Pantoprazole Use in Invasively Ventilated Patients With Septic Shock: A Protocol and Statistical Analysis Plan [0.03%]
关于使用泮托拉唑治疗重症监护病房中脓毒性休克患者的临床研究方案及统计分析计划
Akira Kuriyama,Diane Heels-Ansdell,Shannon M Fernando et al.
Akira Kuriyama et al.
Sepsis is a recognized risk factor for upper gastrointestinal bleeding, yet sepsis-specific randomized evidence informing stress ulcer prophylaxis remains limited. This protocol describes the rationale, methods, and statistical analysis pla...
Glucocorticoids for Patients With Acute Decompensated Heart Failure: A Protocol for a Systematic Review With Meta-Analysis and Trial Sequential Analysis [0.03%]
糖皮质激素治疗急性心衰患者：系统评价和 meta 分析及序贯试验分析方案
Laura Wrisberg Kæstel,Isak Mazanti Cold,Danni Herman Andersen et al.
Laura Wrisberg Kæstel et al.
Background: Acute decompensated heart failure (ADHF) is associated with inflammation. Inflammatory biomarkers in patients with ADHF are associated with increased mortality. Glucocorticoids mitigate systemic inflammation a...
Digital Versus in-Person Pre-Anaesthetic Assessment and Postoperative Outcomes in Low-Risk Patients: A Protocol for a Single-Centre Cohort Study [0.03%]
低风险患者数字和面对面麻醉前评估及术后结果的单中心队列研究方案：一项针对低风险患者的数字与面对面术前麻醉评估以及术后结局的单中心队列研究方案
Mathilde Nellemann,Moritz Kilian German Denneborg,Sofie Amalie Bosholdt et al.
Mathilde Nellemann et al.
Pre-anaesthetic assessment is essential for identifying perioperative risk and optimising patient safety. Digital alternatives, including video consultation and structured electronic health record (EHR) review, may improve efficiency, but c...
Comparative Study
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70266. DOI:10.1111/aas.70266 2026
ICU Clinicians' View on Platelet Transfusion Thresholds for a Future Trial-Protocol for an International Survey [0.03%]
重症监护医师对未来血小板输注试验的看法-国际调查协议书
Jehad Ahmad Barakji,Carl Thomas Anthon,Anders Granholm et al.
Jehad Ahmad Barakji et al.
Background: Thrombocytopenia is frequent in adult intensive care unit (ICU) patients and may contribute to adverse outcomes, including bleeding, morbidity and mortality. To reduce the risk of bleeding, platelet transfusio...
Swedish Intensive Care Physicians' Attitudes Towards Withholding or Withdrawing Life-Sustaining Treatment in Critically Ill Children [0.03%]
瑞典重症医师对拒绝或撤回生命支持治疗的态度——针对重症儿童患者的研究
Maria Ahlerup,Johan Malmgren,Albert Gyllencreutz Castellheim et al.
Maria Ahlerup et al.
Background: Decisions to withhold or withdraw life-sustaining treatments for critically ill children are challenging. This study aims to identify Swedish intensivists' attitudes, values and experiences towards the decisio...
Association of Suspected Aspiration During of Out-Of-Hospital Cardiac Arrest With Development of Early-Onset Pneumonia [0.03%]
院外心脏骤停疑似误吸与早期肺炎发病之间的关联性分析
Karoliina Yli-Luukko,Paula Mäki,Sanna Hoppu et al.
Karoliina Yli-Luukko et al.
Background: Early-onset pneumonia is a possible complication after out-of-hospital cardiac arrest (OHCA) resuscitation. Whether or not a suspected aspiration during prehospital care is associated with the development of e...
Observational Study
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70257. DOI:10.1111/aas.70257 2026
A Systematic Review and Expert Evaluation of Perioperative SGLT2 Inhibitor-Associated Ketoacidosis Case Reports [0.03%]
围手术期SGLT2抑制剂相关酮症酸中毒病例报告的系统评价和专家评估
L I P Snel,X Li,F Jamaludin et al.
L I P Snel et al.
Introduction: The use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in the perioperative setting may lead to SGLT2i-associated postoperative ketoacidosis (SAPKA) in patients with type 2 diabetes (T2D). Therefore, ...
Malignant Hyperthermia in Sweden: Clinical Presentations and Genetic Findings [0.03%]
瑞典的恶性高热：临床表现和基因发现
Anna Hellblom,Maria Soller,Carolina Samuelsson
Anna Hellblom
Introduction: Malignant hyperthermia (MH) is a pharmacogenetic, hypermetabolic and potentially lethal reaction to potent volatile anaesthetics and the muscle relaxant succinylcholine. To improve the understanding of MH, t...
Ultrasound-Guided Superficial Parasternal Intercostal Plane Block for Early Pain Management in Patients Undergoing Cardiac Surgery-A Randomized Controlled Trial [0.03%]
超声引导浅层胸骨旁肋间平面阻滞用于心脏手术后早期镇痛：一项随机对照试验
Antti-Johannes Kalli,Pekka Mäkelä,Heini Huhtala et al.
Antti-Johannes Kalli et al.
Background: Sternotomy causes substantial postoperative pain. Recently, several less invasive nerve blocks have been described that are safer to use even on anticoagulated patients. This study aims to evaluate early pain ...
Randomized Controlled Trial
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70253. DOI:10.1111/aas.70253 2026
Whole Blood Transcriptomic Response to Perioperative Dexamethasone in Total Knee Arthroplasty: A Targeted Panel Analysis [0.03%]
全膝关节置换术中围手术期使用地塞米松的全血转录组反应的靶向面板分析
Asger Krog Mølgaard,Kasper Smidt Gasbjerg,Lukas Balsevicius et al.
Asger Krog Mølgaard et al.
Background: Changes in the transcriptome of immune cells are predictive of clinical outcomes. These effects may be surgery-specific and possibly modulated by glucocorticoids. We investigated the immune response and the im...
Randomized Controlled Trial
Acta anaesthesiologica Scandinavica. 2026 Jul;70(6):e70244. DOI:10.1111/aas.70244 2026