A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα [0.03%]
一种新型铜配合物被识别为针对结直肠癌和乳腺癌细胞的有效药物及人类拓扑异构酶IIα的抑制剂
Shayna Sandhaus,Rosella Taylor,Tiffany Edwards et al.
Shayna Sandhaus et al.
A novel complex, [Cu(acetylethTSC)Cl]Cl•0.25C2H5OH 1 (where acetylethTSC = (E)-N-ethyl-2-[1-(thiazol-2-yl)ethylidene]hydrazinecarbothioamide), was shown to have anti-proliferative activity against various colon and aggressive breast cancer...
Synthesis, structural studies, and oxidation catalysis of the manganese(II), iron(II), and copper(II) complexes of a 2-pyridylmethyl pendant armed side-bridged cyclam [0.03%]
含2-吡啶甲基臂架侧桥环糊精配体的锰(II)、铁(II)和铜(II)配合物的合成、结构研究及催化氧化性能
Anthony D Shircliff,Kevin R Wilson,Desiray J Cannon et al.
Anthony D Shircliff et al.
The first 2-pyridylmethyl pendant armed structurally reinforced cyclam ligand has been synthesized and successfully complexed to Mn2+, Fe2+, and Cu2+ cations. X-ray crystal structures were obtained for the diprotonated ligand and its Cu2+ c...
Design, synthesis and characterization of a modular bridging ligand platform for bio-inspired hydrogen production [0.03%]
模块化桥联配体平台的生物启发式设计、合成及表征用于产氢反应
Christoph Topf,Uwe Monkowius,Günther Knör
Christoph Topf
Synthesis and characterization of a novel type of ambident bridging ligands joining together the functional prerequisites for visible-light absorption, photoinduced electron transfer and catalytic proton reduction is presented. This class o...
Musabbir A Saeed,Avijit Pramanik,Md Alamgir Hossain
Musabbir A Saeed
Structural characterization of the phosphate complex with a thiophene-based macrocycle suggests that two dihydrogen phosphates in a dimeric form are encapsulated in the cavity via several hydrogen bonds from NH···O and CH···O interact...
Transition metal ion capture using functional mesoporous carbon made with 1,10-phenanthroline [0.03%]
2-苯并吡啶功能介孔碳的制备及过渡族金属离子的捕获研究
Wilaiwan Chouyyok,Wassana Yantasee,Yongsoon Shin et al.
Wilaiwan Chouyyok et al.
Functional mesoporous carbon has been built using 1,10-phenanthroline as the fundamental building block, resulting in a nanoporous, high surface area sorbent capable of selectively binding transition metal ions. This material had a specific...
Metal-organic frameworks constructed from monomeric, dimeric and trimeric phenanthroline citrate zinc building units [0.03%]
由单聚体、双聚体和三聚体菲咯啉柠檬酸锌构建单元构筑的金属有机框架
Rong-Hua Zhang,Wen-Sheng Xia,Hong-Xin Wang et al.
Rong-Hua Zhang et al.
Adduct of mononuclear and dinuclear citrate zinc complex [Zn(Hcit)(phen)(H2O)][Zn2(Hcit)(phen)2(H2O)3]·13.5H2O (1) and its aggregate [Zn3(Hcit)2(phen)4]n·14nH2O (2) (H4cit = citric acid, phen = 1,10-phenanthroline) were synthesized in wea...
Oxidative quenching within photosensitizer-acceptor dyads based on bis(bidentate) phosphine-connected osmium(II) bipyridyl light absorbers and reactive metal sites [0.03%]
基于双齿膦连接的锇（II）联吡啶光吸收体和反应性金属位点的光敏剂受体二聚体内的氧化淬灭作用
Sylvia Eller,Barbara Trettenbrein,Dennis Oberhuber et al.
Sylvia Eller et al.
For the first time oxidative quenching of OsP2N4 chromophores by reactive PtII or PdII sites containing cis, trans, cis-1,2,3,4-tetrakis(diphenylphosphino)cyclobutane (dppcb) is directly observed despite the presence of a saturated cyclobut...
Anticancer activity and biophysical reactivity of copper complexes of 2-(benzo[d][1,3]dioxol-5-ylmethylene)-N-alkylhydrazinecarbothioamides [0.03%]
2-(苯并二氧戊英-5-亚甲基)-N-烷基碳硫氨基甲酰腙铜复合物的抗肿瘤活性和生物物理反应性
Floyd A Beckford,Jeffrey Thessing,Alyssa Stott et al.
Floyd A Beckford et al.
A series of copper complexes were synthesized from benzo[d][1,3]dioxole-5-carbaldehyde (piperonal) thio-semicarbazones (RHpTSC where R=H, CH3, C2H5 or C6H5 (Ph)). The complexes show interesting variations in geometry depending on the thiose...
Improved deposition and deprotection of silane tethered 3,4 hydroxypyridinone (HOPO) ligands on functionalized nanoporous silica [0.03%]
改进3,4-羟基吡啶-N，O-二羰酸（HOPO）配体在功能化纳米多孔二氧化硅表面的沉积和脱保护方法
Joseph D Davidson,Robert J Wiacek,Sarah Burton et al.
Joseph D Davidson et al.
An improved synthesis of a 3,4 hydroxypyridinone (HOPO) functionalized mesoporous silica is described. Higher 3,4-HOPO monolayer ligand loadings have been achieved, resulting in better performance. Performance improvements were demonstrated...
Titanium doping reduces superoxide dismutase activity, but not oxidase activity, of catalytic CeO(2) nanoparticles [0.03%]
钛掺杂降低了催化型二氧化铈纳米粒子的超氧化物歧化酶活性，但不影响其氧化酶活性
Aiping Zhu,Kai Sun,Howard R Petty
Aiping Zhu
In this paper we report the enzymatic properties of Ti-doped CeO(2) nanoparticles. The superoxide dismutase activity of Ti-doped nanoparticles is reduced in comparison to undoped nanoceria. In contrast, the oxidase activity of these nanopar...