Vascular Ageing in Conditions Associated With Early Onset Hypogonadism [0.03%]
与青春期前性腺功能减退相关的条件下的血管衰老
Angela K Lucas-Herald,Jane D McNeilly,S Faisal Ahmed
Angela K Lucas-Herald
Introduction: Early-onset hypogonadism may increase the risk of early vascular ageing (EVA). Methods: Boys with conditions linked to in...
Mediastinal lymphadenopathy as a prognostic marker in acute pulmonary embolism [0.03%]
急性肺栓塞的纵隔淋巴结病作为预后标志物
Hans-Jonas Meyer,Mattes Hinnerichs,Anar Aghayev et al.
Hans-Jonas Meyer et al.
Introduction: Computed tomography (CT) is the modality of choice to diagnose acute pulmonary embolism (PE). The present multicentric study aimed to demonstrate the prognostic role of mediastinal lymphadenopathy for short ...
INHIBITION OF H₂S PRODUCTION REDUCES PORTAL PRESSURE AND ATTENUATES LIVER FIBROSIS IN BILE DUCT-LIGATED RATS [0.03%]
抑制H2S生成可降低胆管结扎大鼠门脉压并减轻肝纤维化程度
Raffaele Buono,Marika Crescenzi,Alessandra Brocca et al.
Raffaele Buono et al.
Hydrogen sulfide (H2S) is a gaseous signalling molecule with vasodilatory properties and regulates inflammation and fibrosis in the liver. Rats with bile duct ligation-induced liver disease were treated with propargylglycine (PAG; 30 mg/kg ...
Deletion of Murine Endothelial Bag3 Alters the Cellular Proteome Among Organs of Origin [0.03%]
删除内皮细胞Bag3影响器官来源细胞的蛋白质组学状态
Zoë S Terwilliger,Feifei Li,Ananya Pentakota et al.
Zoë S Terwilliger et al.
BAG3 (Bcl-2 associated athanogene 3) is a multifunctional protein with pleiotropic effects in multiple cell types. Despite our knowledge of its role in cardiovascular disease, its specific role in endothelial cells (ECs) is unknown. The pur...
Rohit S Nampoothiry,Nadra Salman,Ricardo Bernardino de Paula et al.
Rohit S Nampoothiry et al.
Background: Hypertension is a major risk factor for cardiovascular disease, yet its effects on the retinal microvasculature in women, independent of pregnancy and diabetes, remain poorly understood. ...
Expression of circulating miRNA before and after abdominal aneurysm repair [0.03%]
腹主动脉瘤手术前后循环中miRNA的表达
Xinji Tan,Daphne Elisabeth Gray,Kerstin Troidl et al.
Xinji Tan et al.
Introduction: Numerous studies have identified various miRNAs involved in aortic aneurysm pathology. This study investigates circulating miRNAs before and after abdominal aortic aneurysm repair (open surgical repair [OSR]...
Plasmin-PAI-1 Imbalance Contributes to Hyperglycemia-Induced Vascular Calcification [0.03%]
纤溶酶-PAI-1失衡参与高糖诱导的血管钙化
Yosuke Kanno,Moeko Okuno,Osamu Matsuo et al.
Yosuke Kanno et al.
Background: Vascular calcification (VC) is a frequent complication in diabetes and is linked to an increased risk of thrombotic cardiovascular events. Diabetes is characterized by impaired fibrinolysis, and accumulating e...
Rapid Quantitative Imaging of Heterogenous Tissue Hemoglobin Dynamics Using Spatial Frequency Domain Imaging [0.03%]
基于空间频率域成像的组织异质性血液动力学快速定量检测方法
Gordon T Kennedy,Rebecca Rowland,Amaan Mazhar et al.
Gordon T Kennedy et al.
Introduction: Arterial insufficiency is a key factor in chronic wounds, diabetes, and peripheral arterial disease, all of which impair vascular function. Accurate monitoring of tissue-level oxygenation and hemodynamics is...
Hydroxychloroquine administration mitigates atherosclerotic plaque progression in ApoE knockout mice by inhibiting neutrophil extracellular trap formation and autophagy [0.03%]
羟基氯喹通过抑制中性粒细胞胞外陷阱形成和自噬抑制ApoE基因敲除小鼠动脉粥样硬化斑块进展
Dimitrios Sagris,Anastasia-Maria Natsi,Konstantina Zacharouli et al.
Dimitrios Sagris et al.
Introduction: Hydroxychloroquine (HCQ) has been associated with lower incidence of cardiovascular events in patients with autoimmune diseases and atherosclerosis progression in mouse models. Our study aimed at investigati...
Methyl Palmitate, a potent Angiotensin Converting Enzyme inhibitor attenuates vascular remodelling in L-NG-Nitro Arginine Methyl Ester-induced hypertensive Wistar rat models [0.03%]
甲基棕榈酸盐通过抑制血管紧张素转换酶缓解L-NG-硝基-L-精氨酸甲酯诱导的高血压大鼠模型中的血管重构
Ashwini Rao,Padmanabha Udupa E G,Cheryl Rhea Lewis et al.
Ashwini Rao et al.
Introduction: Angiotensin Converting Enzyme (ACE) regulates blood pressure via the renin-angiotensin and bradykinin systems.Though synthetic ACE inhibitors are more effective, they pose several side effects.Methyl Palmita...