Spinal Cord and Central Nervous System Distribution of Epidural Oxycodone-Experimental Pregnant Sheep Model [0.03%]
腰麻吗啡的脊髓和中枢神经系统分布--妊娠羊实验模型研究
Anna Haataja,Henriikka Hakomäki,Hannu Kokki et al.
Anna Haataja et al.
Background: Epidural oxycodone is a highly effective analgesic. However, oxycodone's distribution in the spinal cord after epidural injection is not known. In this experimental study, we evaluated the segmental spinal cor...
The Danish Out-of-Hospital Cardiac Arrest Trial: A Statistical Analysis Plan [0.03%]
丹麦院外心脏骤停试验：统计分析计划
Simon Mølstrøm,Jacob E Møller,Henrik Schmidt et al.
Simon Mølstrøm et al.
Background: Post-cardiac arrest care for patients resuscitated from out-of-hospital cardiac arrest (OHCA) includes multiple pharmacological and physiological interventions, yet optimal strategies to reduce post-cardiac ar...
Randomized Controlled Trial
Acta anaesthesiologica Scandinavica. 2026 Aug;70(7):e70288. DOI:10.1111/aas.70288 2026
Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) Trial [0.03%]
在院外心脏骤停幸存昏迷患者中，与安慰剂相比预防性使用奥氮平的多中心随机对照研究——“丹麦院外心脏骤停”（DANOHCA）试验中的研究方案
Benedikte Liebetrau,Anders M Grejs,Martin A S Meyer et al.
Benedikte Liebetrau et al.
Background: Delirium is a frequent complication in comatose Out-of-Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. De...
Søren Søndergaard
Søren Søndergaard
Glucagon-Like Peptide-1 Agonist vs. Placebo and Pulmonary Decline After Open-Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial [0.03%]
glucagon-like肽-1受体激动剂与安慰剂对心脏手术后肺功能下降的影响：GLORIOUS随机临床试验的亚组分析
Astrid Duus Mikkelsen,Sebastian Wiberg,Hans Henrik Lawaetz Schultz et al.
Astrid Duus Mikkelsen et al.
Background: Postoperative pulmonary decline is an established complication of open-heart surgery extending beyond the immediate postoperative phase. Inflammation-mediated lung damage and ischaemia-reperfusion injury secon...
Randomized Controlled Trial
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70282. DOI:10.1111/aas.70282 2026
Remifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation-The ROCVIDEO Trial Protocol [0.03%]
瑞芬太尼与罗库溴铵优化可视喉镜气管插管的临床研究——ROCVIDEO试验方案
Emil Ørskov Ipsen,Lars Hyldborg Lundstrøm,Åse Lodenius et al.
Emil Ørskov Ipsen et al.
Background: Routine use of neuromuscular blocking agents (NMBAs) is widely recommended to facilitate tracheal intubation. However, NMBA use is associated with potential adverse effects, including postoperative respiratory...
Establishing Expert Consensus on Competencies for Safe Ward-Based Postoperative Epidural Analgesia Management: Protocol for a Modified Delphi Study [0.03%]
围手术期术后病房患者 epidural 镇痛安全管理能力专家共识的建立：混合式德尔菲研究方案
Cornelia Charlotte Lamprecht,Søs Bohart,Kim Wildgaard et al.
Cornelia Charlotte Lamprecht et al.
Postoperative epidural analgesia (EA) is an important analgesic strategy for selected surgical procedures. However, clinical practice and training vary across settings, and no consensus-based framework currently defines the competencies req...
Subcutaneous Tranexamic Acid Achieves Comparable Serum Concentrations to Intramuscular Administration During Haemorrhagic Shock in a Swine Model [0.03%]
在猪出血性休克模型中，纤维蛋白胶注射透明质酸氨实现与肌肉注射相当的血药浓度
Trine Lynghaug,Ole Martin Fuskevåg,Benjamin Stage Storm et al.
Trine Lynghaug et al.
Background: Tranexamic acid is an antifibrinolytic agent reducing mortality when administered to trauma patients with haemorrhagic shock. This mortality reduction is time sensitive. Increased intramuscular dose administra...
Comparative Study
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70274. DOI:10.1111/aas.70274 2026
Developing a Core Outcome Measurement Set for Adult ICU Patients, the CoreMS-ICU-A Protocol [0.03%]
成年重症监护病房患者核心结果测量集的开发，CoreMS-ICU-A方案
Maj-Brit Nørregaard Kjær,Camilla Rahbek Lysholm Bruun,Camilla Bekker Mortensen et al.
Maj-Brit Nørregaard Kjær et al.
Background: Core outcome measurement sets (COMS) enhance the consistency and comparability of outcome reporting in clinical research. However, their effectiveness depends on the selection of valid, reliable, and feasible ...
Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE): A Protocol for a Pre-Planned Sub-Study of a Randomized Clinical Trial [0.03%]
心脏骤停后镇静、体温和血压对主要肾不良事件的影响：一项随机对照临床试验的预计划子研究方案(STEPCARE-MAKE)
Keski-Keturi M,Niemelä V H,Young P et al.
Keski-Keturi M et al.
Background: Acute kidney injury (AKI) is a common and serious complication after cardiac arrest, affecting more than 30% of initially successfully resuscitated patients, with around 10% receiving Kidney Replacement Therap...