Role of HER2-Related Biomarkers (HER2, p95HER2, HER3, PTEN, and PIK3CA) in the Efficacy of Lapatinib plus Capecitabine in HER2-Positive Advanced Breast Cancer Refractory to Trastuzumab [0.03%]
赫赛汀耐药性 HER2 阳性晚期乳腺癌患者来那替尼联合卡培他滨治疗疗效的 HER2 相关生物标志物(P95HER2、HER3、PTEN 和 PIK3CA)作用研究
Reiki Nishimura,Uhi Toh,Maki Tanaka et al.
Reiki Nishimura et al.
Objective: The aim of this study was to investigate the correlation between human epidermal growth factor receptor 2 (HER2)-related biomarkers and the treatment outcomes using lapatinib plus capecitabine (LC) and to evalu...
Evaluation of the Effectiveness of a Multimodal Complementary Medicine Program for Improving the Quality of Life of Cancer Patients during Adjuvant Radiotherapy and/or Chemotherapy or Outpatient Aftercare [0.03%]
综合癌症姑息治疗对改善肿瘤患者放化疗及门诊随访期间生活质量的效果评价研究
Martin Domnick,Manju Domnick,Karl-Rüdiger Wiebelitz et al.
Martin Domnick et al.
Objectives: Evidence for complementary therapies as important strategies to relieve cancer treatment-associated symptoms is increasing. Mostly, these complementary therapies start at the end of adjuvant treatments, result...
Randomized Controlled Trial
Oncology. 2017;93(2):83-91. DOI:10.1159/000468939 2017
Prognostic Parameters for Patients with Cervical Cancer FIGO Stages IA2-IIB: A Long-Term Follow-Up [0.03%]
FIGO IA2-IIB期宫颈癌患者的预后因素：长期随访研究
Bogdan Obrzut,Andrzej Semczuk,Maciej Naróg et al.
Bogdan Obrzut et al.
Objective: We assessed the prognostic factors related to 10-year overall survival and disease-free survival in cervical cancer patients that underwent primary surgical protocols in 1 institution. ...
Taurolidine/Citrate Lock Therapy for Primary Prevention of Catheter-Related Infections in Cancer Patients: Results of a Prospective, Randomized, Phase IV Trial (ATAPAC) [0.03%]
依坦立定/枸橼酸封管溶液用于预防癌症患者隧道式带隧道涤纶套中心静脉导管相关感染的随机、前瞻性、IV期临床试验（ATAPAC研究）
Raffaele Longo,Mathieu Llorens,Christophe Goetz et al.
Raffaele Longo et al.
Background: Totally implantable venous access port (TIVAP)-related infections (RIs) remain a serious health problem in cancer patients receiving an intravenous (i.v.) therapy. ...
Clinical Trial
Oncology. 2017;93(2):99-105. DOI:10.1159/000470911 2017
Outcome of All-Oral Direct-Acting Antiviral Regimens on the Rate of Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Genotype 1-Related Chronic Liver Disease [0.03%]
直接抗病毒方案对丙型肝炎病毒感染的相关慢性肝病患者肝细胞癌发生率的影响：一项回顾性研究
Fumihiro Ogata,Masahiro Kobayashi,Norio Akuta et al.
Fumihiro Ogata et al.
Objectives: There is little information on the risk factors for hepatocellular carcinoma (HCC) and outcome of treatment with an all-oral combination of direct-acting antiviral regimens following eradication of hepatitis C...
Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma [0.03%]
肝内胆管癌中Hippo信号通路分子表达的改变
Keishi Sugimachi,Miki Nishio,Shinichi Aishima et al.
Keishi Sugimachi et al.
Objective: MOB1, a core component of the Hippo signaling pathway, suppresses cell proliferation, and MOB1 liver conditional knockout mice develop intrahepatic cholangiocarcinoma (ICC). However, its clinical significance i...
Feasibility of Modified FOLFOX in Elderly Patients Aged ≥80 Years with Metastatic Gastric Cancer or Colorectal Cancer [0.03%]
改良FOLFOX方案治疗≥80岁老年转移性胃癌或结直肠癌患者的可行性研究
Kyu-Hyoung Lim,Hui-Young Lee,Sung Bae Park et al.
Kyu-Hyoung Lim et al.
Objective: The aim of this study was to assess the feasibility of a modified FOLFOX regimen as first-line treatment in elderly patients with metastatic gastric cancer (GC) or colorectal cancer (CRC). ...
Clinical Trial
Oncology. 2017;93(2):115-121. DOI:10.1159/000471767 2017
Cetuximab-Carboplatin-5-Fluorouracil Regimen in Elderly Patients with Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma: A French Retrospective Survey [0.03%]
老年复发或转移性头颈部鳞癌患者接受西妥昔单抗联合卡铂和氟尿嘧啶新辅助治疗的疗效观察：一项法国回顾性调查研究
Mickaël Burgy,Philippe Barthélémy,François Lefevre et al.
Mickaël Burgy et al.
Background: The cetuximab plus platinum-based chemotherapy regimen is a standard of care in the treatment of recurrent or metastatic head and neck squamous-cell carcinoma (HNSCC). The feasibility in the elderly population...
Risk and Survival of Patients with Head and Neck Cutaneous Melanoma: National Perspective [0.03%]
美国头颈部黑色素瘤患者的危险因素及生存率分析：全国范围的角度
Zaid Al-Qurayshi,Mohamed Hassan,Sudesh Srivastav et al.
Zaid Al-Qurayshi et al.
Objective: Head and neck cutaneous melanoma represents a distinct entity of skin cancer. We aim to examine management and survival of patients with head and neck cutaneous melanoma. ...
Prolactin as a Potential Early Predictive Factor in Metastatic Non-Small Cell Lung Cancer Patients Treated with Nivolumab [0.03%]
作为尼伏单抗治疗的转移性非小细胞肺癌患者的潜在早期预测因子的优点
Salvatore Caponnetto,Giovanni Maria Iannantuono,Giacomo Barchiesi et al.
Salvatore Caponnetto et al.
Background/aims: Prolactin (PRL) is a peptide hormone and several studies have demonstrated its role as a cytokine in human T cell-mediated immunity. We are unaware if PRL is a positive or negative immunomodulator, but it...
Observational Study
Oncology. 2017;93(1):62-66. DOI:10.1159/000464328 2017