors is an important measure of transfusion-transmitted HIV infection (TT-HIV) risk. This study assessed HIV incidence over time at four large blood ce...
Blood supply sufficiency and safety management in Iran during the COVID-19 outbreak [0.03%]
COVID-19疫情期间伊朗的血液供应充足与安全管理
Mahtab Maghsudlu,Peyman Eshghi,Sedigheh Amini Kafi-Abad et al.
Mahtab Maghsudlu et al.
Background: COVID-19 first appeared in Iran on 19 February 2020, and then spread rapidly over the country. In this article, we review the action plan of the Iranian Blood Transfusion Organization with respect to this dise...
Development of an updated assay for prekallikrein activator in albumin and immunoglobulin therapeutics [0.03%]
在白蛋白和免疫球蛋白治疗药物中更新介导前激肽释放酶活化的检测方法的发展
Graham Roberts,Bernard Fox,Colin Longstaff
Graham Roberts
Background: Prekallikrein activator (PKA) is a contaminating enzyme found in therapeutic albumin and immunoglobulin products. The level is commonly measured using methods such as that defined by the European Pharmacopoeia...
In vitro diagnostics for screening the blood supply: the new European regulation for IVD and the WHO IVD prequalification programme [0.03%]
体外诊断筛查血液供应：欧洲体外诊断新法规和世界卫生组织的体外诊断预认证项目
Herbert Afegenwi Mbunkah,Jens Reinhardt,Chancelar Kafere et al.
Herbert Afegenwi Mbunkah et al.
Blood transfusion remains a routine life-saving medical procedure that helps replace blood lost due to surgery, injury or disease. The quality of transfused blood is crucial in this process as blood donors must be free of transfusion-transm...
Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors [0.03%]
干细胞采集流程图的开发与评估，以支持教育和招募承诺的干细胞捐赠者
Warren Fingrut,Ari B Cuperfain,Sze Wah Samuel Chan et al.
Warren Fingrut et al.
Background: Diagrams which allow potential unrelated stem cell donors to visualize the stem cell collection process were hypothesized to support the recruitment and education of committed stem cell donors. ...
Gone, but haven't forgotten: insights on plasmapheresis donation from lapsed donors [0.03%]
消失但未被遗忘：来自停止捐赠者的血浆pheresis捐赠见解
Rachel Thorpe,Lilly Nguyen,Barbara M Masser et al.
Rachel Thorpe et al.
Background and objectives: Blood Collection Agencies in several countries have implemented strategies to increase the number of plasmapheresis collections. Despite this, a sizable minority of plasma donors lapse from dona...
Whole blood haemostatic function throughout a 28-day cold storage period: an in vitro study [0.03%]
冷储存28天全血凝固功能的变化：一项体外研究
Hannah L McRae,Ferhat Kara,Chelsea Milito et al.
Hannah L McRae et al.
Background: In recent years, there has been renewed interest in whole blood (WB) transfusion, particularly in damage control resuscitation, in part due to the ability to provide the adequate ratio of blood components in a...
Cryopreserved platelets and their suitability in being re-suspended in additive solution [0.03%]
冷冻血小板及其能否悬浮于添加剂溶液中的适用性研究
Colin McLean,Loraine McMillan,Juraj Petrik et al.
Colin McLean et al.
Background: Cryopreserved platelets are generally produced and stored in plasma. With the advent of additive solutions being routinely used it would be prudent to examine producing and storing these units in a platelet ad...
Severe acute respiratory syndrome coronavirus-2: implications for blood safety and sufficiency [0.03%]
严重急性呼吸综合征冠状病毒2对血液安全性和充足性的意义
Philip Kiely,Veronica C Hoad,Clive R Seed et al.
Philip Kiely et al.
Background and objective: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus, first identified in China at the end of 2019 and has now caused a worldwide pandemic. In this review, we provi...