Early childhood infections precede development of beta-cell autoimmunity and type 1 diabetes in children with HLA-conferred disease risk [0.03%]
人类白细胞抗原易感儿童中，早期感染与β细胞自身免疫和1型糖尿病发病相关性研究
N Mustonen,H Siljander,A Peet et al.
N Mustonen et al.
Background: The etiology of type 1 diabetes (T1D) is largely unknown. Infections and microbial exposures are believed to play a role in the pathogenesis and in the development of islet autoimmunity in genetically suscepti...
Observational Study
Pediatric diabetes. 2018 Mar;19(2):293-299. DOI:10.1111/pedi.12547 2018
Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity [0.03%]
初发自身抗体和1型糖尿病诊断时的自身抗体作为疾病异质性的标志物
Jorma Ilonen,Johanna Lempainen,Anna Hammais et al.
Jorma Ilonen et al.
Objective: The relationship between patterns of islet autoantibodies at diagnosis and specificity of the first islet autoantibody at the initiation of autoimmunity was analyzed with the aim of identifying patterns informa...
Comparative Study
Pediatric diabetes. 2018 Mar;19(2):284-292. DOI:10.1111/pedi.12545 2018
Comprehensive screening for monogenic diabetes in 89 Japanese children with insulin-requiring antibody-negative type 1 diabetes [0.03%]
对89名抗体阴性的1型糖尿病日本患儿进行单基因糖尿病的全面筛查
Kikumi Ushijima,Maki Fukami,Tadayuki Ayabe et al.
Kikumi Ushijima et al.
Background: Mutations in causative genes for neonatal diabetes or maturity-onset diabetes of the young have been identified in multiple patients with autoantibody-negative type 1 diabetes (T1D). ...
Ketoacidosis at onset of type 1 diabetes is a predictor of long-term glycemic control [0.03%]
1型糖尿病初发时的酮症酸中毒可预测长期血糖控制水平
Shlomit Shalitin,Sharon Fisher,Michal Yackbovitch-Gavan et al.
Shlomit Shalitin et al.
Background: Few studies have evaluated the impact of diabetic ketoacidosis (DKA) at diabetes onset on long-term glycemic control in patients with type 1 diabetes (T1D). ...
Comparative Study
Pediatric diabetes. 2018 Mar;19(2):320-328. DOI:10.1111/pedi.12546 2018
Prevention of complications in glycogen storage disease type Ia with optimization of metabolic control [0.03%]
优化代谢控制在葡萄糖贮积病Ia型并发症预防中的作用
M Dambska,E B Labrador,C L Kuo et al.
M Dambska et al.
Prior to 1971, type Ia glycogen storage disease was marked by life-threatening hypoglycemia, lactic acidosis, severe failure to thrive, and developmental delay. With the introduction of continuous feeds in the 1970s and cornstarch in the 19...
Mortality in type 1 diabetes diagnosed in childhood in Northern Ireland during 1989-2012: A population-based cohort study [0.03%]
1989年至2012年北爱尔兰确诊的儿童1型糖尿病死亡率：基于人口队列的一项研究
Eileen Morgan,Catherine R Black,Noina Abid et al.
Eileen Morgan et al.
Objective: To investigate long-term mortality rates and causes of death in individuals diagnosed with type 1 diabetes before the age of 15 years during the period 1989-2012 or known to paediatric diabetes teams in 1989, i...
Ketoacidosis at diagnosis of type 1 diabetes: Effect of prospective studies with newborn genetic screening and follow up of risk children [0.03%]
初诊1型糖尿病患儿出现酮症酸中毒：新生儿遗传筛查和高危儿童随访前瞻性研究的影响
Anne M Hekkala,Jorma Ilonen,Jorma Toppari et al.
Anne M Hekkala et al.
We studied the frequency of diabetic ketoacidosis (DKA) in children at diagnosis of type 1 diabetes (T1D) in a region where newborn infants have since 1995 been recruited for genetic screening for human leukocyte antigen (HLA)-conferred dis...
Observational Study
Pediatric diabetes. 2018 Mar;19(2):314-319. DOI:10.1111/pedi.12541 2018
Insulinaemia and insulin resistance in Caucasian general paediatric population aged 2 to 10 years: Associated risk factors [0.03%]
2至10岁白人儿科人群中胰岛素血症和胰岛素抵抗的相关危险因素分析
Irene Alías-Hernández,Rafael Galera-Martínez,Emilio García-García et al.
Irene Alías-Hernández et al.
Background: The aim of this study is to determine values of insulinaemia, homeostasis model assessment (HOMA) index and quantitative insulin sensitivity check index (QUICKI) among a population of prepubertal Caucasian chi...
Observational Study
Pediatric diabetes. 2018 Feb;19(1):45-52. DOI:10.1111/pedi.12533 2018
Glycosuria and hyperglycemia in the neonatal period as the first clinical sign of Fanconi-Bickel syndrome [0.03%]
新生儿期出现尿糖和高血糖作为Fanconi-Bickel综合征的首发临床表现
María Pilar Bahíllo-Curieses,Rebeca Garrote-Molpeceres,María Miñambres-Rodríguez et al.
María Pilar Bahíllo-Curieses et al.
Fanconi-Bickel syndrome is a rare inherited disease characterized by the combination of hepatorenal glycogen accumulation, proximal renal tubular dysfunction and impaired utilization of glucose and galactose. The first symptoms of the disor...
Case Reports
Pediatric diabetes. 2018 Feb;19(1):180-183. DOI:10.1111/pedi.12531 2018
Dietary sodium intake relates to vascular health in children with type 1 diabetes [0.03%]
饮食中的钠摄入量与1型糖尿病患儿的血管健康状况有关
Jemma Anderson,Jennifer J Couper,Sarah Toome et al.
Jemma Anderson et al.
Background and objective: Children with type 1 diabetes (T1D) have vascular dysfunction and frequently struggle to adhere to dietary recommendations. Limited data exist for the vascular consequences of poor diet quality i...