Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer Patients Progressing after Docetaxel: A Prospective Single-Center Study [0.03%]
卡巴他赛治疗多西他赛治疗后进展的转移性去势抵抗性前列腺癌患者：一项前瞻性单中心研究
Giuseppe Cicero,Rossella De Luca,Patrizia Dorangricchia et al.
Giuseppe Cicero et al.
Purpose: The present study aims to evaluate the efficacy of cabazitaxel in combination with prednisone treatment in Italian patients affected by hormone-refractory metastatic castration-resistant prostate cancer (mCRPC) p...
Lean Body Weight and Metformin Are Insufficient to Prevent Endometrial Hyperplasia in Mice Harboring Inactivating Mutations in PTEN [0.03%]
lean body weight 和 metformin 不足以预防 PTEN 失活突变小鼠的子宫内膜增生
David A Iglesias,Qian Zhang,Joseph Celestino et al.
David A Iglesias et al.
Objectives: Obesity is a major risk factor for endometrial cancer. We evaluated whether obesity exacerbates progression of endometrial hyperplasia (EH) using the PRCre/+ PTENflox/+ mouse model and examined if the type 2 d...
Why Should Phase 1 Cancer Trial Participation and Optimal End-of-Life Care Be Incompatible? [0.03%]
为什么I期临床试验和最佳的临终关怀之间是相互排斥的？
Maurie Markman
Maurie Markman
Clinicopathological Features and Predictive Factors for Colorectal Cancer Outcome in the Kingdom of Saudi Arabia [0.03%]
沙特阿拉伯结直肠癌的临床病理特征及预后因素分析
Abdurrahman Aldiab,Khayal A Al Khayal,Omar A Al Obaid et al.
Abdurrahman Aldiab et al.
Background/aims: Colorectal cancer (CRC) is the most frequent cancer and a leading cause of cancer death in the Kingdom of Saudi Arabia (KSA). To date, no nationwide screening programs have been adopted. This prospective,...
Feasibility of Preoperative Chemotherapy with Docetaxel, Cisplatin, and 5-Fluorouracil versus Adriamycin, Cisplatin, and 5-Fluorouracil for Resectable Advanced Esophageal Cancer [0.03%]
术前化疗采用多西紫杉醇、顺铂和氟尿嘧啶与阿霉素、顺铂和氟尿嘧啶治疗可手术的晚期食管癌的可能性：II期临床试验结果
Osamu Shiraishi,Makoto Yamasaki,Tomoki Makino et al.
Osamu Shiraishi et al.
Background: Neoadjuvant chemotherapy for resectable advanced esophageal squamous cell carcinoma (ESCC) requires reassessment. We have conducted a trial aiming at the comparison between DCF and ACF concerning perioperative...
The Presence of HPV DNA in Neck Lymph Node Metastasis Correlates with Improved Overall Survival of Patients with Oropharyngeal Cancer Undergoing Surgical Treatment [0.03%]
人乳头瘤病毒DNA存在于颈部淋巴结转移灶与经手术治疗的咽癌患者总体生存率提高有关
Eiji Shimura,Takanori Hama,Toshihito Suda et al.
Eiji Shimura et al.
Background: Few studies have addressed how human papilloma virus (HPV) infection in oropharyngeal squamous cell carcinoma (OPSCC) affects the outcome of surgical therapy; furthermore, the relationship between the presence...
Dosimetric Improvements with a Novel Breast Stereotactic Radiotherapy Device for Delivery of Preoperative Partial-Breast Irradiation [0.03%]
用于术前部分乳腺照射的新型乳房立体定向放射治疗装置的剂量学改进
James W Snider,Yildirim Mutaf,Elizabeth Nichols et al.
James W Snider et al.
Objective: Partial-breast irradiation (PBI) with external-beam radiotherapy has produced higher than expected rates of fair-to-poor cosmesis. Worsened outcomes have been correlated with larger volumes of breast tissue exp...
Clinical Trial
Oncology. 2017;92(1):21-30. DOI:10.1159/000449388 2017
The Expression of CCAT2, a Novel Long Noncoding RNA Transcript, and rs6983267 Single-Nucleotide Polymorphism Genotypes in Colorectal Cancers [0.03%]
结肠直肠癌中长链非编码RNA CCAT2表达及其基因多态性研究
Yuta Kasagi,Eiji Oki,Koji Ando et al.
Yuta Kasagi et al.
Colon cancer-associated transcription 2 (CCAT2) was recently identified as a novel long noncoding RNA transcript encompassing the single-nucleotide polymorphism rs6983267. CCAT2 is overexpressed in colorectal cancer (CRC) where it promotes ...
Five Years of Multidisciplinary Care in Hereditary Cancer: Our Experience in a Spanish University Hospital [0.03%]
我们所在西班牙大学医院遗传性肿瘤多学科综合治疗的五年经验
I Márquez-Rodas,M Lobo,C Flores-Sanchez et al.
I Márquez-Rodas et al.
Objective: To analyse the evolution of a multidisciplinary heredofamilial cancer unit (HFCU) in a university hospital. Methods: This wa...
Targeted Therapies Provide Treatment Options for Poorly Differentiated Pancreatic Neuroendocrine Carcinomas [0.03%]
针对分化不良的胰腺神经内分泌癌的治疗选项：靶向疗法
Marine Gilabert,Young Soo Rho,Petr Kavan
Marine Gilabert
Poorly differentiated pancreatic neuroendocrine carcinoma (PD pNECs) is a rare disease that has a poor prognosis and is treated with systemic chemotherapy as the standard of care. We present 6 cases of chemo-naïve patients diagnosed with P...