Title: Hans-based cell of origin is not of prognostic significance in DLBCL patients; Retrospective single center study conducted in 326 RCHOP treated patients [0.03%]
基于汉斯分型的起源细胞在DLBCL患者中无预后意义：单中心326例R-CHOP方案治疗患者的回顾性研究
Marianthi Symeonidou,Stergios George Intzes,Konstantinos Zagoridis et al.
Marianthi Symeonidou et al.
Background: Diffuse large B-cell lymphoma (DLBCL) is a highly aggressive lymphoma with dismal outcome after disease progression. Individual risk assessment can stratify patients into different treatment strategies. ...
Anexelekto (Axl)/Mer inhibitor tamnorzatinib in patients with relapsed/refractory acute myeloid leukaemia: Results from a phase I (monotherapy) and phase II (combination with venetoclax) clinical study [0.03%]
AXL/MER抑制剂Tamnorzatinib治疗复发/难治性急性髓系白血病的I期（单药）和II期（与Venclexta联合用药）临床研究结果
Margaret T Kasner,Nigel Courtenay-Luck,Courtney Dinardo et al.
Margaret T Kasner et al.
Introduction: Relapsed/refractory (R/R) acute myeloid leukaemia (AML) is a life-threatening haematological malignancy without effective treatments. Anexelekto (Axl) and Mer receptor tyrosine kinases have emerged as import...
Patients with Prior Cerebral Venous Sinus Thrombosis Presenting to the Emergency Department with Neurological Symptoms- The Yield of Neuroimaging [0.03%]
既往患有脑静脉窦血栓形成的急诊神经症状患者进行影像学检查的阳性率
Evgeny Grishin,Ivan Budnik,Orly Efros et al.
Evgeny Grishin et al.
Introduction: Cerebral venous sinus thrombosis (CVST) is a rare but potentially life-threatening condition. Despite advances in diagnostic imaging and therapeutic strategies, data regarding risk factors for cerebral venou...
Hemophagocytic Syndromes in Adults - Real-World data on Mortality from a tertiary reference center [0.03%]
成人噬血细胞综合征患者的死亡率：来自三级诊疗中心的现实世界数据
Tatiana Wojtovicova,Drahomir Aujesky,Joerg C Schefold et al.
Tatiana Wojtovicova et al.
Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition characterized by excessive immune activation, cytokine storm, and aberrant macrophage function. Although HLH is well studied in children, data on adult HLH remai...
Minimal clonal plasma cell contamination of peripheral stem cell grafts have an adverse prognostic impact in patients with multiple myeloma undergoing autologous transplantation [0.03%]
微小克隆浆细胞对接受自体移植的多发性骨髓瘤患者外周造血干细胞移植物的不利预后影响
Yang Liu,Danyang Shao,Yingjun Chang et al.
Yang Liu et al.
Introduction The significance of autografts' contamination by clonal plasma cells on clinical outcome in newly diagnosed multiple myeloma remains controversial. Methods We retrospectively reviewed the clinical and laboratory data of newly d...
Imatinib Treatment in Primary Acute Basophilic Leukemia with FIP1L1-PDGFRα Rearrangement: A Case Report [0.03%]
伊马替尼治疗FIP1L1-PDGFRα融合阳性原发急性 basophilic 白血病一例报告
Jichao Wu,Jiefang Li,Jun Yin et al.
Jichao Wu et al.
Acute Basophilic Leukemia (ABL) is a rare form of acute leukemia, defined by an elevated number of immature basophils in the peripheral blood. Clinically, it presents with skin infiltration, organ enlargement, osteolytic lesions, and elevat...
Case Reports
Acta haematologica. 2025 Nov 14:1-10. DOI:10.1159/000549406 2025
Diagnosis and Management of Philadelphia-Like Acute Lymphoblastic Leukemia in Adults [0.03%]
成人费城样急性淋巴细胞白血病的诊断和治疗
Hoda Pourhassan,Winston Y Lee,Marc Schwartz et al.
Hoda Pourhassan et al.
Background: The entity of Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) accounts for approximately 20-30% of newly diagnosed adults with B-cell ALL cases in the United States. Compared to other B-cell subtypes...
BCR::ABL1-Like B-Cell Acute Lymphoblastic Leukemia with BCR::PDGFRA Fusion: A Case Report and Literature Review [0.03%]
BCR-ABL1样B细胞急性淋巴细胞白血病合并BCR-PDGFRA融合基因1例及文献复习
Jiamin Hua,Han Yan,Xiangyu Qian et al.
Jiamin Hua et al.
Introduction: We report a case of B-cell acute lymphoblastic leukemia (B-ALL) involving the breakpoint cluster region (BCR) and platelet-derived growth factor receptor alpha (PDGFRA) (BCR::PDGFRA) fusion gene, classified ...
Discrepancies in Treatment Goals and Concerns Regarding Disease Management between Patients with Myeloproliferative Neoplasms and Hematologists in China: Analysis from a Multicenter Cross-Sectional Survey [0.03%]
中国骨髓增生性肿瘤患者与血液科医生在治疗目标上的分歧及疾病管理方面的顾虑：一项多中心横断面调查分析
Junling Zhuang,Hongxia Shi,Xiaoli Liu et al.
Junling Zhuang et al.
Introduction: This study was aimed to identify the discrepancies in treatment goals and concerns regarding disease management between patients with myeloproliferative neoplasms (MPNs) and hematologists. ...
The Causal Relationship between Lipid Metabolites and Multiple Myeloma Risk: A Mendelian Randomization Study [0.03%]
脂质代谢产物与多发性骨髓瘤风险的因果关系：一项孟德尔随机化研究
Jian Tao,Ling Wang,Zheyun Gu
Jian Tao
Introduction: Research has demonstrated a potential link between lipid metabolites and multiple myeloma (MM); however, the causal relationship remains uncertain. This Mendelian randomization (MR) study aimed to explore th...