Integrating data to acquire new knowledge: Three modes of integration in plant science [0.03%]
数据整合获取新知识:植物科学研究中的三种集成模式
Sabina Leonelli
Sabina Leonelli
This paper discusses what it means and what it takes to integrate data in order to acquire new knowledge about biological entities and processes. Maureen O'Malley and Orkun Soyer have pointed to the scientific work involved in data integrat...
Elihu M Gerson
Elihu M Gerson
By what mechanisms of organizational and institutional change do different specialties succeed in accommodating and working with one another? How do these mechanisms function over time to support and retard the emergence and stability of ne...
From molecules to behavior and the clinic: Integration in chronobiology [0.03%]
从分子到行为和临床:chrono生物学中的整合问题
William Bechtel
William Bechtel
Chronobiology, especially the study of circadian rhythms, provides a model scientific field in which philosophers can study how investigators from a variety of disciplines working at different levels of organization are each contributing to...
Maureen A OMalley
Maureen A OMalley
Much is being written these days about integration, its desirability and even its necessity when complex research problems are to be addressed. Seldom, however, do we hear much about the failure of such efforts. Because integration is an on...
Sydney Brenner
Sydney Brenner
The following text is an edited version of a recent interview with Sydney Brenner who has been at the forefront of many developments in molecular biology since the 1950s. It provides a participant's view on current issues in the history and...
Alexander Powell,John Dupré
Alexander Powell
Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-sca...
Edna Suárez-Díaz
Edna Suárez-Díaz
This paper focuses on the consolidation of Molecular Evolution, a field originating in the 1960s at the interface of molecular biology, biochemistry, evolutionary biology, biophysics and studies on the origin of life and exobiology. The cla...
Phosphorus-32 in the Phage Group: radioisotopes as historical tracers of molecular biology [0.03%]
噬菌体群体中的磷-32:放射性同位素作为分子生物学历史痕迹的作用
Angela N H Creager
Angela N H Creager
The recent historiography of molecular biology features key technologies, instruments and materials, which offer a different view of the field and its turning points than preceding intellectual and institutional histories. Radioisotopes, in...
New wine in old bottles? The biotechnology problem in the history of molecular biology [0.03%]
新酒旧瓶?分子生物学史中的生物科技问题
Jean-Paul Gaudillière
Jean-Paul Gaudillière
This paper examines the "biotechnology problem" in the history of molecular biology, namely the alleged reinvention of a basic academic discipline looking for the logic of life, into a typical technoscientific enterprise, closely related to...
Soraya de Chadarevian
Soraya de Chadarevian
Microstudies and big picture accounts are often counterposed. This paper investigates the supposed dichotomy between the two historiographical approaches. In particular it investigates how the discussions are reflected in the historiography...