Real-world Dose Escalation and Associated Direct Costs of Biologics in Management of Ulcerative Colitis: A Retrospective Database Study [0.03%]
真实世界生物制剂溃疡性结肠炎管理中的剂量递增及相应的直接成本：一项数据库回顾性研究
Miguel Regueiro,Tania Gulati,Ashmita Bandyopadhyay et al.
Miguel Regueiro et al.
Introduction: Dose escalation with biologics is common among patients with ulcerative colitis (UC). We investigated the dose escalation and associated incremental costs among patients treated with biologics for UC. ...
A comprehensive review of genetic mutations occurring in the development and progression of gastric cancer [0.03%]
胃癌发生发展过程中遗传突变的研究进展综述
Yalan Li,Qianqian Xu,Zhuo Chen et al.
Yalan Li et al.
Background Gastric cancer (GC), a leading cause of mortality globally, is a complex condition stemming from various factors including unhealthy lifestyle habits, genetic mutations expressed in a single nucleotide, environmental effects, and...
Wenchao Li,Yanbing Tian,Lijing Jing
Wenchao Li
Objectives: The purpose of this study was to examine miR-7-5p levels in patients with liver cirrhosis and its correlation with liver function, as well as to evaluate its clinical value as a diagnostic and prognostic bioma...
Tailoring Crohn's disease surveillance in clinical remission: new insights from the Lewis score [0.03%]
临床缓解期克罗恩病患者内镜监测的优化：Lewis评分的新启示
Ana Isabel Ferreira,Tiago Lima Capela,Sofia Xavier et al.
Ana Isabel Ferreira et al.
Introduction: Optimal thresholds for Lewis score in the surveillance of patients with Crohn's disease (CD) in clinical remission remain uncertain. Our aim was to evaluate predictive factors of clinical exacerbation in pat...
Clostridioides difficile infection in Patients Undergoing Acid-Suppressive Treatment: A Large Cohort Study with Propensity Score Matching [0.03%]
奥美拉唑抑酸治疗患者的艰难梭菌感染：大样本队列匹配研究
Ilsoo Kim,Joon Sung Kim,Jae Myung Park et al.
Ilsoo Kim et al.
Introduction: Clostridioides difficile infection (CDI) is a significant concern in patients undergoing acid-suppressive therapy. This study aimed to evaluate and compare the risk of CDI in patients being treated with prot...
Mehwish Ahmed,Pavadee Poowuttikul,William D Chey et al.
Mehwish Ahmed et al.
Background: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated reaction to food well-known in the allergy and immunology literature that presents with delayed gastrointestinal symptoms. It is classi...
Dissection the Hepatitis B Virus Replication Mechanisms and Advances in In Vivo Models: A Comprehensive Review [0.03%]
乙型肝炎病毒复制机制及活体模型研究进展综述
Ashish Kumar Vyas,S Amitha Banu,Kajal Rahangdale et al.
Ashish Kumar Vyas et al.
Chronic infection of the Hepatitis B virus (HBV) is a leading cause of advanced liver diseases. The process of HBV replication and available in-vivo models to study the HBV are very complex. The entry into hepatocytes is a multifaceted inte...
Serum-soluble human leukocyte antigen G serves as a biomarker for early gastric cancer screening among the elderly people [0.03%]
老年人胃癌筛查中可溶性人白细胞抗原G作为生物标志物的作用
Shuangzhen Bao,Xinying Wang,Jiangang Zhao
Shuangzhen Bao
Background: Gastric cancer is a major cause of gastrointestinal cancer deaths, and early detection is key to improving survival. Current diagnostic methods have limitations, highlighting the need for new biomarkers. Our s...
Peri-complication Diagnosis of Nonalcoholic Fatty Liver Disease: A U.S. Population-based Retrospective Analysis [0.03%]
基于人群的非酒精性脂肪肝病并发症回顾性分析
Richie Manikat,Sally Tran,Leslie Yeeman Kam et al.
Richie Manikat et al.
Background: Screening guidelines for nonalcoholic fatty liver disease (MASLD) remain controversial, though early diagnosis can faciliate intervention and prevention. We aimed to determine the proportion of patients with a...