Evidence in Favour of Calcium-Sensing Receptor(CaSR) in L-cysteine-mediated Vasorelaxation of Mouse Thoracic Aorta [0.03%]
L-半胱氨酸介导的鼠胸主动脉血管舒张作用中的钙感受器证据
Nuran Ogulener,Busra Akarsakarya,Fatma Aydinoglu
Nuran Ogulener
Introduction: In our study, the possible role of the calcium-sensing receptor (CaSR) pathway in L-cysteine/Hydrogen sulfide (H2S)-induced vasorelaxations was investigated in isolated mouse thoracic aorta tissue. ...
Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function [0.03%]
免疫抑制药物对内皮细胞功能具有不同的影响
Aly Elezaby,Ryan Dexheimer,David Wu et al.
Aly Elezaby et al.
Immunosuppressive medications are widely used to treat patients with neoplasms, autoimmune conditions, and solid organ transplants. Prior studies indicate that immunosuppression drugs can cause adverse vascular remodeling. Given the systemi...
Deficiency of p27kip1, a cyclin-dependent kinase inhibitor, accelerates topical elastase/3-aminopropionitrile fumarate salt-induced abdominal aortic aneurysm development in mice [0.03%]
p27kipl周期素依赖性激酶抑制剂缺乏可加速小鼠表皮弹性蛋白酶/3-氨基丙腈富马酸盐诱导的腹主动脉瘤形成
Keisuke Kamada,Hong Niu,Shinsuke Kikuchi et al.
Keisuke Kamada et al.
Introduction: Abdominal aortic aneurysm (AAA) is a multifactorial disease with limited identification of contributing genetic factors. p27kip, also known as CDKN1B, is a cell cycle inhibitor that regulates vascular smooth...
Investigating the role of growth differentiation factor-15 as a biomarker of inflammation in patients with atherosclerotic vascular disease [0.03%]
探讨生长分化因子-15在动脉粥样硬化性血管病炎症标志物中的作用
Joong Min Park,Ian Beckman,Kaye Beckman et al.
Joong Min Park et al.
Inflammatory pathways in vascular disease are the focus of intense interest. Accumulating evidence suggests a role for GDF-15 in the atherosclerotic process. In this study we measured circulating levels of IL-6 and GDF-15 in a cohort of 20 ...
Exploring potential causality and molecular mechanisms between heart failure and renal failure: insights from Mendelian randomization studies, the MIMIC-IV database and the GEO database [0.03%]
基于孟德尔随机化研究、MIMIC-IV数据库和GEO数据库探讨心力衰竭与肾衰竭的潜在因果关系及分子机制
Shaoyi Peng,Hailong Li,Kaiyuan Li
Shaoyi Peng
Background: Heart failure (HF) and renal failure (RF) frequently coexist as cardiorenal syndrome, but their underlying causal mechanisms remain poorly defined. ...
Vasomotion in Human Fingers [0.03%]
人体手指的血管运动
Pekka Talke,Jonathan S Maltz,Marcus Talke et al.
Pekka Talke et al.
Introduction: We describe methods by which vasomotion can be recorded in awake and anesthetized human subjects without significant interference from other spontaneous vascular oscillations. ...
A State-wide Retrospective Cohort Study Examining Effects of Transfusing Old Blood Products in Vascular Surgical Patients [0.03%]
输血对血管外科患者预后影响的队列研究：旧血液比新血液更危险吗？
Nchafatso Obonyo,Lawrence Lu,Zohaib Nadeem et al.
Nchafatso Obonyo et al.
Introduction We investigated the effects of transfusing blood products close to the expiration date (i.e., ≥35 days packed red blood cells (PRBCs) and >3 days platelets (PLTs)) on vascular patients. Methods We retrospectively examined all ...
Exposure to Artificial Light at Night Alters Ultradian Rhythms in Endothelial Function [0.03%]
夜间暴露在人造光下会改变血管内皮功能的超周期节律
James C Walton,O Hecmarie Meléndez-Fernández,A Courtney DeVries et al.
James C Walton et al.
Endogenous biological timing mechanisms are fundamental aspects of living cells, tissues, and organisms. Virtually every aspect of physiology and behavior is mediated by self-sustaining circadian clocks, which depend on light to synchronize...
A Novel Preclinical Model of Peripheral Artery Disease in Swine for Investigating Flow-Induced Angiogenesis [0.03%]
一种新的用于探究血流介导的新生血管形成的外周动脉疾病猪前临床模型
Grzegorz Jodlowski,May Dvir,Colin Price et al.
Grzegorz Jodlowski et al.
Introduction: Peripheral artery disease (PAD) affects over 200 million people globally and remains a therapeutic challenge, particularly in patients who are not candidates for standard revascularization. While shear stres...
Malha Sadoune,Jérome Mourad,Céline Luc et al.
Malha Sadoune et al.
Introduction: QSOX1, a sulfhydryl oxidase involved in arterial remodelling, has recently emerged as a biomarker for preeclampsia and acute heart failure. This study sought the cardiovascular roles of Qsox1 in response to ...