NeuProIO: A dual-Action Solid Drug Nanoparticle Topical Formulation for Simultaneous Intraocular Pressure Reduction and Neuroprotection for Glaucoma [0.03%]
用于青光眼降低眼压和神经保护的双重作用固体药物纳米颗粒外用制剂NeuProIO
Lei Xu,Mu Li,Lin Qi et al.
Lei Xu et al.
Glaucoma is a leading cause of irreversible blindness, primarily due to elevated intraocular pressure (IOP) that damages the retina and optic nerve. Most topical glaucoma treatments focus solely on IOP-lowering without direct neuroprotectio...
Anti-biofouling organogel and substrate independent coatings with a continuous lubricating network [0.03%]
一种抗生物污染的有机凝胶及不受基材影响且具有连续润滑作用的涂层
Myddelton C Parker,Arpita Shome,Vicente D Pinon et al.
Myddelton C Parker et al.
Organogels have distinct advantages over hydrogels in terms of solvent compatibility, mechanical robustness, prolonged thermal and environmental durability, and affinity for hydrophobic compounds. However, organogels have yet to replace hyd...
Investigating Nanoparticle Distribution and Tissue Architecture in Male and Female Human Cardiac Organoids [0.03%]
人源心脏类器官中纳米颗粒分布及组织结构的性别差异研究
Shaun Grumelot,Freyda Mannering,Nathan Campbell et al.
Shaun Grumelot et al.
Nanoparticles (NPs) are increasingly recognized as vital tools in targeted cardiac therapies, diagnostics, and tissue regeneration. Despite notable advancements, a comprehensive understanding of NP interactions within cardiac tissue as a wh...
Sonia Norouzi Esfahany,Alireza Mahjoubnia,Zehua Chen et al.
Sonia Norouzi Esfahany et al.
Tissue adhesive materials for biomedical applications demand exceptional stretchability, flexibility, and robust adhesion. Herein, we introduce a bioadhesive shape memory elastomer (SME) that is 4D printed by digital light processing (DLP)....
Biofilm comes back: Controlling regrowth by mitigating the cell-matrix interaction [0.03%]
生物膜回来了：通过缓解细胞-基质相互作用来控制再生长
Yu-Heng Deng,Joo Hun Lee,Myung-Joo Kim et al.
Yu-Heng Deng et al.
Biofilms wield a notorious impact on biological infections and environmental sanitation in daily life. Tremendous efforts have been made to develop antimicrobial agents that effectively kill bacterial cells, but preventing biofilm reformati...
Enhancing kitchen waste composting by cellulolytic microorganisms: New insights from quorum sensing and carbohydrates metabolic functions [0.03%]
芽孢杆菌的聚集感应系统及糖代谢在厨余垃圾堆肥化中的作用机制研究
Haimin Li,Changqing Liu,Xingguang Luo et al.
Haimin Li et al.
Quorum sensing (QS) is a critical microbial communication mechanism. This study specifically investigates how brown-rot fungi (BRF), cellulolytic nitrogen-fixing bacteria (CNFB), and their composite microbial inoculants (CMI) regulate QS pr...
Image-Guided Cardiac Regeneration via a 3D Bioprinted Vascular Patch with Built-in CT Visibility [0.03%]
基于内置CT可视化技术的3D生物打印血管贴片引导心脏再生
Carmen J Gil,Alex J Allphin,Linqi Jin et al.
Carmen J Gil et al.
Cardiac patch-based regenerative therapies have shown great promise in the treatment of myocardial infarction (MI). The clinical applications of patch devices, however, face major limitations mainly due to the inadequate integration of typi...
Cellular-level insight into biointerface: From surface charge modulation to boosted photocatalytic oxidative disinfection [0.03%]
细胞水平的生物界面洞察：从表面电荷调节到增强光催化氧化消毒
Zan Zhu,Liang Bao,Dmitry Pestov et al.
Zan Zhu et al.
Photocatalytic oxidative disinfection (POD) towards pathogenic bacteria has become a popular approach in public health due to its environmentally friendly antimicrobial capabilities. However, this approach is still limited by inherent fast ...
The Permanganate-Oxalate Reaction as a Visual Time-Temperature Indicator: Reaction Systems for Use Above 0 °C [0.03%]
高0℃使用的可视温时指示反应体系——高锰酸盐-草酸盐反应
Jorvani Cruz Villarreal,Emil Ljungberg,Aaron G Uy et al.
Jorvani Cruz Villarreal et al.
Biological molecules are often unstable at non-ideal temperatures, causing product inefficacy or false leads in research. Cost-effective, easily implemented tools are needed to ensure the quality of biological products and specimens requiri...
AI-Driven Prediction of Cardio-Oncology Biomarkers Through Protein Corona Analysis [0.03%]
基于蛋白质冠分析的心脏肿瘤生物标志物的AI预测模型
Avirup Guha,Seyed Amirhossein Sadeghi,Harikrishnan Hyma Kunhiraman et al.
Avirup Guha et al.
Protein corona, a layer predominantly composed of proteins and other biomolecules that forms on nanoparticle surfaces upon interaction with biological fluids, has recently been extensively utilized to enhance the depth of plasma proteomics ...