Long-Term Survival Outcomes in Locally Advanced Breast Cancer after Mastectomy with or without Breast Reconstruction [0.03%]
保乳术与乳房重建对局部晚期乳腺癌长期生存结局的影响
Heng Zhang,AiJie Zhang,Tingting Wei et al.
Heng Zhang et al.
Introduction: There is ongoing debate about the safety of breast reconstruction for patients with locally advanced breast cancer (LABC) who have undergone total mastectomy (TM). More and more LABC patients are undergoing ...
Tissue and Imaging Biomarkers of Response to Neoadjuvant Nivolumab or Nivolumab plus Ipilimumab in Patients with Resectable Hepatocellular Carcinoma [0.03%]
可切除肝细胞癌患者新辅助纳武单抗或纳武单抗联合伊匹木单抗治疗的组织和影像生物标志物响应性研究
Michael LaPelusa,Shadi Chamseddine,Hop Sanderson Tran Cao et al.
Michael LaPelusa et al.
Introduction: Perioperative immunotherapy has shown promise in some patients with early-stage hepatocellular carcinoma (HCC). This study examined tissue and imaging biomarkers associated with pathologic response in a phas...
Poor Tolerability of Lenvatinib in Elderly Patients with Advanced Hepatocellular Carcinoma after Disease Progression following First-Line Atezolizumab Plus Bevacizumab: A Multicenter Study [0.03%]
一项多中心研究：接受阿特珠单抗联合贝伐珠单抗一线治疗后疾病进展的老年晚期肝细胞癌患者对仑伐替尼耐受性较差
Daisuke Kato,Takanori Suzuki,Kentaro Matsuura et al.
Daisuke Kato et al.
Introduction: We investigated the effectiveness of lenvatinib (LEN) after disease progression following first-line treatment with atezolizumab plus bevacizumab (Atez/Bev) in patients with unresectable hepatocellular carci...
Real-World Analysis of the Correlation between Overall Survival and Progression-Free Survival in Advanced Pancreatic Cancer: Results of NAPOLEON-1 and 2 Studies [0.03%]
基于NAPOLEON-1和2研究的晚期胰腺癌患者总生存与无进展生存相关性的真实世界分析
Tomonori Araki,Machiko Kawahira,Mototsugu Shimokawa et al.
Tomonori Araki et al.
Introduction: Fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) improve overall survival (OS) and progression-free survival (PFS) in patients with pancreatic cancer, compared with gemcitabine (GEM). Howev...
Identification of Immune-Related Gene Signature Model for Predicting Lung Cancer Survival and Response to Immunotherapy [0.03%]
用于预测肺癌生存率和免疫治疗反应的免疫相关基因特征模型的鉴定
Wenrong Lin,XiaoJun Cai,YiJin Lin et al.
Wenrong Lin et al.
Introduction: Studies have shown that immune-related genes play a crucial role in tumor development and treatment. However, the specific roles and potential value of these genes in lung cancer patients are still not fully...
MUC17 is a potential new prognostic biomarker and promotes pancreatic cancer progression in obstructive jaundice [0.03%]
MUC17是一个新的预后生物标志物并能在阻塞性黄疸中促进胰腺癌发展
Eleonóra Gál,István Menyhárt,Zoltán Veréb et al.
Eleonóra Gál et al.
Our working group has previously shown that bile acids (BAs) accelerate carcinogenic processes in pancreatic cancer (PC) in which mucin 4 (MUC4) expression has a central role. However, the role of other mucins in PC are less clear, especial...
Lenvatinib versus Sorafenib Second-Line Therapy in Patients with Hepatocellular Carcinoma Progressed to Atezolizumab plus Bevacizumab: A Retrospective Real-World Study [0.03%]
仑伐替尼与索拉非尼二线治疗阿特珠单抗联合贝伐珠单抗进展的肝细胞癌患者：一项真实世界回顾性研究
Mara Persano,Andrea Casadei-Gardini,Toshifumi Tada et al.
Mara Persano et al.
Introduction: The most frequently used first-line treatment in patients with advanced hepatocellular carcinoma (HCC) is atezolizumab plus bevacizumab. Upon progression after this treatment, the standard of care in many co...
Rene Novysedlak,Miray Guney,Majd Al Khouri et al.
Rene Novysedlak et al.
Background: Prostate cancer (PCa) is a malignancy with significant immunosuppressive properties and limited immune activation. This immunosuppression is linked to reduced cytotoxic T cell activity, impaired antigen presen...
Review
Oncology. 2024 Oct 9:1-25. DOI:10.1159/000541881 2024
Efficacy and Safety of Autologous Stem Cell Transplantation in First-Line Treatment and at Relapse in Elderly Patients with Multiple Myeloma [0.03%]
自体干细胞移植在多发性骨髓瘤老年患者初治及复发时的有效性和安全性
Eva-Maria Klein,Sejla Hujic,Kaya Miah et al.
Eva-Maria Klein et al.
Introduction: Although recent data suggest that melphalan high-dose therapy followed by autologous stem cell transplantation (HDT/ASCT) is safe and effective in eligible multiple myeloma (MM) patients up to the age of 75 ...
Lobectomy with Lymph Node Dissection Benefits N3 Stage Non-Small Cell Lung Cancer Patients: A Population-Based Study [0.03%]
肺癌N3期非小细胞患者的肺叶切除加淋巴结清扫手术的疗效研究：基于人口的队列研究
Zhoujunyi Tian,Jin Zhang,Deruo Liu et al.
Zhoujunyi Tian et al.
Introduction: There remain controversies about the role of surgery for N3 stage non-small cell lung cancer (NSCLC) patients. Methods: N...