Alpha-1 antitrypsin treatment of new-onset type 1 diabetes: An open-label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics [0.03%]
治疗新发1型糖尿病的α1抗胰蛋白酶治疗：一项开放标签1期临床试验（保留试验），以评估安全性和药代动力学
Gordon C Weir,Mario R Ehlers,Kristina M Harris et al.
Gordon C Weir et al.
Objective: To determine the safety and pharmacokinetics of alpha-1 antitrypsin (AAT) in adults and children. Research design and methods: ...
Clinical Trial
Pediatric diabetes. 2018 Aug;19(5):945-954. DOI:10.1111/pedi.12660 2018
Viviana Bauman,Adaya C Sturkey,Rosa Sherafat-Kazemzadeh et al.
Viviana Bauman et al.
Background: Factitious hypoglycemia is a condition of self-induced hypoglycemia due to surreptitious administration of insulin or oral hypoglycemic agents. In adults, it is an uncommon, but well known clinical entity obse...
Intensive remote monitoring versus conventional care in type 1 diabetes: A randomized controlled trial [0.03%]
1型糖尿病的强化远程监控与常规照护的对比：随机对照试验
Laura Gandrud,Aylin Altan,Paul Buzinec et al.
Laura Gandrud et al.
Objective: While frequent contact with diabetes care providers may improve glycemic control among patients with type 1 diabetes (T1D), in-person visits are labor-intensive and costly. This study was conducted to assess th...
A plateau in new onset type 1 diabetes: Incidence of pediatric diabetes in the United States Military Health System [0.03%]
美国军事医疗系统中儿童糖尿病发病率：1型糖尿病初发的平台期
Toni Rush,Megan McGeary,Nicholas Sicignano et al.
Toni Rush et al.
Objectives: To describe the incidence and prevalence of type 1 diabetes among pediatric dependents of the US Department of Defense. Methods: ...
Long-term study of tubeless insulin pump therapy compared to multiple daily injections in youth with type 1 diabetes: Data from the German/Austrian DPV registry [0.03%]
一项关于青少年轻度糖尿病患者无导管胰岛素泵治疗与多次皮下注射治疗的长期对比研究：来自德国/奥地利DPV登记数据库的数据分析
Thomas Danne,Anke Schwandt,Torben Biester et al.
Thomas Danne et al.
Objective: To examine glycemic control in youth with type 1 diabetes (T1D) who switched from multiple daily injections (MDI) to a tubeless insulin pump (Omnipod Insulin Management System, Insulet Corporation, Billerica, M...
Comparative Study
Pediatric diabetes. 2018 Aug;19(5):979-984. DOI:10.1111/pedi.12658 2018
Effects of residential summer camp on body mass index and body composition in type 1 diabetes [0.03%]
夏令营对1型糖尿病患者体质指数和身体组成的影响
Jon D Oden,Brian Franklin,Ernesto Fernandez et al.
Jon D Oden et al.
Background: Body mass index (BMI) and fat mass may be higher in children with diabetes compared to healthy peers. It is not certain how diabetic children respond to exercise and diet interventions. ...
Beta cell function after intensive subcutaneous insulin therapy or intravenous insulin infusion at onset of type 1 diabetes in children without ketoacidosis [0.03%]
儿童1型糖尿病起病时无酮症酸中毒患儿强化皮下胰岛素治疗或起病时静脉输注胰岛素对β细胞功能的影响
Rebecka Enander,Peter Adolfsson,Torun Bergdahl et al.
Rebecka Enander et al.
Background: Our aim was to see if IV insulin therapy at diagnosis preserves beta-cell function better than multiple subcutaneous (SC) injections. Methods:...
Whole-exome sequencing for mutation detection in pediatric disorders of insulin secretion: Maturity onset diabetes of the young and congenital hyperinsulinism [0.03%]
儿童胰岛素分泌障碍的全外显子组测序检测突变：青年发病型糖尿病和先天性高胰岛素血症
S R Johnson,P J Leo,A M McInerney-Leo et al.
S R Johnson et al.
Background: To assess the utility of whole-exome sequencing (WES) for mutation detection in maturity-onset diabetes of the young (MODY) and congenital hyperinsulinism (CHI). MODY and CHI are the two commonest monogenic di...
Oral contraception in adolescents with type 1 diabetes and its association with cardiovascular risk factors. A multicenter DPV study on 24 011 patients from Germany, Austria or Luxembourg [0.03%]
口服避孕药与1型糖尿病青少年心血管危险因素的关系——德国、奥地利和卢森堡24011例患者的多中心DPV研究
Barbara Bohn,Kirsten Mönkemöller,Dörte Hilgard et al.
Barbara Bohn et al.
Objective: To investigate differences in cardiovascular risk factors and metabolic control in girls with type 1 diabetes with or without use of oral contraceptives (OC) from the multicenter "diabetes prospective follow-up...
Multicenter Study
Pediatric diabetes. 2018 Aug;19(5):937-944. DOI:10.1111/pedi.12656 2018
The contribution of physical fitness to individual and ethnic differences in risk markers for type 2 diabetes in children: The Child Heart and Health Study in England (CHASE) [0.03%]
身体素质对英国儿童2型糖尿病风险因素的个体和种族差异的贡献：英国儿童心脏与健康研究(CHASE)
Claire M Nightingale,Alicja R Rudnicka,Sarah R Kerry-Barnard et al.
Claire M Nightingale et al.
Background: The relationship between physical fitness and risk markers for type 2 diabetes (T2D) in children and the contribution to ethnic differences in these risk markers have been little studied. We examined associati...