[From stone-craved genes to Michelangelo: significance and different aspects of gene-environment interaction] [0.03%]
从石刻基因到米开朗基罗——论基因-环境互作的重要性及多面性
Judit Lazary
Judit Lazary
Although genetic studies have improved a lot in recent years, without clinical relevance sometimes their significance is devalued. Reviewing the major milestones of psychogenomics it can be seen that break-through success is just a question...
[Psychobiological background and clinical aspects of the placebo effect in psychiatry] [0.03%]
[心理生物学基础及医学中的安慰剂效应临床方面]
Laszlo Pogany
Laszlo Pogany
The placebo-effect is present in almost every field of medicine, however, in the assessment of the effect of psychotropic drugs it is a major problem. The rise of the placebo-effect in clinical trials is observed during the last decades, in...
[Maternal bonding style, cholinergic receptor gene polymorphisms in association with smoking-related depressive symptoms] [0.03%]
母子依附方式和胆碱能受体基因多态性与吸烟相关抑郁症状的关系研究
Iren Csala,Peter Dome,Judit Lazary
Iren Csala
Backgorund: There is accumulating evidence on the association between the cholinergic system and nicotine dependence (ND) in the literature and the bidirectional relationship of ND and depression. However, the molecular background of the de...
[Vascular endothelial growth factor (VEGF) as a potential biomarker in major depressive disorder] [0.03%]
[血管内皮生长因子(VEGF)作为抑郁症潜在生物标志物的可能性]
Monika Elemery,Szilvia Kiss,Xenia Gonda et al.
Monika Elemery et al.
Background: There is growing evidence that vascular endothelial growth factor (VEGF) plays a crucial role in neurodevelopment and regeneration. Several data support that intact VEGF pathway is indispensable for therapeuti...
[Genetic association analyses of the endocannabinoid system on anxious phenotype] [0.03%]
内源大麻素系统与焦虑表型的遗传关联分析
Judit Lazary,Nora Eszlari,Gabriella Juhasz et al.
Judit Lazary et al.
Background: Accumulating data confirmed that the endocannabinoid system (ECS) is involved in the regulation of stress response and emotional processes, therefore ECS became an important pharmacological target as a potenti...
New aspects in the pathomechanism of diseases of civilization, particularly psychosomatic disorders. Part 2. Chronic hypocapnia and hypercapnia in the medical practice [0.03%]
文明病尤其是心身疾病病理机制的新方面(第二部分)医疗实践中的慢性低碳酸血症和高碳酸血症
Andras Sikter,Zoltan Rihmer,Roberto de Guevara
Andras Sikter
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (S...
Anna Szucs,Andras Horvath,Daniel Fabo et al.
Anna Szucs et al.
The frequent psychiatric comorbidity in epilepsy compromises the quality of life of those affected, further increasing their suicide risk and the high burden of stigmatisation. Out of adulthood epilepsies, mesio-temporal lobe epilepsy carri...
Peter Torzsa,Csenge Hargittay,Laszlo Kalabay
Peter Torzsa
Representative studies indicate that prevalence of anxiety disorders among adults is between 12.6-17.2%, while in Hungary it is 17.7%. According to both international and national studies the point prevalence of diagnosed major depression r...
[Assessing suicide risk based on a hierarchical classification of risk factors] [0.03%]
基于风险因素的层次分类评估自杀的风险性
Zoltan Rihmer,Peter Dome,Xenia Gonda et al.
Zoltan Rihmer et al.
Suicide risk factors could be organised into a hierarchical order and a questionnaire constructed based on this hierarchical structure may help clinicians assess suicide risk. The paper presents analysis of the clinical utility of a questio...
[About the association between antipsychotic medication and cardiovascular morbidity: epidemiology and possible background mechanisms] [0.03%]
关于抗精神病药物与心血管疾病关联的流行病学及可能的作用机制
Gabor Gaszner,Gabor Barna,Peter Dome
Gabor Gaszner
The history of antipsychotics began with the discovery of chlorpromazine in the 1950s. Since then this group of medications has become one of the most important element of the armamentarium of psychopharmacology. While initially these pharm...