Nano-Sized Drug Delivery Systems: Development and Implication in Treatment of Hepatocellular Carcinoma [0.03%]
纳米载体药物输送系统用于肝细胞癌治疗的发展及其影响
Khan Farheen Badrealam,Mohammad Owais
Khan Farheen Badrealam
Liver cancer results in enormous human toll worldwide. Over the years, various chemotherapeutic entities have been employed for treatment of advanced HCC; however, as of yet none embody attributes to improve overall survival. Following rapi...
Sorafenib for Hepatocellular Carcinoma: From Randomized Controlled Trials to Clinical Practice [0.03%]
肝细胞癌的索拉非尼治疗：从随机临床试验看临床实践
Giuseppe Cabibbo,Salvatore Petta,Marcello Maida et al.
Giuseppe Cabibbo et al.
Hepatocellular carcinoma is a challenging malignancy of global importance. It is the sixth most common solid malignancy and the third leading cause of cancer-related death, worldwide. Curative treatments at early stages include liver transp...
Rodolfo Sacco,Luigi Giorgi,Lorenzo Fornaro et al.
Rodolfo Sacco et al.
This article offers an overview of a new therapeutic option in hepatocellular carcinoma using trans-arterial radioembolization. In particular, it covers practical aspects of the technique and the currently available preliminary data in term...
Yo-Ichi Yamashita,Ken Shirabe,Shinichi Aishima et al.
Yo-Ichi Yamashita et al.
This chapter covers a range of important topics in the evaluation of the microvascular invasion (MVI) in hepatocellular carcinoma (HCC) before treatment. The malignant potential of HCC is reflected by the types of MVI such as portal venous ...
Serum Amyloid A-Positive Hepatocellular Neoplasm: A New Type of Tumor Arising in Patients with Advanced Alcoholic Disease [0.03%]
血清淀粉样A阳性肝细胞肿瘤：晚期酒精性肝病患者中出现的一种新型肿瘤
Motoko Sasaki,Yasuni Nakanuma
Motoko Sasaki
This chapter reviews a new type of hepatocellular neoplasm, serum amyloid A-positive hepatocellular neoplasm (SAA-HN), which arises in patients with advanced alcoholic liver disease such as cirrhosis. SAA-HNs share histological and immunohi...
Non-Alcoholic Steatohepatitis-Related Hepatocellular Carcinoma: A Growing Epidemic? [0.03%]
非酒精性脂肪肝相关 hepatocellular carcinoma(HCC)：一个日益严重的流行病吗？
Adam C Yopp,Michael A Choti
Adam C Yopp
Within developed countries the incidence of hepatocellular carcinoma (HCC) has been progressively increasing despite diagnosing fewer new cases of cirrhosis linked to viral hepatitis and alcohol consumption. This increased incidence paralle...
Rosina Maria Critelli,Nicola De Maria,Erica Villa
Rosina Maria Critelli
This chapter focuses on the identification of hepatocellular carcinoma (HCC) molecular signatures and the potentials of these signatures in prediction of HCC prognosis and driving of HCC therapeutic treatments. Progress in molecular profili...
Norihiro Kokudo,Yoshikuni Kawaguchi
Norihiro Kokudo
Akishige Kanazawa,Tadashi Tsukamoto,Sadatoshi Shimizu et al.
Akishige Kanazawa et al.
This chapter covers a range of important topics of laparoscopic hepatectomy as a novel approach toward treatment of liver cancer. Although laparoscopic hepatectomy was performed in a limited number of centers in the 1990s, technological inn...