Nitric Oxide/Glucose Transporter Type 4 Pathway Mediates Cardioprotection against Ischemia/Reperfusion Injury under Hyperglycemic and Diabetic Conditions in Rats [0.03%]
一氧化氮/葡萄糖转运蛋白4信号通路介导了大鼠高血糖和糖尿病条件下心肌缺血再灌注损伤的保护作用
Aisha Al-Kouh,Fawzi Babiker
Aisha Al-Kouh
Introduction: The comorbidities of ischemic heart disease (IHD) and diabetes mellitus (DM) compromise the protection of the diabetic heart from ischemia/reperfusion (I/R) injury. We hypothesized that manipulation of reper...
RNA Sequencing Screens the Key Genes and Pathways in a Mouse Model of HFpEF [0.03%]
RNA测序筛选HFpEF小鼠模型中的关键基因和通路
Yuxi Sun,Jiaxin Li,Xinxin Zhang et al.
Yuxi Sun et al.
Introduction: Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high morbidity and mortality but without available evidence-based therapies. It is essential to investigate changes in gene ex...
Cytoprotection as an Innovative Therapeutic Strategy to Cardiogenic Shock: Exploring the Potential of Cytidine-5-Diphosphocholine to Mitigate Target Organ Damage [0.03%]
细胞保护作为心源性休克的创新治疗策略：探索胞苷二磷酸胆碱减轻靶器官损害的潜力
Héctor González-Pacheco,Luis Manuel Amezcua-Guerra,Martha Franco et al.
Héctor González-Pacheco et al.
Background: Preservation of organ function and viability is a crucial factor for survival in cardiogenic shock (CS) patients. There is not information enough on cytoprotective substances that may delay organs damage in CS...
Laser Doppler Fluximetry in Cutaneous Vasculature: Methods for Data Analyses [0.03%]
激光多普勒血流量测定法在皮肤血管中的应用：数据分析方法
Sophie J Y Huang,Xuan Wang,Brayden D Halvorson et al.
Sophie J Y Huang et al.
Introduction: Acquisition of a deeper understanding of microvascular function across physiological and pathological conditions can be complicated by poor accessibility of the vascular networks and the necessary sophistica...
The Incidence of Pulmonary Embolism in Hospitalized Non-ICU Patients with COVID-19 during the First Wave: A Multicenter Retrospective Cohort Study in the Netherlands [0.03%]
荷兰第一波疫情期间非ICU住院COVID-19患者的肺栓塞发生率：一项多中心回顾性队列研究
Arno F G Maas,Caroline Wyers,Arne Dielis et al.
Arno F G Maas et al.
Introduction: During the first COVID-19 outbreak in 2020 in the Netherlands, the incidence of pulmonary embolism (PE) appeared to be high in COVID-19 patients admitted to the intensive care unit (ICU). This study was perf...
Multicenter Study
Journal of vascular research. 2024;61(3):142-150. DOI:10.1159/000538312 2024
Steven K Malin,Uta Erdbrügger
Steven K Malin
Background: Insulin resistance is a major etiological factor in obesity, type 2 diabetes, and cardiovascular disease (CVD). Endothelial dysfunction may precede impairments in insulin-stimulated glucose uptake, thereby mak...
Uncoupling Protein 2 Alleviates Myocardial Ischemia/Reperfusion Injury by Inhibiting Cardiomyocyte Ferroptosis [0.03%]
解偶联蛋白2通过抑制心肌细胞铁死亡减轻心肌缺血再灌注损伤
Peiting Zhou,Yaolei Zhang,Kewei Xu et al.
Peiting Zhou et al.
Introduction: Following our recent finding that Ucp2 knockout promotes ferroptosis, we aimed to examine whether UCP2 alleviates myocardial ischemia/reperfusion injury (MI/RI) by inhibiting ferroptosis. ...
Metabolic Syndrome and Cardiac Vessel Remodeling Associated with Vessel Rarefaction: A Possible Underlying Mechanism May Result from a Poor Angiogenic Response to Altered VEGF Signaling Pathways [0.03%]
代谢综合征与血管稀疏相关的心脏血管重塑：可能的潜在机制可能是血管生成反应较差导致VEGF信号通路改变所致
Krzysztof Bartkowiak,Mateusz Bartkowiak,Ewa Jankowska-Steifer et al.
Krzysztof Bartkowiak et al.
Background: Elevated mortality rates in patients with metabolic syndrome (MetS) are partly due to adverse remodeling of multiple organs, which may lead to cardiovascular disease, nonalcoholic fatty liver disease, kidney f...
Assessment for Carotid Atherosclerotic Plaque Using Vessel Wall Magnetic Resonance Imaging: A Multireader ROC Study to Determine Optimal Sequence for Detecting Vessel Wall Calcification [0.03%]
血管壁磁共振成像评估颈动脉斑块用于检测血管壁钙化：多阅片人ROC研究确定最佳序列
Hideki Ishimaru,Yohei Ikebe,Tsuyoshi Izumo et al.
Hideki Ishimaru et al.
Introduction: We aimed to compare conventional vessel wall MR imaging techniques and quantitative susceptibility mapping (QSM) to determine the optimal sequence for detecting carotid artery calcification. ...
Comparative Study
Journal of vascular research. 2024;61(3):122-128. DOI:10.1159/000538175 2024
Autophagy Induced by Low Shear Stress Leads to Endothelial Glycocalyx Disruption [0.03%]
低切应力诱导的自噬导致内皮糖萼破坏
Lina Lin,Wei Gao,Linya Feng et al.
Lina Lin et al.
Introduction: Previous studies have confirmed that low shear stress (LSS) induces glycocalyx disruption, leading to endothelial dysfunction. However, the role of autophagy in LSS-induced glycocalyx disruption and relevant...